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Background and Aim: Recently, deep learning using convolutional neural network has been used successfully to classify the images of breast cells accurately. However, the accuracy of manual classification of those histopathological images is…

Image and Video Processing · Electrical Eng. & Systems 2021-08-11 Ashu Thapa , Abeer Alsadoon , P. W. C. Prasad , Simi Bajaj , Omar Hisham Alsadoon , Tarik A. Rashid , Rasha S. Ali , Oday D. Jerew

Accurate segmentation of lesions is crucial for diagnosis and treatment of early esophageal cancer (EEC). However, neither traditional nor deep learning-based methods up to today can meet the clinical requirements, with the mean Dice score…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Haipeng Li , Dingrui Liu , Yu Zeng , Shuaicheng Liu , Tao Gan , Nini Rao , Jinlin Yang , Bing Zeng

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Miriam Hägele , Philipp Seegerer , Sebastian Lapuschkin , Michael Bockmayr , Wojciech Samek , Frederick Klauschen , Klaus-Robert Müller , Alexander Binder

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

The classification of histopathological images is of great value in both cancer diagnosis and pathological studies. However, multiple reasons, such as variations caused by magnification factors and class imbalance, make it a challenging…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Yibao Sun , Xingru Huang , Yaqi Wang , Huiyu Zhou , Qianni Zhang

Deep intracranial tumors situated in eloquent brain regions controlling vital functions present critical diagnostic challenges. Clinical practice has shifted toward stereotactic biopsy for pathological confirmation before treatment. Yet…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Xinzhe Luo , Shuai Shao , Yan Wang , Jiangtao Wang , Yutong Bai , Jianguo Zhang

Breast cancer remains a leading cause of cancer-related mortality among women worldwide. Ultrasound imaging, widely used due to its safety and cost-effectiveness, plays a key role in early detection, especially in patients with dense breast…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Mohammad Abbadi , Yassine Himeur , Shadi Atalla , Wathiq Mansoor

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 MingXuan Xiao , Yufeng Li , Xu Yan , Min Gao , Weimin Wang

Breast cancer has reached the highest incidence rate worldwide among all malignancies since 2020. Breast imaging plays a significant role in early diagnosis and intervention to improve the outcome of breast cancer patients. In the past…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Luyang Luo , Xi Wang , Yi Lin , Xiaoqi Ma , Andong Tan , Ronald Chan , Varut Vardhanabhuti , Winnie CW Chu , Kwang-Ting Cheng , Hao Chen

Current pathology workflow involves staining of thin tissue slices, which otherwise would be transparent, followed by manual investigation under the microscope by a trained pathologist. While the hematoxylin and eosin (H&E) stain is…

Medical Physics · Physics 2021-05-04 Jingfang "Kelly" Zhang , Yuchen R. He , Nahil Sobh , Gabriel Popescu

Automatic detection of lymphocyte in H&E images is a necessary first step in lots of tissue image analysis algorithms. An accurate and robust automated lymphocyte detection approach is of great importance in both computer science and…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Jianxu Chen , Chukka Srinivas

Brain tumors are a complex and potentially life-threatening medical condition that requires accurate diagnosis and timely treatment. In this paper, we present a machine learning-based system designed to assist healthcare professionals in…

Image and Video Processing · Electrical Eng. & Systems 2023-04-18 Belal Badawy , Romario Sameh Samir , Youssef Tarek , Mohammed Ahmed , Rana Ibrahim , Manar Ahmed , Mohamed Hassan

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers and a leading cause of cancer deaths in the United States. Colorectal polyps that grow on the intima of the colon or rectum is an important precursor for CRC. Currently,…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Xinzi Sun , Pengfei Zhang , Dechun Wang , Yu Cao , Benyuan Liu

Bone marrow cytology is required to make a hematological diagnosis, influencing critical clinical decision points in hematology. However, bone marrow cytology is tedious, limited to experienced reference centers and associated with high…

Image and Video Processing · Electrical Eng. & Systems 2021-07-09 Rohollah Moosavi Tayebi , Youqing Mu , Taher Dehkharghanian , Catherine Ross , Monalisa Sur , Ronan Foley , Hamid R. Tizhoosh , Clinton JV Campbell

Endoscopy is the most widely used medical technique for cancer and polyp detection inside hollow organs. However, images acquired by an endoscope are frequently affected by illumination artefacts due to the enlightenment source orientation.…

Image and Video Processing · Electrical Eng. & Systems 2022-07-07 Axel Garcia-Vega , Ricardo Espinosa , Gilberto Ochoa-Ruiz , Thomas Bazin , Luis Eduardo Falcon-Morales , Dominique Lamarque , Christian Daul

Colonoscopy is the primary method for examination, detection, and removal of polyps. However, challenges such as variations among the endoscopists' skills, bowel quality preparation, and the complex nature of the large intestine contribute…

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff