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Understanding the chemical structure from a graphical representation of a molecule is a challenging image caption task that would greatly benefit molecule-centric scientific discovery. Variations in molecular images and caption subtasks…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Siqi Fan , Yuguang Xie , Bowen Cai , Ailin Xie , Gaochao Liu , Mu Qiao , Jie Xing , Zaiqing Nie

Predicting structural and energetic properties of a molecular system is one of the fundamental tasks in molecular simulations, and it has use cases in chemistry, biology, and medicine. In the past decade, the advent of machine learning…

Chemical Physics · Physics 2022-08-23 Sajjad Heydari , Stefano Raniolo , Lorenzo Livi , Vittorio Limongelli

The design and analysis of communication systems typically rely on the development of mathematical models that describe the underlying communication channel, which dictates the relationship between the transmitted and the received signals.…

Machine Learning · Computer Science 2017-08-01 Nariman Farsad , Andrea Goldsmith

Designing molecular structures with desired chemical properties is an essential task in drug discovery and material design. However, finding molecules with the optimized desired properties is still a challenging task due to combinatorial…

Biomolecules · Quantitative Biology 2023-02-02 Masatsugu Yamada , Mahito Sugiyama

Microtubule networks (MTs) are a component of a cell that may indicate the presence of various chemical compounds and can be used to recognize properties such as treatment resistance. Therefore, the classification of MT images is of great…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Aleksei Shpilman , Dmitry Boikiy , Marina Polyakova , Daniel Kudenko , Anton Burakov , Elena Nadezhdina

The maintenance, archiving and usage of the design drawings is cumbersome in physical form in different industries for longer period. It is hard to extract information by simple scanning of drawing sheets. Converting them to their digital…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Jesher Joshua M , Ragav V , Syed Ibrahim S P

Tackling molecular optimization problems using conventional computational methods is challenging, because the determination of the optimized configuration is known to be an NP-hard problem. Recently, there has been increasing interest in…

Applied Physics · Physics 2021-08-24 Eshan Joshi , Samuel Somuyiwa , Hossein Z. Jooya

Determining the aqueous solubility of molecules is a vital step in many pharmaceutical, environmental, and energy storage applications. Despite efforts made over decades, there are still challenges associated with developing a solubility…

Materials Science · Physics 2022-09-05 Gihan Panapitiya , Michael Girard , Aaron Hollas , Vijay Murugesan , Wei Wang , Emily Saldanha

Molecular representation learning methods typically tokenize molecules as individual atoms or use rigid, rule-based fragment decompositions, limiting their ability to capture meaningful chemical substructure context. We introduce…

Machine Learning · Computer Science 2026-05-26 Ankur Samanta , Rohan Gupta , Aditi Misra , Christian McIntosh Clarke , Jayakumar Rajadas

We report an interpretation method for deep learning models that allows us to handle high-dimensional spectral data in materials science. The proposed method uses feature extraction and clustering analysis to categorize materials into…

Materials Science · Physics 2025-10-21 Akira Takahashi , Yu Kumagai , Arata Takamatsu , Fumiyasu Oba

Switching between different levels of resolution is essential for multiscale modeling, but restoring details at higher resolution remains challenging. In our previous study we have introduced deepBackmap: a deep neural-network-based…

Chemical Physics · Physics 2024-06-12 Marc Stieffenhofer , Tristan Bereau , Michael Wand

According to density functional theory, any chemical property can be inferred from the electron density, making it the most informative attribute of an atomic structure. In this work, we demonstrate the use of established physical methods…

Materials Science · Physics 2023-09-12 Ethan M. Sunshine , Muhammed Shuaibi , Zachary W. Ulissi , John R. Kitchin

Recent advances in machine learning for molecules exhibit great potential for facilitating drug discovery from in silico predictions. Most models for molecule generation rely on the decomposition of molecules into frequently occurring…

Chemical Physics · Physics 2023-11-08 Leon Hetzel , Johanna Sommer , Bastian Rieck , Fabian Theis , Stephan Günnemann

Determining the structure and following the structural evolution of molecules undergoing chemical reactions is one of the key goals of ultrafast molecular physics and chemistry. Recently, Coulomb explosion imaging has emerged as a promising…

Graphs are ubiquitous data structures for representing interactions between entities. With an emphasis on the use of graphs to represent chemical molecules, we explore the task of learning to generate graphs that conform to a distribution…

Machine Learning · Computer Science 2019-03-08 Qi Liu , Miltiadis Allamanis , Marc Brockschmidt , Alexander L. Gaunt

Machine learning advances chemistry and materials science by enabling large-scale exploration of chemical space based on quantum chemical calculations. While these models supply fast and accurate predictions of atomistic chemical…

Chemical Physics · Physics 2019-06-25 K. T. Schütt , M. Gastegger , A. Tkatchenko , K. -R. Müller , R. J. Maurer

AI models for drug discovery and chemical literature mining must interpret molecular images and generate outputs consistent with 3D geometry and stereochemistry. Most molecular language models rely on strings or graphs, while…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Jing Lan , Hexiao Ding , Hongzhao Chen , Yufeng Jiang , Nga-Chun Ng , Gwing Kei Yip , Gerald W. Y. Cheng , Yunlin Mao , Jing Cai , Liang-ting Lin , Jung Sun Yoo

Patterns, which are collections of elements arranged in regular or near-regular arrangements, are an important graphic art form and widely used due to their elegant simplicity and aesthetic appeal. When a pattern is encoded as a flat image…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Pradyumna Reddy , Paul Guerrero , Matt Fisher , Wilmot Li , Miloy J. Mitra

Recent advances in self-supervised deep learning have improved our ability to quantify cellular morphological changes in high-throughput microscopy screens, a process known as morphological profiling. However, most current methods only…

Machine Learning · Computer Science 2026-05-18 Yemin Yu , Emre Hayir , Neil Tenenholtz , Lester Mackey , Ying Wei , David Alvarez-Melis , Ava P. Amini , Alex X. Lu

Deep learning is transforming many areas in science, and it has great potential in modeling molecular systems. However, unlike the mature deployment of deep learning in computer vision and natural language processing, its development in…

Computational Physics · Physics 2021-03-19 Jun Zhang , Yao-Kun Lei , Zhen Zhang , Junhan Chang , Maodong Li , Xu Han , Lijiang Yang , Yi Isaac Yang , Yi Qin Gao