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Topological correctness plays a critical role in many image segmentation tasks, yet most networks are trained using pixel-wise loss functions, such as Dice, neglecting topological accuracy. Existing topology-aware methods often lack robust…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Laurin Lux , Alexander H. Berger , Alexander Weers , Nico Stucki , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

Existing research highlights the crucial role of topological priors in image segmentation, particularly in preserving essential structures such as connectivity and genus. Accurately capturing these topological features often requires…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Wenxiao Li , Xue-Cheng Tai , Jun Liu

Many recent medical segmentation systems rely on powerful deep learning models to solve highly specific tasks. To maximize performance, it is standard practice to evaluate numerous pipelines with varying model topologies, optimization…

Machine Learning · Computer Science 2019-11-06 Mathias Perslev , Erik Bjørnager Dam , Akshay Pai , Christian Igel

Modern deep neural networks have shown remarkable performance in medical image classification. However, such networks either emphasize pixel-intensity features instead of fundamental anatomical structures (e.g., those encoded by topological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Pengfei Gu , Huimin Li , Haoteng Tang , Dongkuan , Xu , Erik Enriquez , DongChul Kim , Bin Fu , Danny Z. Chen

Anatomical consistency in biomarker segmentation is crucial for many medical image analysis tasks. A promising paradigm for achieving anatomically consistent segmentation via deep networks is incorporating pixel connectivity, a basic…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Ziyun Yang , Sina Farsiu

Whole heart segmentation (WHS) supports cardiovascular disease (CVD) diagnosis, disease monitoring, treatment planning, and prognosis. Deep learning has become the most widely used method for WHS applications in recent years. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Chenyu Zhang , Wenxue Guan , Xiaodan Xing , Guang Yang

Although deep learning approaches have had tremendous success in image, video and audio processing, computer vision, and speech recognition, their applications to three-dimensional (3D) biomolecular structural data sets have been hindered…

Quantitative Methods · Quantitative Biology 2017-11-01 Zixuan Cang , Guo-Wei Wei

Image segmentation is to extract meaningful objects from a given image. For degraded images due to occlusions, obscurities or noises, the accuracy of the segmentation result can be severely affected. To alleviate this problem, prior…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Daoping Zhang , Lok Ming Lui

Accurate and reliable image segmentation is an essential part of biomedical image analysis. In this paper, we consider the problem of biomedical image segmentation using deep convolutional neural networks. We propose a new end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Amirhossein Dadashzadeh , Alireza Tavakoli Targhi

Motion artifacts caused by prolonged acquisition time are a significant challenge in Magnetic Resonance Imaging (MRI), hindering accurate tissue segmentation. These artifacts appear as blurred images that mimic tissue-like appearances,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Sunyoung Jung , Yoonseok Choi , Mohammed A. Al-masni , Minyoung Jung , Dong-Hyun Kim

Tensor networks provide an efficient approximation of operations involving high dimensional tensors and have been extensively used in modelling quantum many-body systems. More recently, supervised learning has been attempted with tensor…

Computer Vision and Pattern Recognition · Computer Science 2021-07-02 Raghavendra Selvan , Erik B Dam , Jens Petersen

Mammography images are widely used to detect non-palpable breast lesions or nodules, preventing cancer and providing the opportunity to plan interventions when necessary. The identification of some structures of interest is essential to…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Cesar A. Sierra-Franco , Jan Hurtado , Victor de A. Thomaz , Leonardo C. da Cruz , Santiago V. Silva , Alberto B. Raposo

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

Image segmentation is pivotal in medical image analysis, facilitating clinical diagnosis, treatment planning, and disease evaluation. Deep learning has significantly advanced automatic segmentation methodologies by providing superior…

Image and Video Processing · Electrical Eng. & Systems 2026-01-22 Zhengyong Huang , Ning Jiang , Xingwen Sun , Lihua Zhang , Peng Chen , Jens Domke , Yao Sui

Accurate segmentation of anatomical structures is vital for medical image analysis. The state-of-the-art accuracy is typically achieved by supervised learning methods, where gathering the requisite expert-labeled image annotations in a…

Computer Vision and Pattern Recognition · Computer Science 2020-12-04 Yuhang Lu , Kang Zheng , Weijian Li , Yirui Wang , Adam P. Harrison , Chihung Lin , Song Wang , Jing Xiao , Le Lu , Chang-Fu Kuo , Shun Miao

Topological accuracy in medical image segmentation is a highly important property for downstream applications such as network analysis and flow modeling in vessels or cell counting. Recently, significant methodological advancements have…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Alexander H. Berger , Nico Stucki , Laurin Lux , Vincent Buergin , Suprosanna Shit , Anna Banaszak , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

While conventional computer vision emphasizes pixel-level and feature-based objectives, medical image analysis of intricate biological structures necessitates explicit representation of their complex topological properties. Despite their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Yousef Yeganeh , Rui Xiao , Goktug Guvercin , Nassir Navab , Azade Farshad

The segmentation of medical images is a fundamental step in automated clinical decision support systems. Existing medical image segmentation methods based on supervised deep learning, however, remain problematic because of their reliance on…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Euijoon Ahn , Dagan Feng , Jinman Kim

Modern deep neural networks have achieved great successes in medical image analysis. However, the features captured by convolutional neural networks (CNNs) or Transformers tend to be optimized for pixel intensities and neglect key…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Yaopeng Peng , Hongxiao Wang , Milan Sonka , Danny Z. Chen

Automatic segmentation of neuronal topology is critical for handling large scale neuroimaging data, as it can greatly accelerate neuron annotation and analysis. However, the intricate morphology of neuronal branches and the occlusions among…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Huayu Fu , Jiamin Li , Haozhi Qu , Xiaolin Hu , Zengcai Guo