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Related papers: Brain Structural Saliency Over The Ages

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Recent efforts to improve the interpretability of deep neural networks use saliency to characterize the importance of input features to predictions made by models. Work on interpretability using saliency-based methods on Recurrent Neural…

Machine Learning · Computer Science 2019-10-29 Aya Abdelsalam Ismail , Mohamed Gunady , Luiz Pessoa , Héctor Corrada Bravo , Soheil Feizi

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

Machine Learning · Computer Science 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Recently, deep neural networks have demonstrated excellent performances in recognizing the age and gender on human face images. However, these models were applied in a black-box manner with no information provided about which facial…

Machine Learning · Statistics 2017-08-28 Sebastian Lapuschkin , Alexander Binder , Klaus-Robert Müller , Wojciech Samek

Deep learning builds the foundation for many medical image analysis tasks where neuralnetworks are often designed to have a large receptive field to incorporate long spatialdependencies. Recent work has shown that large receptive fields are…

Image and Video Processing · Electrical Eng. & Systems 2019-07-27 Nick Pawlowski , Ben Glocker

Grey matter loss in the hippocampus is a hallmark of neurobiological aging, yet understanding the corresponding changes in its functional connectivity remains limited. Seed-based functional connectivity (FC) analysis enables voxel-wise…

Neurons and Cognition · Quantitative Biology 2025-07-03 Yifei Sun , Marshall A. Dalton , Robert D. Sanders , Yixuan Yuan , Xiang Li , Sharon L. Naismith , Fernando Calamante , Jinglei Lv

Ageing impacts the brain's structural and functional organization and over time leads to various disorders, such as Alzheimer's disease and cognitive impairment. The process also impacts sensory function, bringing about a general slowing in…

Neurons and Cognition · Quantitative Biology 2022-09-07 L. J. Fosque , A. Alipour , M. Zare , R. V. Williams-Garcia , J. M. Beggs , G. Ortiz

The human electroencephalogram (EEG) of sleep undergoes profound changes with age. These changes can be conceptualized as "brain age", which can be compared to an age norm to reflect the deviation from normal aging process. Here, we develop…

Biomechanical modeling of tissue deformation can be used to simulate different scenarios of longitudinal brain evolution. In this work,we present a deep learning framework for hyper-elastic strain modelling of brain atrophy, during healthy…

Neurons and Cognition · Quantitative Biology 2021-08-19 Mariana Da Silva , Carole H. Sudre , Kara Garcia , Cher Bass , M. Jorge Cardoso , Emma C. Robinson

How can we improve the facial soft-biometric classification with help of the human visual system? This paper explores the use of saliency which is equivalent to the human visual system to classify Age, Gender and Facial Expression…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Ayesha Gurnani , Kenil Shah , Vandit Gajjar , Viraj Mavani , Yash Khandhediya

Longitudinal assessment of brain atrophy, particularly in the hippocampus, is a well-studied biomarker for neurodegenerative diseases, such as Alzheimer's disease (AD). In clinical trials, estimation of brain progressive rates can be…

Neurons and Cognition · Quantitative Biology 2023-04-11 Mengjin Dong , Long Xie , Sandhitsu R. Das , Jiancong Wang , Laura E. M. Wisse , Robin deFlores , David A. Wolk , Paul A. Yushkevich

Brain aging synthesis is a critical task with broad applications in clinical and computational neuroscience. The ability to predict the future structural evolution of a subject's brain from an earlier MRI scan provides valuable insights…

Machine Learning · Computer Science 2025-08-01 Ridvan Yesiloglu , Wei Peng , Md Tauhidul Islam , Ehsan Adeli

Knowledge of the human visual system helps to develop better computational models of visual attention. State-of-the-art models have been developed to mimic the visual attention system of young adults that, however, largely ignore the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Onkar Krishna , Kiyoharu Aizawa , Andrea Helo , Rama Pia

Understanding distinct neurological aging patterns across various populations is vital in the context of a globally aging populace. This study seeks to unravel the structural variations in the aging brain, taking into consideration…

Neurons and Cognition · Quantitative Biology 2024-08-15 Alphin J Thottupattu , Jayanthi Sivaswamy , Bharath Holla , Jithender Saini

Estimated brain age from magnetic resonance image (MRI) and its deviation from chronological age can provide early insights into potential neurodegenerative diseases, supporting early detection and implementation of prevention strategies.…

In this study, we propose the use of persistent homology -- specifically Betti curves for brain age prediction and for distinguishing between healthy and pathological aging. The proposed framework is applied to 100 structural MRI scans from…

Neurons and Cognition · Quantitative Biology 2025-11-11 Debanjali Bhattacharya , Neelam Sinha

Brain network provides important insights for the diagnosis of many brain disorders, and how to effectively model the brain structure has become one of the core issues in the domain of brain imaging analysis. Recently, various computational…

Neurons and Cognition · Quantitative Biology 2022-12-02 Zhengwang Xia , Tao Zhou , Saqib Mamoon , Amani Alfakih , Jianfeng Lu

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

Quantitative Methods · Quantitative Biology 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

Saliency methods are used extensively to highlight the importance of input features in model predictions. These methods are mostly used in vision and language tasks, and their applications to time series data is relatively unexplored. In…

Machine Learning · Computer Science 2020-10-28 Aya Abdelsalam Ismail , Mohamed Gunady , Héctor Corrada Bravo , Soheil Feizi

Understanding how large-scale functional brain networks reorganize during cognitive decline remains a central challenge in neuroimaging. While recent self-supervised models have shown promise for learning representations from resting-state…

Machine Learning · Computer Science 2026-03-03 Karanpartap Singh , Adam Turnbull , Mohammad Abbasi , Kilian Pohl , Feng Vankee Lin , Ehsan Adeli

Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…

Artificial Intelligence · Computer Science 2023-02-24 Mianxin Liu , Jingyang Zhang , Yao Wang , Yan Zhou , Fang Xie , Qihao Guo , Feng Shi , Han Zhang , Qian Wang , Dinggang Shen