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We study a continuum model of an extensile active nematic to show that mesoscale turbulence develops in two stages: (i) ordered regions undergo an intrinsic hydrodynamic instability generating walls, lines of stong bend deformations, (ii)…

Soft Condensed Matter · Physics 2015-06-18 Sumesh P. Thampi , Ramin Golestanian , Julia M. Yeomans

Active nematic models explain the topological defects and flow patterns observed in epithelial tissues, but the nature of active stress-whether it is extensile or contractile, a key parameter of the theory-is not well established…

Soft Condensed Matter · Physics 2025-11-11 Jan Rozman , Sumesh P. Thampi , Julia M. Yeomans

Topological defects play a central role in the formation and organization of various biological systems. Historically, such nonequilibrium defects have been mainly studied in the context of homogeneous active nematics. Phase-separated…

Soft Condensed Matter · Physics 2023-07-13 Timo Krüger , Ivan Maryshev , Erwin Frey

Active fluids, such as cytoskeletal filaments, bacterial colonies and epithelial cell layers, exhibit distinctive orientational coherence, often characterized by nematic order and topological defects. By contrast, little is known about…

Soft Condensed Matter · Physics 2021-04-07 Mattia Serra , Linnea Lemma , Luca Giomi , Zvonimir Dogic , L. Mahadevan

Active processes drive and guide biological dynamics across scales -- from subcellular cytoskeletal remodelling, through tissue development in embryogenesis, to population-level bacterial colonies expansion. In each of these, biological…

Recent advances in cell biology and experimental techniques using reconstituted cell extracts have generated significant interest in understanding how geometry and topology influence active fluid dynamics. In this work, we present a…

Soft Condensed Matter · Physics 2024-05-13 Cuncheng Zhu , David Saintillan , Albert Chern

In this work, we report a direct measurement of the forces exerted by a tubulin/kinesin active nematic gel as well as its complete rheological characterization, including the quantification of its shear viscosity, {\eta}, and its activity…

Soft Condensed Matter · Physics 2024-04-22 Ignasi Vélez-Cerón , Pau Guillamat , Francesc Sagués , Jordi Ignés-Mullol

We present a data-driven framework for learning hydrodynamic equations from particle-based simulations of active matter. Our method leverages coarse-graining in both space and time to bridge microscopic particle dynamics with macroscopic…

Soft Condensed Matter · Physics 2026-02-18 Bappaditya Roy , Natsuhiko Yoshinaga

We introduce a data-driven approach to the modelling and analysis of viscous fluid mechanics. Instead of including constitutive laws for the fluid's viscosity in the mathematical model, we suggest to directly use experimental data. Only a…

Analysis of PDEs · Mathematics 2023-04-19 Christina Lienstromberg , Stefan Schiffer , Richard Schubert

Recent advances in high-resolution imaging techniques and particle-based simulation methods have enabled the precise microscopic characterization of collective dynamics in various biological and engineered active matter systems. In…

Soft Condensed Matter · Physics 2023-02-14 Rohit Supekar , Boya Song , Alasdair Hastewell , Gary P. T. Choi , Alexander Mietke , Jörn Dunkel

Dynamics of small particles, both living such as swimming bacteria and inanimate, such as colloidal spheres, has fascinated scientists for centuries. If one could learn how to control and streamline their chaotic motion, that would open…

Soft Condensed Matter · Physics 2023-02-08 Oleg D. Lavrentovich

The properties of liquid crystals can be modelled using an order parameter which describes the variability of the local orientation of rod-like molecules. Defects in the director field can arise due to external factors such as applied…

Numerical Analysis · Mathematics 2019-10-08 Craig S. MacDonald , John A. Mackenzie , Alison Ramage

We consider active nematodynamics on deformable surfaces. Based on a thermodynamically consistent surface Beris-Edwards model we add nematic activity and focus on the emerging additional coupling mechanism between the nematic field, the…

Soft Condensed Matter · Physics 2024-05-24 Ingo Nitschke , Axel Voigt

We study the spatiotemporal patterns that emerge when an active nematic film is topologically constraint. These topological constraints allow to control the non-equilibrium dynamics of the active system. We consider ellipsoidal shapes for…

Soft Condensed Matter · Physics 2017-03-13 Francesco Alaimo , Christian Köhler , Axel Voigt

We study emergent dynamics in a viscous drop subject to interfacial nematic activity. Using hydrodynamic simulations, we show how the interplay of nematodynamics, activity-driven flows and surface deformations gives rise to a sequence of…

Soft Condensed Matter · Physics 2024-04-19 Mohammadhossein Firouznia , David Saintillan

We consider the hydrodynamic theory of an active fluid of self-propelled particles with nematic aligning interactions. This class of materials has polar symmetry at the microscopic level, but forms macrostates of nematic symmetry. We…

Soft Condensed Matter · Physics 2012-04-17 Aparna Baskaran , M. Cristina Marchetti

A continuum model for a population of self-propelled particles interacting through nematic alignment is derived from an individual-based model. The methodology consists of introducing a hydrodynamic scaling of the corresponding mean-field…

Analysis of PDEs · Mathematics 2015-09-11 Pierre Degond , Angelika Manhart , Hui Yu

The macroscopic (population-level) dynamics of chemotactic cell movement -- arising from underlying microscopic (individual-based) models -- are often described by parabolic partial differential equations (PDEs) governing the…

Quantitative Methods · Quantitative Biology 2025-09-16 Radek Erban

The field of active nematics has traditionally employed descriptions based on dipolar activity, with interactions that align along a single axis. However, it has been theoretically predicted that interactions with a substrate, prevalent in…

We present a principled data-driven strategy for learning deterministic hydrodynamic models directly from stochastic non-equilibrium active particle trajectories. We apply our method to learning a hydrodynamic model for the propagating…

Soft Condensed Matter · Physics 2022-01-24 Suryanarayana Maddu , Quentin Vagne , Ivo F. Sbalzarini