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Missing values are a notable challenge when analysing mass spectrometry-based proteomics data. While the field is still actively debating on the best practices, the challenge increased with the emergence of mass spectrometry-based…

Quantitative Methods · Quantitative Biology 2023-07-12 Christophe Vanderaa , Laurent Gatto

As more Intensive Care Unit (ICU) data becomes available, the interest in developing clinical prediction models to improve healthcare protocols increases. However, the lack of data quality still hinders clinical prediction using Machine…

Machine learning iterative imputation methods have been well accepted by researchers for imputing missing data, but they can be time-consuming when handling large datasets. To overcome this drawback, parallel computing strategies have been…

Applications · Statistics 2020-04-24 Shangzhi Hong , Yuqi Sun , Hanying Li , Henry S. Lynn

While reliable data-driven decision-making hinges on high-quality labeled data, the acquisition of quality labels often involves laborious human annotations or slow and expensive scientific measurements. Machine learning is becoming an…

Machine Learning · Statistics 2024-03-01 Tijana Zrnic , Emmanuel J. Candès

Standard approaches for variable selection in linear models are not tailored to deal properly with high-dimensional and incomplete data. Currently, methods dedicated to high-dimensional data handle missing values by ad-hoc strategies, like…

Methodology · Statistics 2021-06-09 Avner Bar-Hen , Vincent Audigier

Rule models are often preferred in prediction tasks with tabular inputs as they can be easily interpreted using natural language and provide predictive performance on par with more complex models. However, most rule models' predictions are…

Machine Learning · Computer Science 2023-11-27 Lena Stempfle , Fredrik D. Johansson

Pre-trained machine learning (ML) predictions have been increasingly used to complement incomplete data to enable downstream scientific inquiries, but their naive integration risks biased inferences. Recently, multiple methods have been…

Methodology · Statistics 2025-11-12 Xingran Chen , Tyler McCormick , Bhramar Mukherjee , Zhenke Wu

Missing data has a ubiquitous presence in real-life applications of machine learning techniques. Imputation methods are algorithms conceived for restoring missing values in the data, based on other entries in the database. The choice of the…

Machine Learning · Computer Science 2017-08-16 Unai Garciarena , Roberto Santana , Alexander Mendiburu

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

How to learn a good predictor on data with missing values? Most efforts focus on first imputing as well as possible and second learning on the completed data to predict the outcome. Yet, this widespread practice has no theoretical…

Machine Learning · Statistics 2021-12-01 Marine Le Morvan , Julie Josse , Erwan Scornet , Gaël Varoquaux

Multiple imputation is a highly recommended technique to deal with missing data, but the application to longitudinal datasets can be done in multiple ways. When a new wave of longitudinal data arrives, we can treat the combined data of…

Methodology · Statistics 2026-05-18 X. M. Kavelaars , S. van Buuren , J. R. van Ginkel

In recent times, a considerable number of research studies have been carried out to address the issue of Missing Value Imputation (MVI). MVI aims to provide a primary solution for datasets that have one or more missing attribute values. The…

Machine Learning · Computer Science 2024-10-14 Abu Fuad Ahmad , Khaznah Alshammari , Istiaque Ahmed , MD Shohel Sayed

Missing data are ubiquitous in empirical databases, yet statistical analyses typically require complete data matrices. Multiple imputation offers a principled solution for filling these gaps. This study evaluates the performance of several…

Computation · Statistics 2026-02-05 Enzo Porto Brasil

When fitting a generalized linear model -- such as a linear regression, a logistic regression, or a hierarchical linear model -- analysts often wonder how to handle missing values of the dependent variable Y. If missing values have been…

Methodology · Statistics 2017-03-27 Paul T. von Hippel

Return-to-baseline is an important method to impute missing values or unobserved potential outcomes when certain hypothetical strategies are used to handle intercurrent events in clinical trials. Current return-to-baseline approaches seen…

Methodology · Statistics 2021-11-19 Yongming Qu , Biyue Dai

Missing data is a common problem in practical data science settings. Various imputation methods have been developed to deal with missing data. However, even though the labels are available in the training data in many situations, the common…

Machine Learning · Computer Science 2025-01-30 Thu Nguyen , Tuan L. Vo , Pål Halvorsen , Michael A. Riegler

Missing value imputation is a fundamental challenge in machine intelligence, heavily dependent on data completeness. Current imputation methods often handle numerical and categorical attributes independently, overlooking critical…

Machine Learning · Computer Science 2026-01-09 Xiaopeng Luo , Zexi Tan , Zhuowei Wang

Prediction Rule Ensembles (PREs) are robust and interpretable statistical learning techniques with potential for predictive analytics, yet their efficacy in the presence of missing data is untested. This study uses multiple imputation to…

Applications · Statistics 2024-10-22 Vincent Schroeder , Jakob Schwerter , Marjolein Fokkema , Philipp Doebler

Large language model (LLM) evaluation is increasingly costly, prompting interest in methods that speed up evaluation by shrinking benchmark datasets. Benchmark prediction (also called efficient LLM evaluation) aims to select a small subset…

Machine Learning · Computer Science 2025-06-10 Guanhua Zhang , Florian E. Dorner , Moritz Hardt

The missing data issue is ubiquitous in health studies. Variable selection in the presence of both missing covariates and outcomes is an important statistical research topic but has been less studied. Existing literature focuses on…

Methodology · Statistics 2021-07-09 Liangyuan Hu , Jung-Yi Joyce Lin , Jiayi Ji
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