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The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

Machine Learning · Computer Science 2017-12-06 Jakub M. Tomczak , Maximilian Ilse , Max Welling

Labeling medical images depends on professional knowledge, making it difficult to acquire large amount of annotated medical images with high quality in a short time. Thus, making good use of limited labeled samples in a small dataset to…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Peng Jiang , Juan Liu , Lang Wang , Zhihui Ynag , Hongyu Dong , Jing Feng

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Zizhao Zhang , Yuanpu Xie , Fuyong Xing , Mason McGough , Lin Yang

Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell…

Quantitative Methods · Quantitative Biology 2023-11-02 Jakub R. Kaczmarzyk , Tahsin M. Kurc , Shahira Abousamra , Rajarsi Gupta , Joel H. Saltz , Peter K. Koo

Although CNNs are widely considered as the state-of-the-art models in various applications of image analysis, one of the main challenges still open is the training of a CNN on high resolution images. Different strategies have been proposed…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Nadia Brancati , Giuseppe De Pietro , Daniel Riccio , Maria Frucci

Precise medical image segmentation is fundamental for enabling computer aided diagnosis and effective treatment planning. Traditional models that rely solely on visual features often struggle when confronted with ambiguous or low contrast…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Ashfak Yeafi , Parthaw Goswami , Md Khairul Islam , Ashifa Islam Shamme

In recent years, significant progress has been made in the medical image analysis domain using convolutional neural networks (CNNs). In particular, deep neural networks based on a U-shaped architecture (UNet) with skip connections have been…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Vamsi Krishna Vasa , Wenhui Zhu , Xiwen Chen , Peijie Qiu , Xuanzhao Dong , Yalin Wang

Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Zhiling Yan , Sicheng Chen , Tianyi Zhang , Nan Ying , Yanli Lei , Guanglei Zhang

Recently, automated medical image segmentation methods based on deep learning have achieved great success. However, they heavily rely on large annotated datasets, which are costly and time-consuming to acquire. Few-shot learning aims to…

Artificial Intelligence · Computer Science 2024-08-20 Jiayu Huo , Ruiqiang Xiao , Haotian Zheng , Yang Liu , Sebastien Ourselin , Rachel Sparks

Automatic integration of whole slide images (WSIs) and gene expression profiles has demonstrated substantial potential in precision clinical diagnosis and cancer progression studies. However, most existing studies focus on individual gene…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Junzhuo Liu , Xuemei Du , Daniel Reisenbuchler , Ye Chen , Markus Eckstein , Christian Matek , Friedrich Feuerhake , Dorit Merhof

Convolutional neural networks for visual recognition require large amounts of training samples and usually benefit from data augmentation. This paper proposes PatchMix, a data augmentation method that creates new samples by composing…

Computer Vision and Pattern Recognition · Computer Science 2022-04-04 Paola Cascante-Bonilla , Arshdeep Sekhon , Yanjun Qi , Vicente Ordonez

Transformer-based architectures start to emerge in single image super resolution (SISR) and have achieved promising performance. Most existing Vision Transformers divide images into the same number of patches with a fixed size, which may…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Qing Cai , Yiming Qian , Jinxing Li , Jun Lv , Yee-Hong Yang , Feng Wu , David Zhang

Attention-based models are proliferating in the space of image analytics, including segmentation. The standard method of feeding images to transformer encoders is to divide the images into patches and then feed the patches to the model as a…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Enzhi Zhang , Isaac Lyngaas , Peng Chen , Xiao Wang , Jun Igarashi , Yuankai Huo , Mohamed Wahib , Masaharu Munetomo

Training end-to-end networks for classifying gigapixel size histopathological images is computationally intractable. Most approaches are patch-based and first learn local representations (patch-wise) before combining these local…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Sachin Mehta , Ximing Lu , Donald Weaver , Joann G. Elmore , Hannaneh Hajishirzi , Linda Shapiro

We propose a novel unsupervised cross-modal homography estimation learning framework, named Split Supervised Homography estimation Network (SSHNet). SSHNet reformulates the unsupervised cross-modal homography estimation into two supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Junchen Yu , Si-Yuan Cao , Runmin Zhang , Chenghao Zhang , Zhu Yu , Shujie Chen , Bailin Yang , Hui-liang Shen

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

Image and Video Processing · Electrical Eng. & Systems 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

In biomedical imaging, deep learning-based methods are state-of-the-art for every modality (virtual slides, MRI, etc.) In histopathology, these methods can be used to detect certain biomarkers or classify lesions. However, such techniques…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Adrien Nivaggioli , Nicolas Pozin , Rémy Peyret , Stéphane Sockeel , Marie Sockeel , Nicolas Nerrienet , Marceau Clavel , Clara Simmat , Catherine Miquel

Image classifiers are information-discarding machines, by design. Yet, how these models discard information remains mysterious. We hypothesize that one way for image classifiers to reach high accuracy is to first zoom to the most…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Mohammad Reza Taesiri , Giang Nguyen , Sarra Habchi , Cor-Paul Bezemer , Anh Nguyen

Cancer is an abnormal growth with potential to invade locally and metastasize to distant organs. Accurate auto-segmentation of the tumor and surrounding normal tissues is required for radiotherapy treatment plan optimization. Recent…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Syed Haider Ali , Asrar Ahmad , Muhammad Ali , Asifullah Khan , Nadeem Shaukat

Accurate classification of breast ultrasound images into benign, malignant, and normal categories is a critical clinical task complicated by speckle noise, acoustic shadowing, and inter-class visual ambiguity. Existing deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Chinedu Emmanuel Mbonu , Blessing Nwamaka Iduh , Joseph Ikechukwu Odo , Doris Chinedu Asogwa