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Federated learning offers a privacy-preserving framework for recommendation systems by enabling local data processing; however, data localization introduces substantial obstacles. Traditional federated recommendation approaches treat each…

Machine Learning · Computer Science 2026-03-10 Xudong Wang , Qingbo Hao , Yingyuan Xiao

Decreasing costs and new technologies have led to an increase in the amount of data available to plant breeding programs. High-throughput phenotyping (HTP) platforms routinely generate high-dimensional datasets of secondary features that…

Summary: Genotype networks are a method used in systems biology to study the innovability of a given phenotype, determining whether the phenotype is robust to mutations, and how do the genotypes associated to it are distributed in the…

Populations and Evolution · Quantitative Biology 2014-05-20 Giovanni Marco Dall'Olio , Ali R. Vahdati , Bertranpetit Jaume , Wagner Andreas , Laayouni Hafid

The goal of the present chapter is to explore the possibility of providing the research (but also the industrial) community that commonly uses spoken corpora with a stable portfolio of well-documented standardised formats that allow a high…

Computation and Language · Computer Science 2012-03-06 Laurent Romary , Andreas Witt

Background: The increasing volume and variety of genotypic and phenotypic data is a major defining characteristic of modern biomedical sciences. At the same time, the limitations in technology for generating data and the inherently…

Quantitative Methods · Quantitative Biology 2016-12-07 Yuxiang Jiang , Tal Ronnen Oron , Wyatt T Clark , Asma R Bankapur , Daniel D'Andrea , Rosalba Lepore , Christopher S Funk , Indika Kahanda , Karin M Verspoor , Asa Ben-Hur , Emily Koo , Duncan Penfold-Brown , Dennis Shasha , Noah Youngs , Richard Bonneau , Alexandra Lin , Sayed ME Sahraeian , Pier Luigi Martelli , Giuseppe Profiti , Rita Casadio , Renzhi Cao , Zhaolong Zhong , Jianlin Cheng , Adrian Altenhoff , Nives Skunca , Christophe Dessimoz , Tunca Dogan , Kai Hakala , Suwisa Kaewphan , Farrokh Mehryary , Tapio Salakoski , Filip Ginter , Hai Fang , Ben Smithers , Matt Oates , Julian Gough , Petri Törönen , Patrik Koskinen , Liisa Holm , Ching-Tai Chen , Wen-Lian Hsu , Kevin Bryson , Domenico Cozzetto , Federico Minneci , David T Jones , Samuel Chapman , Dukka B K. C. , Ishita K Khan , Daisuke Kihara , Dan Ofer , Nadav Rappoport , Amos Stern , Elena Cibrian-Uhalte , Paul Denny , Rebecca E Foulger , Reija Hieta , Duncan Legge , Ruth C Lovering , Michele Magrane , Anna N Melidoni , Prudence Mutowo-Meullenet , Klemens Pichler , Aleksandra Shypitsyna , Biao Li , Pooya Zakeri , Sarah ElShal , Léon-Charles Tranchevent , Sayoni Das , Natalie L Dawson , David Lee , Jonathan G Lees , Ian Sillitoe , Prajwal Bhat , Tamás Nepusz , Alfonso E Romero , Rajkumar Sasidharan , Haixuan Yang , Alberto Paccanaro , Jesse Gillis , Adriana E Sedeño-Cortés , Paul Pavlidis , Shou Feng , Juan M Cejuela , Tatyana Goldberg , Tobias Hamp , Lothar Richter , Asaf Salamov , Toni Gabaldon , Marina Marcet-Houben , Fran Supek , Qingtian Gong , Wei Ning , Yuanpeng Zhou , Weidong Tian , Marco Falda , Paolo Fontana , Enrico Lavezzo , Stefano Toppo , Carlo Ferrari , Manuel Giollo , Damiano Piovesan , Silvio Tosatto , Angela del Pozo , José M Fernández , Paolo Maietta , Alfonso Valencia , Michael L Tress , Alfredo Benso , Stefano Di Carlo , Gianfranco Politano , Alessandro Savino , Hafeez Ur Rehman , Matteo Re , Marco Mesiti , Giorgio Valentini , Joachim W Bargsten , Aalt DJ van Dijk , Branislava Gemovic , Sanja Glisic , Vladmir Perovic , Veljko Veljkovic , Nevena Veljkovic , Danillo C Almeida-e-Silva , Ricardo ZN Vencio , Malvika Sharan , Jörg Vogel , Lakesh Kansakar , Shanshan Zhang , Slobodan Vucetic , Zheng Wang , Michael JE Sternberg , Mark N Wass , Rachael P Huntley , Maria J Martin , Claire O'Donovan , Peter N Robinson , Yves Moreau , Anna Tramontano , Patricia C Babbitt , Steven E Brenner , Michal Linial , Christine A Orengo , Burkhard Rost , Casey S Greene , Sean D Mooney , Iddo Friedberg , Predrag Radivojac

Artificial Intelligence methods are powerful tools for biological image analysis and processing. High-quality annotated images are key to training and developing new methods, but access to such data is often hindered by the lack of…

Protein structure prediction models such as AlphaFold3 (AF3) push the frontier of biomolecular modeling by incorporating science-informed architectural changes to the transformer architecture. However, these advances come at a steep system…

Biomolecules · Quantitative Biology 2025-06-27 Hoa La , Ahan Gupta , Alex Morehead , Jianlin Cheng , Minjia Zhang

Graph neural networks (GNNs) have become compelling models designed to perform learning and inference on graph-structured data. However, little work has been done to understand the fundamental limitations of GNNs for scaling to larger…

Machine Learning · Computer Science 2023-10-27 Hyungeun Lee , Kijung Yoon

Graph Neural Networks (GNNs) have substantially advanced the field of recommender systems. However, despite the creation of more than a thousand knowledge graphs (KGs) under the W3C standard RDF, their rich semantic information has not yet…

Information Retrieval · Computer Science 2025-06-11 Michael Färber , David Lamprecht , Yuni Susanti

A biological experiment is the most reliable way of assigning function to a protein. However, in the era of high-throughput sequencing, scientists are unable to carry out experiments to determine the function of every single gene product.…

Quantitative Methods · Quantitative Biology 2016-01-07 Iddo Friedberg , Predrag Radivojac

Nowadays, due to the increasing amount of experimental data obtained by sequencing, the most interest is focused on determining the functions and characteristics of its individual parts of the genome instead of determining the nucleotide…

Genomics · Quantitative Biology 2021-02-09 Marina Galchenkova , Aleksei Korzhenkov

Collecting and annotating morphological data present significant challenges, requiring linguistic expertise, methodological rigour, and substantial resources. These barriers are particularly acute for low-resource languages and varieties.…

Computation and Language · Computer Science 2026-04-07 Aso Mahmudi , Sina Ahmadi , Kemal Kurniawan , Rico Sennrich , Eduard Hovy , Ekaterina Vylomova

Foundation models for single-cell RNA sequencing (scRNA-seq) have shown promising capabilities in capturing gene expression patterns. However, current approaches face critical limitations: they ignore biological prior knowledge encoded in…

Machine Learning · Computer Science 2025-03-04 Mufan Qiu , Xinyu Hu , Fengwei Zhan , Sukwon Yun , Jie Peng , Ruichen Zhang , Bhavya Kailkhura , Jiekun Yang , Tianlong Chen

The effective visualization of genomic data is crucial for exploring and interpreting complex relationships within and across genes and genomes. Despite advances in developing dedicated bioinformatics software, common visualization tools…

Genomics · Quantitative Biology 2024-11-22 Thomas Hackl , Markus Ankenbrand , Bart van Adrichem , David Wilkins , Kristina Haslinger

In this paper we attempt to address the problem of geometric multi-model fitting with resorting to a few weakly annotated (WA) data points, which has been sparsely studied so far. In weak annotating, most of the manual annotations are…

Computer Vision and Pattern Recognition · Computer Science 2020-01-22 Chao Zhang , Xuequan Lu , Katsuya Hotta , Xi Yang

The Gene Ontology (GO) project is the largest resource for cataloguing gene function. The combination of solid conceptual underpinnings and a practical set of features have made the GO a widely adopted resource in the research community and…

Genomics · Quantitative Biology 2016-12-07 Pascale Gaudet , Nives Škunca , James C. Hu , Christophe Dessimoz

Graph Foundation Models (GFMs) are emerging as a significant research topic in the graph domain, aiming to develop graph models trained on extensive and diverse data to enhance their applicability across various tasks and domains.…

Machine Learning · Computer Science 2024-06-03 Haitao Mao , Zhikai Chen , Wenzhuo Tang , Jianan Zhao , Yao Ma , Tong Zhao , Neil Shah , Mikhail Galkin , Jiliang Tang

This letter introduces EGGCodec, a robust neural Encodec framework engineered for electroglottography (EGG) signal reconstruction and F0 extraction. We propose a multi-scale frequency-domain loss function to capture the nuanced relationship…

Audio and Speech Processing · Electrical Eng. & Systems 2025-08-13 Rui Feng , Yuang Chen , Yu Hu , Jun Du , Jiahong Yuan

Recently, graph neural networks (GNNs) have been successfully applied to recommender systems. In recommender systems, the user's feedback behavior on an item is usually the result of multiple factors acting at the same time. However, a…

Information Retrieval · Computer Science 2020-07-14 Dongbo Xi , Fuzhen Zhuang , Yongchun Zhu , Pengpeng Zhao , Xiangliang Zhang , Qing He

Gene studies are crucial for fields such as protein structure prediction, drug discovery, and cancer genomics, yet they face challenges in fully utilizing the vast and diverse information available. Gene studies require clean, factual…

Databases · Computer Science 2024-12-18 Yuwei Miao , Yuzhi Guo , Hehuan Ma , Jingquan Yan , Feng Jiang , Weizhi An , Jean Gao , Junzhou Huang