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We propose a novel approach to identify one of the most significant dermoscopic criteria in the diagnosis of Cutaneous Melanoma: the Blue-whitish structure. In this paper, we achieve this goal in a Multiple Instance Learning framework using…

Computer Vision and Pattern Recognition · Computer Science 2015-07-01 Ali Madooei , Mark S. Drew , Hossein Hajimirsadeghi

Early detection of melanoma is crucial for improving survival rates. Current detection tools often utilize data-driven machine learning methods but often overlook the full integration of multiple datasets. We combine publicly available…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 SangHyuk Kim , Edward Gaibor , Brian Matejek , Daniel Haehn

Interpretation of medical images for diagnosis and treatment of complex disease from high-dimensional and heterogeneous data remains a key challenge in transforming healthcare. In the last few years, both supervised and unsupervised deep…

Image and Video Processing · Electrical Eng. & Systems 2018-12-20 Khalid Raza , Nripendra Kumar Singh

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Computer Vision and Pattern Recognition · Computer Science 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

An early detection of different tumor subtypes is crucial for an effective guidance to personalized therapy. While much efforts focus on decoding the sequence of DNA basis to detect the genetic mutations related to cancer, it is becoming…

In numerous studies, deep learning algorithms have proven their potential for the analysis of histopathology images, for example, for revealing the subtypes of tumors or the primary origin of metastases. These models require large datasets…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Jonathan Ganz , Jonas Ammeling , Samir Jabari , Katharina Breininger , Marc Aubreville

In this paper, we present a deep learning segmentation approach to classify and quantify the two most prevalent primary liver cancers - hepatocellular carcinoma and intrahepatic cholangiocarcinoma - from hematoxylin and eosin (H&E) stained…

Computer Vision and Pattern Recognition · Computer Science 2023-02-06 Miriam Hägele , Johannes Eschrich , Lukas Ruff , Maximilian Alber , Simon Schallenberg , Adrien Guillot , Christoph Roderburg , Frank Tacke , Frederick Klauschen

Prostate cancer is one of the main diseases affecting men worldwide. The gold standard for diagnosis and prognosis is the Gleason grading system. In this process, pathologists manually analyze prostate histology slides under microscope, in…

Image and Video Processing · Electrical Eng. & Systems 2021-05-24 Julio Silva-Rodríguez , Adrián Colomer , Jose Dolz , Valery Naranjo

The development of deep learning models in medical image analysis is majorly limited by the lack of large-sized and well-annotated datasets. Unsupervised learning does not require labels and is more suitable for solving medical image…

Computer Vision and Pattern Recognition · Computer Science 2023-01-06 Zi'an Xu , Yin Dai , Fayu Liu , Weibing Chen , Yue Liu , Lifu Shi , Sheng Liu , Yuhang Zhou

High-performance deep learning methods typically rely on large annotated training datasets, which are difficult to obtain in many clinical applications due to the high cost of medical image labeling. Existing data assessment methods…

Computer Vision and Pattern Recognition · Computer Science 2022-09-30 Chun-Yin Huang , Qi Lei , Xiaoxiao Li

Supervised deep learning algorithms have enabled significant performance gains in medical image classification tasks. But these methods rely on large labeled datasets that require resource-intensive expert annotation. Semi-supervised…

Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

Chromosome recognition is an essential task in karyotyping, which plays a vital role in birth defect diagnosis and biomedical research. However, existing classification methods face significant challenges due to the inter-class similarity…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ruijia Chang , Suncheng Xiang , Chengyu Zhou , Kui Su , Dahong Qian , Jun Wang

The examination of histopathology images is considered to be the gold standard for the diagnosis and stratification of cancer patients. A key challenge in the analysis of such images is their size, which can run into the gigapixels and can…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Joseph Boyd , Mykola Liashuha , Eric Deutsch , Nikos Paragios , Stergios Christodoulidis , Maria Vakalopoulou

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

While skin cancer detection has been a valuable deep learning application for years, its evaluation has often neglected the context in which testing images are assessed. Traditional melanoma classifiers assume that their testing…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Nick DiSanto , Gavin Harding , Ethan Martinez , Benjamin Sanders

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Melanoma is the deadliest form of skin cancer. While curable with early detection, only highly trained specialists are capable of accurately recognizing the disease. As expertise is in limited supply, automated systems capable of…

Computer Vision and Pattern Recognition · Computer Science 2016-10-19 Noel Codella , Quoc-Bao Nguyen , Sharath Pankanti , David Gutman , Brian Helba , Allan Halpern , John R. Smith

Histopathological image segmentation is a challenging and important topic in medical imaging with tremendous potential impact in clinical practice. State of the art methods rely on hand-crafted annotations which hinder clinical translation…

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