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Non-negative Matrix Factorization (NMF) is an intensively used technique for obtaining parts-based, lower dimensional and non-negative representation. Researchers in biology, medicine, pharmacy and other fields often prefer NMF over other…

Machine Learning · Computer Science 2025-02-04 Matej Mihelčić , Pauli Miettinen

Dimensionality reduction is considered as an important step for ensuring competitive performance in unsupervised learning such as anomaly detection. Non-negative matrix factorization (NMF) is a popular and widely used method to accomplish…

Machine Learning · Computer Science 2021-02-08 Imtiaz Ahmed , Xia Ben Hu , Mithun P. Acharya , Yu Ding

Non-negative matrix factorization (NMF) is one of the most popular decomposition techniques for multivariate data. NMF is a core method for many machine-learning related computational problems, such as data compression, feature extraction,…

Numerical Analysis · Computer Science 2017-12-07 Gabriele Torre , Michael Graber

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

Genomics · Quantitative Biology 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

Non-negative matrix factorization (NMF) is a powerful tool for dimensionality reduction and clustering. Unfortunately, the interpretation of the clustering results from NMF is difficult, especially for the high-dimensional biological data…

Machine Learning · Computer Science 2021-04-28 Wenwen Min , Taosheng Xu , Xiang Wan , Tsung-Hui Chang

Non-negative matrix factorization (NMF) is a common method for generating topic models from text data. NMF is widely accepted for producing good results despite its relative simplicity of implementation and ease of computation. One…

Machine Learning · Computer Science 2016-08-09 Brendan Gavin , Vijay Gadepally , Jeremy Kepner

Nonnegative matrix factorization (NMF) has found many applications including topic modeling and document analysis. Hierarchical NMF (HNMF) variants are able to learn topics at various levels of granularity and illustrate their hierarchical…

Machine Learning · Computer Science 2022-02-16 Joshua Vendrow , Jamie Haddock , Deanna Needell

Nonnegative Matrix Factorization (NMF) is a widely applied technique in the fields of machine learning and data mining. Graph Regularized Non-negative Matrix Factorization (GNMF) is an extension of NMF that incorporates graph regularization…

Machine Learning · Computer Science 2024-03-19 Zhen Wang , Wenwen Min

An algorithm is described and tested that carries out a non negative matrix factorization (NMF) ignoring any stretching of the signal along the axis of the independent variable. This extended NMF model is called StretchedNMF. Variability in…

Symmetric nonnegative matrix factorization (SNMF) has demonstrated to be a powerful method for data clustering. However, SNMF is mathematically formulated as a non-convex optimization problem, making it sensitive to the initialization of…

Machine Learning · Computer Science 2021-03-03 Yuheng Jia , Hui Liu , Junhui Hou , Sam Kwong , Qingfu Zhang

Nonnegative matrix factorization (NMF) is a popular method used to reduce dimensionality in data sets whose elements are nonnegative. It does so by decomposing the data set of interest, $\mathbf{X}$, into two lower rank nonnegative matrices…

Methodology · Statistics 2021-07-05 Phillip Shreeves , Jeffrey L. Andrews , Xinchen Deng , Ramie Ali-Adeeb , Andrew Jirasek

Non-Negative Matrix Factorization (NMF) is a widely used dimension reduction method that factorizes a non-negative data matrix into two lower dimensional non-negative matrices: One is the basis or feature matrix which consists of the…

Applications · Statistics 2022-11-03 Yun Cai , Hong Gu , Toby Kenney

We introduce a probabilistic model with implicit norm regularization for learning nonnegative matrix factorization (NMF) that is commonly used for predicting missing values and finding hidden patterns in the data, in which the matrix…

Machine Learning · Computer Science 2022-08-23 Jun Lu , Christine P. Chai

Nonnegative matrix factorization (NMF) methods have proved to be powerful across a wide range of real-world clustering applications. Integrating multiple types of measurements for the same objects/subjects allows us to gain a deeper…

Machine Learning · Computer Science 2014-09-16 Daniel Hidru , Anna Goldenberg

Geometric graphs are a special kind of graph with geometric features, which are vital to model many scientific problems. Unlike generic graphs, geometric graphs often exhibit physical symmetries of translations, rotations, and reflections,…

Single-cell RNA sequencing (scRNA-seq) is a relatively new technology that has stimulated enormous interest in statistics, data science, and computational biology due to the high dimensionality, complexity, and large scale associated with…

Machine Learning · Statistics 2023-10-25 Yuta Hozumi , Guo-Wei Wei

Functionally Graded Materials (FGMs) made of soft constituents have emerged as promising material-structure systems in potential applications across many engineering disciplines, such as soft robots, actuators, energy harvesting, and tissue…

Computational Engineering, Finance, and Science · Computer Science 2025-07-01 Shiguang Deng , Horacio D. Espinosa , Wei Chen

Analyzing the structure of proteins is a key part of understanding their functions and thus their role in biology at the molecular level. In addition, design new proteins in a methodical way is a major engineering challenge. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-23 Hao Huang , Boulbaba Ben Amor , Xichan Lin , Fan Zhu , Yi Fang

We investigate a general matrix factorization for deviance-based data losses, extending the ubiquitous singular value decomposition beyond squared error loss. While similar approaches have been explored before, our method leverages…

Machine Learning · Statistics 2023-07-04 Liang Wang , Luis Carvalho

Brain tumor classification from magnetic resonance imaging, which is also known as MRI, plays a sensitive role in computer-assisted diagnosis systems. In recent years, deep learning models have achieved high classification accuracy.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Hiba Adil Al-kharsan , Róbert Rajkó