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Lung cancer is the commonest cause of cancer deaths worldwide, and its mortality can be reduced significantly by performing early diagnosis and screening. Since the 1960s, driven by the pressing needs to accurately and effectively interpret…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Bo Liu , Wenhao Chi , Xinran Li , Peng Li , Wenhua Liang , Haiping Liu , Wei Wang , Jianxing He

Automatic pulmonary nodules classification is significant for early diagnosis of lung cancers. Recently, deep learning techniques have enabled remarkable progress in this field. However, these deep models are typically of high computational…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Hanliang Jiang , Fuhao Shen , Fei Gao , Weidong Han

We introduce CASED, a novel curriculum sampling algorithm that facilitates the optimization of deep learning segmentation or detection models on data sets with extreme class imbalance. We evaluate the CASED learning framework on the task of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Andrew Jesson , Nicolas Guizard , Sina Hamidi Ghalehjegh , Damien Goblot , Florian Soudan , Nicolas Chapados

Lung cancer remains one of the leading causes of morbidity and mortality worldwide, making early diagnosis critical for improving therapeutic outcomes and patient prognosis. Computer-aided diagnosis systems, which analyze computed…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Guohui Cai , Ying Cai , Zeyu Zhang , Yuanzhouhan Cao , Lin Wu , Daji Ergu , Zhinbin Liao , Yang Zhao

Deep learning-based methods have achieved promising performance in early detection and classification of lung nodules, most of which discard unsure nodules and simply deal with a binary classification -- malignant vs benign. Recently, an…

Computer Vision and Pattern Recognition · Computer Science 2021-01-28 Yiming Lei , Haiping Zhu , Junping Zhang , Hongming Shan

This paper introduces a novel deep-learning method for the automatic detection and segmentation of lung nodules, aimed at advancing the accuracy of early-stage lung cancer diagnosis. The proposed approach leverages a unique "Channel Squeeze…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mingxiu Sui , Jiacheng Hu , Tong Zhou , Zibo Liu , Likang Wen , Junliang Du

Early detection of lung nodules is of great importance in lung cancer screening. Existing research recognizes the critical role played by CAD systems in early detection and diagnosis of lung nodules. However, many CAD systems, which are…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Naji Khosravan , Ulas Bagci

Since radiologists have different training and clinical experiences, they may provide various segmentation annotations for a lung nodule. Conventional studies choose a single annotation as the learning target by default, but they waste…

Image and Video Processing · Electrical Eng. & Systems 2022-06-08 Han Yang , Lu Shen , Mengke Zhang , Qiuli Wang

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Lung nodule classification is a class imbalanced problem, as nodules are found with much lower frequency than non-nodules. In the class imbalanced problem, conventional classifiers tend to be overwhelmed by the majority class and ignore the…

Computer Vision and Pattern Recognition · Computer Science 2017-12-19 Masaharu Sakamoto , Hiroki Nakano , Kun Zhao , Taro Sekiyama

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Deep learning has shown tremendous progress in a wide range of digital pathology and medical image classification tasks. Its integration into safe clinical decision-making support requires robust and reliable models. However, real-world…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Abdur R. Fayjie , Jutika Borah , Florencia Carbone , Jan Tack , Patrick Vandewalle

Recently deep learning has been witnessing widespread adoption in various medical image applications. However, training complex deep neural nets requires large-scale datasets labeled with ground truth, which are often unavailable in many…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Wentao Zhu , Yeeleng S. Vang , Yufang Huang , Xiaohui Xie

To increase the transparency of modern computer-aided diagnosis (CAD) systems for assessing the malignancy of lung nodules, an interpretable model based on applying the generalized additive models and the concept-based learning is proposed.…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Rinat I. Dumaev , Sergei A. Molodyakov , Lev V. Utkin

Lung nodule detection is a class imbalanced problem because nodules are found with much lower frequency than non-nodules. In the class imbalanced problem, conventional classifiers tend to be overwhelmed by the majority class and ignore the…

Computer Vision and Pattern Recognition · Computer Science 2016-11-23 Masaharu Sakamoto , Hiroki Nakano

Learning exists in the context of data, yet notions of confidence typically focus on model predictions, not label quality. Confident learning (CL) is an alternative approach which focuses instead on label quality by characterizing and…

Machine Learning · Statistics 2022-08-23 Curtis G. Northcutt , Lu Jiang , Isaac L. Chuang

Discriminating lung nodules as malignant or benign is still an underlying challenge. To address this challenge, radiologists need computer aided diagnosis (CAD) systems which can assist in learning discriminative imaging features…

Computer Vision and Pattern Recognition · Computer Science 2018-10-15 Maria J. M. Chuquicusma , Sarfaraz Hussein , Jeremy Burt , Ulas Bagci

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

Lung cancer remains one of the most common and deadliest forms of cancer worldwide. The likelihood of successful treatment depends strongly on the stage at which the disease is diagnosed. Therefore, early detection of lung cancer represents…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Volodymyr Sydorskyi

In supervised machine learning, models are typically trained using data with hard labels, i.e., definite assignments of class membership. This traditional approach, however, does not take the inherent uncertainty in these labels into…

Machine Learning · Computer Science 2024-09-25 Sjoerd de Vries , Dirk Thierens