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Training large language models is generally done via optimization methods on clusters containing tens of thousands of accelerators, communicating over a high-bandwidth interconnect. Scaling up these clusters is expensive and can become…

Machine Learning · Computer Science 2025-06-13 Jari Kolehmainen , Nikolay Blagoev , John Donaghy , Oğuzhan Ersoy , Christopher Nies

We propose a novel approach for modeling chemical reactions within the particle-based Fokker-Planck framework for gas flow simulations which conserves mass, momentum, and energy while retaining the performance advantages of the…

Chemical Physics · Physics 2025-03-25 Leo Basov , Georgii Oblapenko , Martin Grabe

This paper presents an approch for modeling with one single kinetic mechanism the chemistry of the autoignition and combustion processes inside an internal combustion engine, as well as the chemical kinetics governing the post-oxidation of…

Chemical Physics · Physics 2009-03-24 Jörg Anderlohr , Roda Bounaceur , A. Pires Da Cruz , Frédérique Battin-Leclerc

We develop an online optimisation algorithm for in situ calibration of collision models in simulations of rarefied gas flows. The online optimised collision models are able to achieve similar accuracy to Direct Molecular Simulation (DMS) at…

Fluid Dynamics · Physics 2024-11-21 Nicholas Daultry Ball , Jonathan F. MacArt , Justin Sirignano

Deploying transformer-based neural networks on resource-constrained edge devices presents a significant challenge. This challenge is often addressed through various techniques, such as low-rank approximation and mixed-precision…

Machine Learning · Computer Science 2025-07-15 Ofir Gordon , Ariel Lapid , Elad Cohen , Yarden Yagil , Arnon Netzer , Hai Victor Habi

A computer-aided detection (CAD) system for the identification of lung internal nodules in low-dose multi-detector helical Computed Tomography (CT) images was developed in the framework of the MAGIC-5 project. The three modules of our lung…

Complex network data is prevalent in various real-world domains, including physical, technological, and biological systems. Despite this prevalence, predicting trends and understanding behavioral patterns in complex systems remain…

Symbolic Computation · Computer Science 2026-01-22 Zezheng Song , Chunmei Wang , Haizhao Yang

This paper presents an efficient approach for state estimation of post-combustion CO2 capture plants (PCCPs) by using reduced-order neural network models. The method involves extracting lower-dimensional feature vectors from…

Systems and Control · Electrical Eng. & Systems 2023-04-13 Siyu Liu , Xunyuan Yin , Jinfeng Liu

Deep learning models have become state of the art for natural language processing (NLP) tasks, however deploying these models in production system poses significant memory constraints. Existing compression methods are either lossy or…

Machine Learning · Computer Science 2018-11-05 Anish Acharya , Rahul Goel , Angeliki Metallinou , Inderjit Dhillon

The online optimization of gasoline blending benefits refinery economies. However, the nonlinear blending mechanism, the oil property fluctuations, and the blending model mismatch bring difficulties to the optimization. To solve the above…

Computational Engineering, Finance, and Science · Computer Science 2023-09-07 Muyi Huang , Renchu He , Xin Dai , Xin Peng , Wenli Du , Feng Qian

In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically…

Various kinetic Monte Carlo algorithms become inefficient when some of the population sizes in a system are large, which gives rise to a large number of reaction events per unit time. Here, we present a new acceleration algorithm based on…

Quantitative Methods · Quantitative Biology 2019-07-24 Yen Ting Lin , Song Feng , William S. Hlavacek

This paper introduces a new platform to accelerate the modeling of complex aerothermochemical interactions in new turbomachines, turbo-reactors, to decarbonise chemical processes. While previous work has aerothermally demonstrated the…

Computational Engineering, Finance, and Science · Computer Science 2025-02-13 Dylan Rubini , Budimir Rosic

Milestoning is an accurate and efficient method for rare event kinetics calculations by constructing a continuous-time kinetic network connecting the reactant and product states. However, even with adequate sampling, its accuracy can also…

Chemical Physics · Physics 2024-10-08 Xiaojun Ji , Hao Wang , Wenjian Liu

We introduce Conformal Online Learning of Koopman embeddings (COLoKe), a novel framework for adaptively updating Koopman-invariant representations of nonlinear dynamical systems from streaming data. Our modeling approach combines deep…

Machine Learning · Computer Science 2026-01-28 Ben Gao , Jordan Patracone , Stéphane Chrétien , Olivier Alata

Vector Quantization (VQ) is an appealing model compression method to obtain a tiny model with less accuracy loss. While methods to obtain better codebooks and codes under fixed clustering dimensionality have been extensively studied,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Zezhou Zhu , Yucong Zhou , Zhao Zhong

Molecular computation based on chemical reaction networks (CRNs) has emerged as a promising paradigm for designing programmable biochemical systems. However, the implementation of complex computations still requires excessively large and…

Molecular Networks · Quantitative Biology 2025-06-17 Renlei Jiang , Yuzhen Fan , Di Fan , Chuanhou Gao , Denis Dochain

A major theme in constraint-based modeling is unifying experimental data, such as biochemical information about the reactions that can occur in a system or the composition and localization of enzyme complexes, with highthroughput data…

Quantum chemical calculations on atomistic systems have evolved into a standard approach to study molecular matter. These calculations often involve a significant amount of manual input and expertise although most of this effort could be…

The complexity of binary droplet collisions increases for the collision of immiscible liquids with the occurrence of triple lines and thin encapsulating films. The Volume of Fluid (VOF) method is extended with an efficient interface…

Fluid Dynamics · Physics 2023-06-22 Johanna Potyka , Kathrin Schulte