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Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

This study explores the potential of graph neural networks (GNNs) to enhance semantic segmentation across diverse image modalities. We evaluate the effectiveness of a novel GNN-based U-Net architecture on three distinct datasets: PascalVOC,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Aryan Singh , Pepijn Van de Ven , Ciarán Eising , Patrick Denny

Segmentation of brain structures on MRI is the primary step for further quantitative analysis of brain diseases. Manual segmentation is still considered the gold standard in terms of accuracy; however, such data is extremely time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Mengyu Li , Magnus Magnusson , Thilo van Eimeren , Lotta M. Ellingsen

Current advances in deep learning is leading to human-level accuracy in computer vision tasks such as object classification, localization, semantic segmentation, and instance segmentation. In this paper, we describe a new deep convolutional…

Computer Vision and Pattern Recognition · Computer Science 2020-10-07 N. Lakmal Deshapriya , Matthew N. Dailey , Manzul Kumar Hazarika , Hiroyuki Miyazaki

Probabilistic convolutional neural networks, which predict distributions of predictions instead of point estimates, led to recent advances in many areas of computer vision, from image reconstruction to semantic segmentation. Besides state…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Josef Lorenz Rumberger , Lisa Mais , Dagmar Kainmueller

This study addresses the essential task of medical image segmentation, which involves the automatic identification and delineation of anatomical structures and pathological regions in medical images. Accurate segmentation is crucial in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Seyedeh Sahar Taheri Otaghsara , Reza Rahmanzadeh

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta

Instance segmentation is critical in biomedical imaging to accurately distinguish individual objects like cells, which often overlap and vary in size. Recent query-based methods, where object queries guide segmentation, have shown strong…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Yaroslav Prytula , Illia Tsiporenko , Ali Zeynalli , Dmytro Fishman

Annotations are necessary to develop computer vision algorithms for histopathology, but dense annotations at a high resolution are often time-consuming to make. Deep learning models for segmentation are a way to alleviate the process, but…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Eduard Chelebian , Francesco Ciompi , Carolina Wählby

$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…

Brain imaging analysis is fundamental in neuroscience, providing valuable insights into brain structure and function. Traditional workflows follow a sequential pipeline-brain extraction, registration, segmentation, parcellation, network…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Yao Su , Keqi Han , Mingjie Zeng , Lichao Sun , Liang Zhan , Carl Yang , Lifang He , Xiangnan Kong

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as…

Segmentation and classification of large numbers of instances, such as cell nuclei, are crucial tasks in digital pathology for accurate diagnosis. However, the availability of high-quality datasets for deep learning methods is often limited…

Computer Vision and Pattern Recognition · Computer Science 2024-10-21 Laura Gálvez Jiménez , Christine Decaestecker

Over one in three people are affected by neurodegenerative disorders. Neural stem cells, which are multipotent regenerative cells with the potential to differentiate into any of the neural cell types, have immense therapeutic potential for…

Image and Video Processing · Electrical Eng. & Systems 2024-09-27 Nidhi Parthasarathy , Chandra Suda , Anika Mittal , Ian Young Chen , Ananya Jalihal

In this paper, we propose a new pre-training scheme for U-net based image segmentation. We first train the encoding arm as a localization network to predict the center of the target, before extending it into a U-net architecture for…

Neuron segmentation in electron microscopy (EM) aims to reconstruct the complete neuronal connectome; however, current deep learning-based methods are limited by their reliance on large-scale training data and extensive, time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Liuyun Jiang , Yanchao Zhang , Jinyue Guo , Yizhuo Lu , Ruining Zhou , Hua Han

This paper investigates the application of advanced image segmentation techniques to analyze C-fos immediate early gene expression, a crucial marker for neural activity. Due to the complexity and high variability of neural circuits,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Peilin Cai

The success of modern deep learning algorithms for image segmentation heavily depends on the availability of large datasets with clean pixel-level annotations (masks), where the objects of interest are accurately delineated. Lack of time…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Ekaterina Redekop , Alexey Chernyavskiy

Defect detection is a basic and essential task in automatic parts production, especially for automotive engine precision parts. In this paper, we propose a new idea to construct a deep convolutional network combining related knowledge of…

Computer Vision and Pattern Recognition · Computer Science 2018-10-30 Zhenshen Qu , Jianxiong Shen , Ruikun Li , Junyu Liu , Qiuyu Guan

Deep neural networks have achieved satisfactory performance in piles of medical image analysis tasks. However the training of deep neural network requires a large amount of samples with high-quality annotations. In medical image…

Computer Vision and Pattern Recognition · Computer Science 2020-07-08 Jixin Wang , Sanping Zhou , Chaowei Fang , Le Wang , Jinjun Wang