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Ordinary differential equation models are nowadays widely used for the mechanistic description of biological processes and their temporal evolution. These models typically have many unknown and non-measurable parameters, which have to be…

Quantitative Methods · Quantitative Biology 2021-05-27 Alejandro F. Villaverde , Dilan Pathirana , Fabian Fröhlich , Jan Hasenauer , Julio R. Banga

Models for predicting the time of a future event are crucial for risk assessment, across a diverse range of applications. Existing time-to-event (survival) models have focused primarily on preserving pairwise ordering of estimated event…

Machine Learning · Statistics 2021-01-14 Paidamoyo Chapfuwa , Chenyang Tao , Lawrence Carin , Ricardo Henao

Fairness-aware statistical learning is essential for mitigating discrimination against protected attributes such as gender, race, and ethnicity in data-driven decision-making. This is particularly critical in high-stakes applications like…

Methodology · Statistics 2025-04-15 Fei Huang , Junhao Shen , Yanrong Yang , Ran Zhao

Explainable question answering systems predict an answer together with an explanation showing why the answer has been selected. The goal is to enable users to assess the correctness of the system and understand its reasoning process.…

Computation and Language · Computer Science 2020-10-14 Hendrik Schuff , Heike Adel , Ngoc Thang Vu

Obtaining reliable and accurate quantification of uncertainty estimates from deep neural networks is important in safety-critical applications. A well-calibrated model should be accurate when it is certain about its prediction and indicate…

Machine Learning · Computer Science 2020-12-16 Ranganath Krishnan , Omesh Tickoo

Accurate uncertainty estimates are important in sequential model-based decision-making tasks such as Bayesian optimization. However, these estimates can be imperfect if the data violates assumptions made by the model (e.g., Gaussianity).…

Machine Learning · Computer Science 2024-06-27 Shachi Deshpande , Charles Marx , Volodymyr Kuleshov

In classification problems, sampling bias between training data and testing data is critical to the ranking performance of classification scores. Such bias can be both unintentionally introduced by data collection and intentionally…

Methodology · Statistics 2017-11-02 Chandler Zuo

Mislabeled data is a pervasive issue that undermines the performance of machine learning systems in real-world applications. An effective approach to mitigate this problem is to detect mislabeled instances and subject them to special…

Machine Learning · Computer Science 2025-11-05 Ilies Chibane , Thomas George , Pierre Nodet , Vincent Lemaire

In human-in-the-loop machine learning, the user provides information beyond that in the training data. Many algorithms and user interfaces have been designed to optimize and facilitate this human--machine interaction; however, fewer studies…

Human-Computer Interaction · Computer Science 2018-03-12 Pedram Daee , Tomi Peltola , Aki Vehtari , Samuel Kaski

Artificial Intelligence (AI) models have demonstrated expert-level performance in melanoma detection, yet their clinical adoption is hindered by performance disparities across demographic subgroups such as gender, race, and age. Previous…

Machine Learning · Computer Science 2025-11-12 Brandon Dominique , Prudence Lam , Nicholas Kurtansky , Jochen Weber , Kivanc Kose , Veronica Rotemberg , Jennifer Dy

Functional near-infrared spectroscopy (fNIRS) is a valuable non-invasive tool for monitoring brain activity. The classification of fNIRS data in relation to conscious activity holds significance for advancing our understanding of the brain…

Machine Learning · Computer Science 2024-11-25 Zhihao Cao , Zizhou Luo

Model calibration is essential for ensuring that the predictions of deep neural networks accurately reflect true probabilities in real-world classification tasks. However, deep networks often produce over-confident or under-confident…

Machine Learning · Computer Science 2025-04-01 Jinxu Lin , Linwei Tao , Minjing Dong , Chang Xu

Machine learning is a powerful tool for predicting human-related outcomes, from credit scores to heart attack risks. But when deployed, learned models also affect how users act in order to improve outcomes, whether predicted or real. The…

Machine Learning · Computer Science 2020-06-24 Nir Rosenfeld , Sophie Hilgard , Sai Srivatsa Ravindranath , David C. Parkes

Assessing uncertainty is an important step towards ensuring the safety and reliability of machine learning systems. Existing uncertainty estimation techniques may fail when their modeling assumptions are not met, e.g. when the data…

Machine Learning · Computer Science 2017-01-24 Volodymyr Kuleshov , Stefano Ermon

Simulators are a critical component of modern robotics research. Strategies for both perception and decision making can be studied in simulation first before deployed to real world systems, saving on time and costs. Despite significant…

Machine Learning · Computer Science 2020-11-19 Bhairav Mehta , Ankur Handa , Dieter Fox , Fabio Ramos

The key concepts (calibration, discrimination, and discordance) important in understanding and comparing risk models are best conveyed graphically. To illustrate this, models predicting death and acute kidney injury in a large cohort of PCI…

Quantitative Methods · Quantitative Biology 2015-04-21 Ralph H. Stern , Dean E. Smith , Hitinder S. Gurm

Chemical multisensor devices need calibration algorithms to estimate gas concentrations. Their possible adoption as indicative air quality measurements devices poses new challenges due to the need to operate in continuous monitoring modes…

Artificial Intelligence · Computer Science 2020-02-14 S. De Vito , E. Esposito , M. Salvato , O. Popoola , F. Formisano , R. Jones , G. Di Francia

Calibration, the practice of choosing the parameters of a structural model to match certain empirical moments, can be viewed as minimum distance estimation. Existing standard error formulas for such estimators require a consistent estimate…

Econometrics · Economics 2024-06-19 Matthew D. Cocci , Mikkel Plagborg-Møller

Modern clinical practice relies on evidence-based guidelines implemented as compact scoring systems composed of a small number of interpretable decision rules. While machine-learning models achieve strong performance, many fail to translate…

Machine Learning · Computer Science 2026-05-25 Silas Ruhrberg Estévez , Christopher Chiu , Mihaela van der Schaar

Machine learning currently plays an increasingly important role in people's lives in areas such as credit scoring, auto-driving, disease diagnosing, and insurance quoting. However, in many of these areas, machine learning models have…

Machine Learning · Computer Science 2023-01-23 Zhuo Zhao
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