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Prediction uncertainty estimation has clinical significance as it can potentially quantify prediction reliability. Clinicians may trust 'blackbox' models more if robust reliability information is available, which may lead to more models…

Machine Learning · Computer Science 2022-10-04 Michael Dohopolski , Kai Wang , Biling Wang , Ti Bai , Dan Nguyen , David Sher , Steve Jiang , Jing Wang

Nodule malignancy assessment is a complex, time-consuming and error-prone task. Current clinical practice requires measuring changes in size and density of the nodule at different time-points. State of the art solutions rely on 3D…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel A. González Ballester

The CyberKnife system is a robotic radiosurgery platform that allows the delivery of lung SBRT treatments using fiducial-free soft-tissue tracking. However, not all lung cancer patients are eligible for lung tumor tracking. Tumor size,…

Medical Physics · Physics 2023-08-24 Matthieu Lafrenière , Gilmer Valdes , Martina Descovich

Deep learning has achieved impressive performance across various medical imaging tasks. However, its inherent bias against specific groups hinders its clinical applicability in equitable healthcare systems. A recently discovered phenomenon,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Kaouther Mouheb , Marawan Elbatel , Stefan Klein , Esther E. Bron

Machine learning classification tasks often benefit from predicting a set of possible labels with confidence scores to capture uncertainty. However, existing methods struggle with the high-dimensional nature of the data and the lack of…

Machine Learning · Computer Science 2024-07-08 Rui Luo , Zhixin Zhou

Objective: In clinical practice, small lung nodules can be easily overlooked by radiologists. The paper aims to provide an efficient and accurate detection system for small lung nodules while keeping good performance for large nodules.…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Sunyi Zheng , Ludo J. Cornelissen , Xiaonan Cui , Xueping Jing , Raymond N. J. Veldhuis , Matthijs Oudkerk , Peter M. A. van Ooijen

The construction of large datasets for deep learning has raised concerns regarding unauthorized use of online data, leading to increased interest in protecting data from third-parties who want to use it for training. The Convolution-based…

Machine Learning · Computer Science 2025-05-09 Dohyun Kim , Pedro Sandoval-Segura

Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang

Pulmonary lobe segmentation is an important task for pulmonary disease related Computer Aided Diagnosis systems (CADs). Classical methods for lobe segmentation rely on successful detection of fissures and other anatomical information such…

Computer Vision and Pattern Recognition · Computer Science 2019-04-11 Hao Tang , Chupeng Zhang , Xiaohui Xie

Radiologists possess diverse training and clinical experiences, leading to variations in the segmentation annotations of lung nodules and resulting in segmentation uncertainty.Conventional methods typically select a single annotation as the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Han Yang , Qiuli Wang , Yue Zhang , Zhulin An , Chen Liu , Xiaohong Zhang , S. Kevin Zhou

Deep learning (DL) has gained popularity in recent years as an effective tool for classifying the current health and predicting the future of industrial equipment. However, most DL models have black-box components with an underlying…

Machine Learning · Computer Science 2023-08-22 Hao Lu , Austin M. Bray , Chao Hu , Andrew T. Zimmerman , Hongyi Xu

Accurate lung lesion segmentation from Computed Tomography (CT) images is crucial to the analysis and diagnosis of lung diseases such as COVID-19 and lung cancer. However, the smallness and variety of lung nodules and the lack of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Changwei Wang , Rongtao Xu , Shibiao Xu , Weiliang Meng , Jun Xiao , Xiaopeng Zhang

Background and objective: Uncertainty quantification is a pivotal field that contributes to realizing reliable and robust systems. It becomes instrumental in fortifying safe decisions by providing complementary information, particularly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Jamil Fayyad , Shadi Alijani , Homayoun Najjaran

Pulmonary nodules may be an early manifestation of lung cancer, the leading cause of cancer-related deaths among both men and women. Numerous studies have established that deep learning methods can yield high-performance levels in the…

In recent years, the integration of deep learning techniques into medical imaging has revolutionized the diagnosis and treatment of lung diseases, particularly in the context of COVID-19 and pneumonia. This paper presents a novel,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-14 Md. Asiful Islam Miah , Shourin Paul , Sunanda Das , M. M. A. Hashem

Due to the complexity of annotation and inter-annotator variability, most lung nodule malignancy grading datasets contain label noise, which inevitably degrades the performance and generalizability of models. Although researchers adopt the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Xianze Ai , Zehui Liao , Yong Xia

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Wentao Zhu

Reliably detecting diseases using relevant biological information is crucial for real-world applicability of deep learning techniques in medical imaging. We debias deep learning models during training against unknown bias - without…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Simon Langer , Oliver Taubmann , Felix Denzinger , Andreas Maier , Alexander Mühlberg

Automated skin lesion classification using deep learning has shown remarkable accuracy, yet clinical adoption remains limited due to the "black box" nature of these models. We present MelanomaNet, an explainable deep learning system for…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Sukhrobbek Ilyosbekov

Aim: Early detection and correct diagnosis of lung cancer are the most important steps in improving patient outcome. This study aims to assess which deep learning models perform best in lung cancer diagnosis. Methods: Non-small cell lung…

Computer Vision and Pattern Recognition · Computer Science 2018-03-16 Zhang Li , Zheyu Hu , Jiaolong Xu , Tao Tan , Hui Chen , Zhi Duan , Ping Liu , Jun Tang , Guoping Cai , Quchang Ouyang , Yuling Tang , Geert Litjens , Qiang Li