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Solving for detailed chemical kinetics remains one of the major bottlenecks for computational fluid dynamics simulations of reacting flows using a finite-rate-chemistry approach. This has motivated the use of fully connected artificial…

Computational Engineering, Finance, and Science · Computer Science 2021-10-11 Opeoluwa Owoyele , Pinaki Pal

The search for pathways that optimize the formation of a particular target molecule in a reaction network is a key problem in many settings, including reactor systems. Chemical reaction networks are mathematically well represented as…

Molecular Networks · Quantitative Biology 2025-06-17 Adittya Pal , Rolf Fagerberg , Jakob Lykke Andersen , Christoph Flamm , Peter Dittrich , Daniel Merkle

Computational fluid dynamics (CFD)-driven machine learning frameworks based on symbolic regression offer a promising pathway for turbulence model discovery, but are often hindered by numerical instability, residual stagnation, and…

Fluid Dynamics · Physics 2026-05-13 Talib Ansari , Priyank H. Mehta , Harshal D. Akolekar

Automated knowledge discovery from trending chemical literature is essential for more efficient biomedical research. How to extract detailed knowledge about chemical reactions from the core chemistry literature is a new emerging challenge…

Computation and Language · Computer Science 2021-08-31 Chenkai Sun , Weijiang Li , Jinfeng Xiao , Nikolaus Nova Parulian , ChengXiang Zhai , Heng Ji

Concept Bottleneck Models (CBMs) improve the explainability of black-box Deep Learning (DL) by introducing intermediate semantic concepts. However, standard CBMs often overlook domain-specific relationships and causal mechanisms, and their…

Machine Learning · Computer Science 2026-01-16 Reza M. Asiyabi , SEOSAW Partnership , Steven Hancock , Casey Ryan

The combustion instability is investigated computationally for a multi-injector rocket engine using the flamelet progress variable (FPV) model. A C++ code is developed based on OpenFOAM 4.0 to apply the combustion model. Flamelet tables are…

Fluid Dynamics · Physics 2021-09-03 Lei Zhan , Tuan M. Nguyen , Juntao Xiong , Feng Liu , William A. Sirignano

Computational fluid dynamics (CFD) provides high-fidelity simulations of fluid flows but remains computationally expensive for many-query applications. In recent years deep learning (DL) has been used to construct data-driven fluid-dynamic…

Machine Learning · Computer Science 2026-04-13 David Ramos , Lucas Lacasa , Fermín Gutiérrez , Eusebio Valero , Gonzalo Rubio

An adpative integration technique for time advancement of particle motion in the context of coupled computational fluid dynamics (CFD) - discrete element method (DEM) simulations is presented in this work. CFD-DEM models provide an accurate…

Computational Physics · Physics 2018-02-28 Hariswaran Sitaraman , Ray Grout

Fusion-graded plasmas are one of the physically complex systems, resulting in continuous establishment of plasma theories for unclarified physical phenomena in order to thoroughly control nuclear fusion reactors. Deep learning has drawn…

Plasma Physics · Physics 2023-01-30 Semin Joung

The development of chemical engineering technology is a multi-stage process that encompasses laboratory research, scaling up, and industrial deployment. This process demands interdisciplinary col laboration and typically incurs significant…

Chemical Physics · Physics 2025-09-10 Heng Zhang , Jibin Zhou , Feiyang Xu , Jian Cui , Yi Li , Fan Yang , Hao Wang , Xin Li , Mao Ye

Atmospheric models demand a lot of computational power and solving the chemical processes is one of its most computationally intensive components. This work shows how to improve the computational performance of the Multiscale Online…

Recently, a novel two-phase framework named mol-infer for inference of chemical compounds with prescribed abstract structures and desired property values has been proposed. The framework mol-infer is primarily based on using mixed integer…

Machine Learning · Computer Science 2025-07-08 Jianshen Zhu , Naveed Ahmed Azam , Kazuya Haraguchi , Liang Zhao , Tatsuya Akutsu

Quantum mechanics/molecular mechanics (QM/MM) molecular dynamics (MD) simulations have been developed to simulate molecular systems, where an explicit description of changes in the electronic structure is necessary. However, QM/MM MD…

Chemical Physics · Physics 2021-04-15 Lennard Böselt , Moritz Thürlemann , Sereina Riniker

We present an Equation/Variable free machine learning (EVFML) framework for the control of the collective dynamics of complex/multiscale systems modelled via microscopic/agent-based simulators. The approach obviates the need for…

Dynamical Systems · Mathematics 2024-11-05 Dimitrios G. Patsatzis , Lucia Russo , Ioannis G. Kevrekidis , Constantinos Siettos

Computational techniques are required for narrowing down the vast space of possibilities to plausible prebiotic scenarios, since precise information on the molecular composition, the dominant reaction chemistry, and the conditions for that…

Molecular Networks · Quantitative Biology 2018-02-07 Jakob L. Andersen , Christoph Flamm , Daniel Merkle , Peter F. Stadler

We introduce generative models for accelerating simulations of complex systems through learning and evolving their effective dynamics. In the proposed Generative Learning of Effective Dynamics (G-LED), instances of high dimensional data are…

Machine Learning · Computer Science 2024-02-28 Han Gao , Sebastian Kaltenbach , Petros Koumoutsakos

A flexible treatment for gas- and aerosol-phase chemical processes has been developed for models of diverse scale, from box models up to global models. At the core of this novel framework is an "abstracted aerosol representation" that…

Computational Engineering, Finance, and Science · Computer Science 2021-11-16 Matthew L. Dawson , Christian Guzman , Jeffrey H. Curtis , Mario Acosta , Shupeng Zhu , Donald Dabdub , Andrew Conley , Matthew West , Nicole Riemer , Oriol Jorba

Deep learning is a hierarchical inference method formed by subsequent multiple layers of learning able to more efficiently describe complex relationships. In this work, Deep Gaussian Mixture Models are introduced and discussed. A Deep…

Machine Learning · Statistics 2017-11-21 Cinzia Viroli , Geoffrey J. McLachlan

The use of machine learning is becoming increasingly common in computational materials science. To build effective models of the chemistry of materials, useful machine-based representations of atoms and their compounds are required. We…

Materials Science · Physics 2021-08-02 Luis M. Antunes , Ricardo Grau-Crespo , Keith T. Butler

Thermal multi-phase flow simulations are indispensable to understanding the multi-scale and multi-physics phenomena in metal additive manufacturing (AM) processes, yet accurate and robust predictions remain challenging. This book chapter…

Computational Engineering, Finance, and Science · Computer Science 2022-06-13 Jinhui Yan , Qiming Zhu , Ze Zhao
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