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To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-24 Xin Zhan , K. Grace Johnson , Aniello Esposito , Barbara Chapman , Marco Fiorentino , Kirk M. Bresniker , Raymond G. Beausoleil , Masoud Mohseni

Variational quantum algorithm (VQA), which is comprised of a classical optimizer and a parameterized quantum circuit, emerges as one of the most promising approaches for harvesting the power of quantum computers in the noisy intermediate…

Quantum Physics · Physics 2021-12-01 Samuel Stein , Yufei Ding , Nathan Wiebe , Bo Peng , Karol Kowalski , Nathan Baker , James Ang , Ang Li

Context: The emergence of quantum computing proposes a revolutionary paradigm that can radically transform numerous scientific and industrial application domains. The ability of quantum computers to scale computations beyond what the…

Quantum Physics · Physics 2024-08-07 Vlad Stirbu , Otso Kinanen , Majid Haghparast , Tommi Mikkonen

We present a composable design scheme for the development of hybrid quantum/classical algorithms and workflows for applications of quantum simulation. Our object-oriented approach is based on constructing an expressive set of common data…

The exploration of hybrid quantum-classical algorithms and programming models on noisy near-term quantum hardware has begun. As hybrid programs scale towards classical intractability, validation and benchmarking are critical to…

Quantum Physics · Physics 2019-03-06 Alexander McCaskey , Eugene Dumitrescu , Mengsu Chen , Dmitry Lyakh , Travis S. Humble

We present qcor - a language extension to C++ and compiler implementation that enables heterogeneous quantum-classical programming, compilation, and execution in a single-source context. Our work provides a first-of-its-kind C++ compiler…

Hybrid languages like the quantum intermediate representation (QIR) are essential for programming systems that mix quantum and conventional computing models, while execution of these programs is often deferred to a system-specific…

The prosperous development of both hardware and algorithms for quantum computing (QC) potentially prompts a paradigm shift in scientific computing in various fields. As an increasingly active topic in QC, the variational quantum algorithm…

Quantum Physics · Physics 2022-11-30 Yangyang Liu , Zhen Chen , Chang Shu , Siou Chye Chew , Boo Cheong Khoo , Xiang Zhao

Quantum error correction is vital for implementing universal quantum computing. A key component is the encoding circuit that maps a product state of physical qubits into the encoded multipartite entangled logical state. Known methods are…

Quantum Physics · Physics 2021-04-07 Xiaosi Xu , Simon C. Benjamin , Xiao Yuan

Quantum machine learning aims to release the prowess of quantum computing to improve machine learning methods. By combining quantum computing methods with classical neural network techniques we aim to foster an increase of performance in…

High Energy Physics - Phenomenology · Physics 2021-03-17 Andrew Blance , Michael Spannowsky

We define some of the programming and system-level challenges facing the application of quantum processing to high-performance computing. Alongside barriers to physical integration, prominent differences in the execution of quantum and…

Quantum Physics · Physics 2017-12-06 Keith A. Britt , Fahd A. Mohiyaddin , Travis S. Humble

Quantum circuit execution is the central task in quantum computation. Due to inherent quantum-mechanical constraints, quantum computing workflows often involve a considerable number of independent measurements over a large set of slightly…

Quantum Physics · Physics 2024-06-06 Daniel Claudino , Dmitry I. Lyakh , Alexander J. McCaskey

Quantum computers promise to transform our notions of computation by offering a completely new paradigm. To achieve scalable quantum computation, optimizing compilers and a corresponding software design flow will be essential. We present a…

Programming Languages · Computer Science 2018-07-24 Thomas Häner , Damian S. Steiger , Krysta Svore , Matthias Troyer

Achieving high-performance computation on quantum systems presents a formidable challenge that necessitates bridging the capabilities between quantum hardware and classical computing resources. This study introduces an innovative…

Quantum Physics · Physics 2024-03-19 Kuan-Cheng Chen , Xiaoren Li , Xiaotian Xu , Yun-Yuan Wang , Chen-Yu Liu

Recent computations involving quantum processing units (QPUs) have demonstrated a series of challenges inherent to hybrid classical-quantum programming, compilation, execution, and verification and validation. Despite considerable progress,…

Quantum Physics · Physics 2018-05-24 Alexander McCaskey , Eugene Dumitrescu , Dmitry Liakh , Travis Humble

Quantum computing has the potential to offer substantial computational advantages over conventional computing. Recent advances in quantum computing hardware and algorithms have enabled a class of classically parallel quantum workloads,…

Hybrid classical-quantum algorithms aim at variationally solving optimisation problems, using a feedback loop between a classical computer and a quantum co-processor, while benefitting from quantum resources. Here we present experiments…

Quantum machine learning is one of the fields where quantum computers are expected to bring advantages over classical methods. However, the limited size of current computers restricts the exploitation of the full potential of quantum…

Quantum Physics · Physics 2025-11-10 Juan C. Boschero , Ward van der Schoot , Niels M. P. Neumann

Deep learning is a modern approach to realize artificial intelligence. Many frameworks exist to implement the machine learning task; however, performance is limited by computing resources. Using a quantum computer to accelerate training is…

Quantum Physics · Physics 2019-01-29 Zhao-Yun Chen , Cheng Xue , Si-Ming Chen , Guo-Ping Guo

A variational framework for structural topology optimization is developed, integrating quantum and classical latent encoding strategies within a coordinate-based neural decoding architecture. In this approach, a low-dimensional latent…

Computational Engineering, Finance, and Science · Computer Science 2025-06-24 Alireza Tabarraei