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Deep learning models in medical imaging often fail when deployed in new clinical environments due to distribution shifts in demographics, scanner hardware, or acquisition protocols. A central challenge is underspecification, where models…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Moritz Stammel , Fabio De Sousa Ribeiro , Raghav Mehta , Mélanie Roschewitz , Ben Glocker

We propose a formal model for counterfactual estimation with unobserved confounding in "data-rich" settings, i.e., where there are a large number of units and a large number of measurements per unit. Our model provides a bridge between the…

Econometrics · Economics 2025-04-03 Alberto Abadie , Anish Agarwal , Devavrat Shah

Counterfactual inference is a useful tool for comparing outcomes of interventions on complex systems. It requires us to represent the system in form of a structural causal model, complete with a causal diagram, probabilistic assumptions on…

Estimating counterfactual outcomes over time from observational data is relevant for many applications (e.g., personalized medicine). Yet, state-of-the-art methods build upon simple long short-term memory (LSTM) networks, thus rendering…

Machine Learning · Computer Science 2022-06-06 Valentyn Melnychuk , Dennis Frauen , Stefan Feuerriegel

Prompt learning has garnered attention for its efficiency over traditional model training and fine-tuning. However, existing methods, constrained by inadequate theoretical foundations, encounter difficulties in achieving causally invariant…

Artificial Intelligence · Computer Science 2025-07-29 Xinshu Li , Ruoyu Wang , Erdun Gao , Mingming Gong , Lina Yao

Counterfactual examples for an input -- perturbations that change specific features but not others -- have been shown to be useful for evaluating bias of machine learning models, e.g., against specific demographic groups. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-07 Saloni Dash , Vineeth N Balasubramanian , Amit Sharma

Counterfactual image generation presents significant challenges, including preserving identity, maintaining perceptual quality, and ensuring faithfulness to an underlying causal model. While existing auto-encoding frameworks admit semantic…

Machine Learning · Computer Science 2025-06-10 Rajat Rasal , Avinash Kori , Fabio De Sousa Ribeiro , Tian Xia , Ben Glocker

Generating counterfactual explanations is one of the most effective approaches for uncovering the inner workings of black-box neural network models and building user trust. While remarkable strides have been made in generative modeling…

Machine Learning · Computer Science 2023-12-22 Nishtha Madaan , Srikanta Bedathur

This paper provides a comprehensive review of deep structural causal models (DSCMs), particularly focusing on their ability to answer counterfactual queries using observational data within known causal structures. It delves into the…

Machine Learning · Statistics 2025-02-04 Audrey Poinsot , Alessandro Leite , Nicolas Chesneau , Michèle Sébag , Marc Schoenauer

Estimating the effect of intervention from observational data while accounting for confounding variables is a key task in causal inference. Oftentimes, the confounders are unobserved, but we have access to large amounts of additional…

Machine Learning · Computer Science 2022-12-13 Shachi Deshpande , Kaiwen Wang , Dhruv Sreenivas , Zheng Li , Volodymyr Kuleshov

Recent advances in probabilistic generative modeling have motivated learning Structural Causal Models (SCM) from observational datasets using deep conditional generative models, also known as Deep Structural Causal Models (DSCM). If…

Machine Learning · Statistics 2023-01-24 Arash Nasr-Esfahany , Emre Kiciman

Model explanations based on pure observational data cannot compute the effects of features reliably, due to their inability to estimate how each factor alteration could affect the rest. We argue that explanations should be based on the…

Machine Learning · Statistics 2019-09-20 Álvaro Parafita , Jordi Vitrià

Counterfactual inference has become a ubiquitous tool in online advertisement, recommendation systems, medical diagnosis, and econometrics. Accurate modeling of outcome distributions associated with different interventions -- known as…

Machine Learning · Statistics 2021-07-13 Krikamol Muandet , Motonobu Kanagawa , Sorawit Saengkyongam , Sanparith Marukatat

Precision medicine involves answering counterfactual questions such as "Would this patient respond better to treatment A or treatment B?" These types of questions are causal in nature and require the tools of causal inference to be…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Jacob C. Reinhold , Aaron Carass , Jerry L. Prince

Referred to as the third rung of the causal inference ladder, counterfactual queries typically ask the "What if ?" question retrospectively. The standard approach to estimate counterfactuals resides in using a structural equation model that…

Machine Learning · Computer Science 2023-01-18 Edward De Brouwer

We assume to be given structural equations over discrete variables inducing a directed acyclic graph, namely, a structural causal model, together with data about its internal nodes. The question we want to answer is how we can compute…

Artificial Intelligence · Computer Science 2023-12-05 Marco Zaffalon , Alessandro Antonucci , Rafael Cabañas , David Huber , Dario Azzimonti

Counterfactual explanations have been successfully applied to create human interpretable explanations for various black-box models. They are handy for tasks in the image domain, where the quality of the explanations benefits from recent…

Machine Learning · Computer Science 2025-03-27 Trung Duc Ha , Sidney Bender

Predicting counterfactual distributions in complex dynamical systems is essential for scientific modeling and decision-making in domains such as public health and medicine. However, existing methods often rely on point estimates or purely…

Machine Learning · Computer Science 2025-09-15 Wenhao Mu , Zhi Cao , Mehmed Uludag , Alexander Rodríguez

Deep generative models can emulate the perceptual properties of complex image datasets, providing a latent representation of the data. However, manipulating such representation to perform meaningful and controllable transformations in the…

Machine Learning · Computer Science 2019-12-13 Michel Besserve , Arash Mehrjou , Rémy Sun , Bernhard Schölkopf

Causal learning has long concerned itself with the accurate recovery of underlying causal mechanisms. Such causal modelling enables better explanations of out-of-distribution data. Prior works on causal learning assume that the high-level…