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Graph Neural Network (GNN) architectures are defined by their implementations of update and aggregation modules. While many works focus on new ways to parametrise the update modules, the aggregation modules receive comparatively little…

Machine Learning · Computer Science 2023-10-11 Ryan Kortvelesy , Steven Morad , Amanda Prorok

Foundation models have shown remarkable cross-domain generalization in language and vision, inspiring the development of graph foundation models (GFMs). However, existing GFMs typically assume centralized access to multi-domain graphs,…

Machine Learning · Computer Science 2025-10-10 Zhengyu Wu , Yinlin Zhu , Xunkai Li , Ziang Qiu , Rong-Hua Li , Guoren Wang , Chenghu Zhou

Structure-informed protein representation learning is essential for effective protein function annotation and \textit{de novo} design. However, the presence of inherent noise in both crystal and AlphaFold-predicted structures poses…

Biomolecules · Quantitative Biology 2025-03-25 Zhongyue Zhang , Runze Ma , Yanjie Huang , Shuangjia Zheng

The recent integration of Graph Neural Networks (GNNs) into recommendation has led to a novel family of Collaborative Filtering (CF) approaches, namely Graph Collaborative Filtering (GCF). Following the same GNNs wave, recommender systems…

Gene expression programming, a genotype/phenotype genetic algorithm (linear and ramified), is presented here for the first time as a new technique for the creation of computer programs. Gene expression programming uses character linear…

Artificial Intelligence · Computer Science 2007-05-23 Candida Ferreira

Finding repeated patterns or motifs in a time series is an important unsupervised task that has still a number of open issues, starting by the definition of motif. In this paper, we revise the notion of motif support, characterizing it as…

Machine Learning · Computer Science 2016-12-06 Joan Serrà , Aleksandar Matic , Josep Luis Arcos , Alexandros Karatzoglou

We present a consistent system for referring crosscutting functionality, relating crosscutting concerns to specific implementation idioms, and formalizing their underlying relations through queries. The system is based on generic…

Software Engineering · Computer Science 2007-05-23 Marius Marin

An ensemble method that fuses the output decision vectors of multiple feedforward-designed convolutional neural networks (FF-CNNs) to solve the image classification problem is proposed in this work. To enhance the performance of the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-09 Yueru Chen , Yijing Yang , Wei Wang , C. -C. Jay Kuo

Learning-based optical flow estimation has been dominated with the pipeline of cost volume with convolutions for flow regression, which is inherently limited to local correlations and thus is hard to address the long-standing challenge of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Haofei Xu , Jing Zhang , Jianfei Cai , Hamid Rezatofighi , Dacheng Tao

Graph Neural Networks have become one of the indispensable tools to learn from graph-structured data, and their usefulness has been shown in wide variety of tasks. In recent years, there have been tremendous improvements in architecture…

Machine Learning · Statistics 2021-11-15 Sunil Kumar Maurya , Xin Liu , Tsuyoshi Murata

Providing architectural support is crucial for newly arising applications to achieve high performance and high system efficiency. Currently there is a trend in designing accelerators for special applications, while arguably a debate is…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-04 Yuhang Liu , Luming Wang , Xiang Li , Yang Wang , Mingyu Chen , Yungang Bao

One of the most challenging problems in recommender systems based on the collaborative filtering (CF) concept is data sparseness, i.e., limited user preference data is available for making recommendations. Cross-domain collaborative…

Information Retrieval · Computer Science 2013-12-25 Yue Shi , Martha Larson , Alan Hanjalic

AlphaFold 3 represents a transformative advancement in computational biology, enhancing protein structure prediction through novel multi-scale transformer architectures, biologically informed cross-attention mechanisms, and geometry-aware…

Biomolecules · Quantitative Biology 2025-08-27 Alireza Abbaszadeh , Armita Shahlaee

Glycans are structurally diverse and flexible biomolecules that play key roles in many biological processes. Their conformational variability makes the modeling of their interactions with proteins particularly challenging. This chapter…

Biomolecules · Quantitative Biology 2026-03-19 Victor Reys , Marco Giulini , Alexandre M. J. J. Bonvin

Summary: The vast generation of genetic data poses a significant challenge in efficiently uncovering valuable knowledge. Introducing GENEVIC, an AI-driven chat framework that tackles this challenge by bridging the gap between genetic data…

Quantitative Methods · Quantitative Biology 2024-04-09 Anindita Nath , Savannah Mwesigwa , Yulin Dai , Xiaoqian Jiang , Zhongming Zhao

The growing interests and applications of graph learning in diverse domains have propelled the development of a unified model generalizing well across different graphs and tasks, known as the Graph Foundation Model (GFM). Existing research…

Machine Learning · Computer Science 2025-06-17 Trung-Kien Nguyen , Heng Ping , Shixuan Li , Peiyu Zhang , Nikos Kanakaris , Nicholas Kotov , Paul Bogdan

The Unified Modeling Language (UML) community has started to define so-called profiles in order to better suit the needs of specific domains or settings. Product lines1 represent a special breed of systems they are extensible semi-finished…

Software Engineering · Computer Science 2014-10-16 Wolfgang Pree , Marcus Fontoura , Bernhard Rumpe

The last decade has seen the advent and consolidation of ontology based tools for the identification and biological interpretation of classes of genes, such as the Gene Ontology. The information accumulated time-by-time and included in the…

Molecular Networks · Quantitative Biology 2021-08-25 Salvatore Miccichè

Human genetics offers a promising route to therapeutic discovery, yet practical frameworks translating genotype-derived signal into ranked target and drug hypotheses remain limited, particularly when matched disease transcriptomics are…

Genomics · Quantitative Biology 2026-03-24 Muhammad Muneeb , David B. Ascher

Graph Neural Networks (GNNs) are neural models that leverage the dependency structure in graphical data via message passing among the graph nodes. GNNs have emerged as pivotal architectures in analyzing graph-structured data, and their…

Machine Learning · Computer Science 2024-03-19 Xu Zheng , Farhad Shirani , Tianchun Wang , Wei Cheng , Zhuomin Chen , Haifeng Chen , Hua Wei , Dongsheng Luo