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Patient data is widely used to estimate heterogeneous treatment effects and thus understand the effectiveness and safety of drugs. Yet, patient data includes highly sensitive information that must be kept private. In this work, we aim to…

Machine Learning · Computer Science 2025-03-06 Maresa Schröder , Valentyn Melnychuk , Stefan Feuerriegel

Causal inference plays a crucial role in scientific research across multiple disciplines. Estimating causal effects, particularly the average treatment effect (ATE), from observational data has garnered significant attention. However,…

Cryptography and Security · Computer Science 2025-12-17 Quan Yuan , Xiaochen Li , Linkang Du , Min Chen , Mingyang Sun , Yunjun Gao , Shibo He , Jiming Chen , Zhikun Zhang

Patient privacy is a major barrier to healthcare AI. For confidentiality reasons, most patient data remains in silo in separate hospitals, preventing the design of data-driven healthcare AI systems that need large volumes of patient data to…

Machine Learning · Computer Science 2023-10-11 Tatsuki Koga , Kamalika Chaudhuri , David Page

The estimation of conditional average treatment effects (CATEs) is an important topic in many scientific fields. CATEs can be estimated with high accuracy if data distributed across multiple parties are centralized. However, it is difficult…

Methodology · Statistics 2025-07-28 Yuji Kawamata , Ryoki Motai , Yukihiko Okada , Akira Imakura , Tetsuya Sakurai

The average treatment effect (ATE) is widely used to evaluate the effectiveness of drugs and other medical interventions. In safety-critical applications like medicine, reliable inferences about the ATE typically require valid uncertainty…

Machine Learning · Computer Science 2025-10-13 Maresa Schröder , Justin Hartenstein , Stefan Feuerriegel

This article proposes a meta-learning method for estimating the conditional average treatment effect (CATE) from a few observational data. The proposed method learns how to estimate CATEs from multiple tasks and uses the knowledge for…

Machine Learning · Statistics 2023-05-22 Tomoharu Iwata , Yoichi Chikahara

Differential privacy provides a formal framework for releasing statistical estimators that limit how much any single observation can influence the output, by injecting calibrated random noise. We study differentially private estimation in…

Statistics Theory · Mathematics 2026-05-26 Joowon Lee , Guanhua Chen

Estimating causal effects from observational data is essential in fields such as medicine, economics and social sciences, where privacy concerns are paramount. We propose a general, model-agnostic framework for differentially private…

Machine Learning · Computer Science 2026-02-02 Christian Janos Lebeda , Mathieu Even , Aurélien Bellet , Julie Josse

Robust estimation of heterogeneous treatment effects is a fundamental challenge for optimal decision-making in domains ranging from personalized medicine to educational policy. In recent years, predictive machine learning has emerged as a…

Machine Learning · Statistics 2025-06-23 Maximilian Schuessler , Erik Sverdrup , Robert Tibshirani

Many applications of machine learning, such as human health research, involve processing private or sensitive information. Privacy concerns may impose significant hurdles to collaboration in scenarios where there are multiple sites holding…

Machine Learning · Computer Science 2021-02-24 Hafiz Imtiaz , Jafar Mohammadi , Anand D. Sarwate

Conditional average treatment effects (CATEs) allow us to understand the effect heterogeneity across a large population of individuals. However, typical CATE learners assume all confounding variables are measured in order for the CATE to be…

Machine Learning · Computer Science 2022-02-01 Yao Zhang , Jeroen Berrevoets , Mihaela van der Schaar

When learning from sensitive data, care must be taken to ensure that training algorithms address privacy concerns. The canonical Private Aggregation of Teacher Ensembles, or PATE, computes output labels by aggregating the predictions of a…

Machine Learning · Computer Science 2022-09-23 Jiaqi Wang , Roei Schuster , Ilia Shumailov , David Lie , Nicolas Papernot

Differential Privacy (DP) is an important privacy-enhancing technology for private machine learning systems. It allows to measure and bound the risk associated with an individual participation in a computation. However, it was recently…

Machine Learning · Computer Science 2022-09-09 Cuong Tran , My H. Dinh , Ferdinando Fioretto

Imbalanced learning occurs in classification settings where the distribution of class-labels is highly skewed in the training data, such as when predicting rare diseases or in fraud detection. This class imbalance presents a significant…

Machine Learning · Computer Science 2024-11-11 Lucas Rosenblatt , Yuliia Lut , Eitan Turok , Marco Avella-Medina , Rachel Cummings

Experiment design has a rich history dating back over a century and has found many critical applications across various fields since then. The use and collection of users' data in experiments often involve sensitive personal information, so…

Cryptography and Security · Computer Science 2023-11-09 Wei-Ning Chen , Graham Cormode , Akash Bharadwaj , Peter Romov , Ayfer Özgür

Inferring the heterogeneous treatment effect is a fundamental problem in the sciences and commercial applications. In this paper, we focus on estimating Conditional Average Treatment Effect (CATE), that is, the difference in the conditional…

Methodology · Statistics 2021-03-23 Haomiao Meng , Xingye Qiao

Conditional Average Treatment Effects (CATE) estimation is one of the main challenges in causal inference with observational data. In addition to Machine Learning based-models, nonparametric estimators called meta-learners have been…

Machine Learning · Statistics 2023-06-06 Naoufal Acharki , Ramiro Lugo , Antoine Bertoncello , Josselin Garnier

There is growing interest in estimating and analyzing heterogeneous treatment effects in experimental and observational studies. We describe a number of meta-algorithms that can take advantage of any supervised learning or regression method…

Statistics Theory · Mathematics 2019-06-18 Sören R. Künzel , Jasjeet S. Sekhon , Peter J. Bickel , Bin Yu

In the social and health sciences, researchers often make causal inferences using sensitive variables. These researchers, as well as the data holders themselves, may be ethically and perhaps legally obligated to protect the confidentiality…

Methodology · Statistics 2024-08-28 Sharmistha Guha , Jerome P. Reiter

Applying machine learning (ML) to sensitive domains requires privacy protection of the underlying training data through formal privacy frameworks, such as differential privacy (DP). Yet, usually, the privacy of the training data comes at…

Machine Learning · Computer Science 2022-11-09 Franziska Boenisch , Christopher Mühl , Roy Rinberg , Jannis Ihrig , Adam Dziedzic
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