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Related papers: ITTC @ TREC 2021 Clinical Trials Track

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This paper describes Toronto Metropolitan University's participation in the TREC Clinical Trials Track for 2023. As part of the tasks, we utilize advanced natural language processing techniques and neural language models in our experiments…

Computation and Language · Computer Science 2024-03-21 Aritra Kumar Lahiri , Emrul Hasan , Qinmin Vivian Hu , Cherie Ding

We describe team ielab from CSIRO and The University of Queensland's approach to the 2023 TREC Clinical Trials Track. Our approach was to use neural rankers but to utilise Large Language Models to overcome the issue of lack of training data…

Information Retrieval · Computer Science 2024-01-04 Shengyao Zhuang , Bevan Koopman , Guido Zuccon

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

Recruiting patients to participate in clinical trials can be challenging and time-consuming. Usually, participation in a clinical trial is initiated by a healthcare professional and proposed to the patient. Promoting clinical trials…

Computation and Language · Computer Science 2025-03-21 Mathilde Aguiar , Pierre Zweigenbaum , Nona Naderi

Clinical trials are a critical process in the medical field for introducing new treatments and innovations. However, cohort selection for clinical trials is a time-consuming process that often requires manual review of patient text records…

Computation and Language · Computer Science 2025-01-22 Chi-en Amy Tai , Xavier Tannier

Matching patients to clinical trials demands a systematic and reasoned interpretation of documents which require significant expert-level background knowledge, over a complex set of well-defined eligibility criteria. Moreover, this…

Computation and Language · Computer Science 2024-10-01 Mael Jullien , Alex Bogatu , Harriet Unsworth , Andre Freitas

This is the first year of the TREC Neural CLIR (NeuCLIR) track, which aims to study the impact of neural approaches to cross-language information retrieval. The main task in this year's track was ad hoc ranked retrieval of Chinese, Persian,…

Information Retrieval · Computer Science 2023-09-26 Dawn Lawrie , Sean MacAvaney , James Mayfield , Paul McNamee , Douglas W. Oard , Luca Soldaini , Eugene Yang

Objective: to provide a scoping review of papers on clinical natural language processing (NLP) tasks that use publicly available electronic health record data from a cohort of patients. Materials and Methods: We searched six databases,…

With the increasing number of clinical trial reports generated every day, it is becoming hard to keep up with novel discoveries that inform evidence-based healthcare recommendations. To help automate this process and assist medical experts,…

Computation and Language · Computer Science 2023-05-03 Juraj Vladika , Florian Matthes

Identifying cohorts of patients based on eligibility criteria such as medical conditions, procedures, and medication use is critical to recruitment for clinical trials. Such criteria are often most naturally described in free-text, using…

Computation and Language · Computer Science 2022-07-29 Nicholas J Dobbins , Tony Mullen , Ozlem Uzuner , Meliha Yetisgen

Natural language processing (NLP) of clinical trial documents can be useful in new trial design. Here we identify entity types relevant to clinical trial design and propose a framework called CT-BERT for information extraction from clinical…

Quantitative Methods · Quantitative Biology 2021-10-20 Xiong Liu , Greg L. Hersch , Iya Khalil , Murthy Devarakonda

Natural Language Processing (NLP) is a key technique for developing Medical Artificial Intelligence (AI) systems that leverage Electronic Health Record (EHR) data to build diagnostic and prognostic models. NLP enables the conversion of…

Recent advances in LLMs have greatly improved general-domain NLP tasks. Yet, their adoption in critical domains, such as clinical trial recruitment, remains limited. As trials are designed in natural language and patient data is represented…

Computation and Language · Computer Science 2026-01-01 Shrestha Ghosh , Moritz Schneider , Carina Reinicke , Carsten Eickhoff

ICLP is the premier international event for presenting research in logic programming. Contributions to ICLP 2021 were sought in all areas of logic programming, including but not limited to: Foundations: Semantics, Formalisms, Nonmonotonic…

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

Objective: Recent advances in language models have shown potential to adapt professional-facing biomedical literature to plain language, making it accessible to patients and caregivers. However, their unpredictability, combined with the…

Computation and Language · Computer Science 2025-07-23 Brian Ondov , William Xia , Kush Attal , Ishita Unde , Jerry He , Dina Demner-Fushman

Natural language processing (NLP) is an area of artificial intelligence that applies information technologies to process the human language, understand it to a certain degree, and use it in various applications. This area has rapidly…

The principal goal of the TREC Neural Cross-Language Information Retrieval (NeuCLIR) track is to study the impact of neural approaches to cross-language information retrieval. The track has created four collections, large collections of…

Information Retrieval · Computer Science 2024-04-15 Dawn Lawrie , Sean MacAvaney , James Mayfield , Paul McNamee , Douglas W. Oard , Luca Soldaini , Eugene Yang

Large Language Models (LLMs) are at the forefront of NLP achievements but fall short in dealing with shortcut learning, factual inconsistency, and vulnerability to adversarial inputs.These shortcomings are especially critical in medical…

Computation and Language · Computer Science 2024-04-09 Mael Jullien , Marco Valentino , André Freitas

How can we interpret and retrieve medical evidence to support clinical decisions? Clinical trial reports (CTR) amassed over the years contain indispensable information for the development of personalized medicine. However, it is practically…

Computation and Language · Computer Science 2023-10-31 Maël Jullien , Marco Valentino , Hannah Frost , Paul O'Regan , Donal Landers , André Freitas
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