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Sequence-to-sequence models, such as attention-based models in automatic speech recognition (ASR), are typically trained to optimize the cross-entropy criterion which corresponds to improving the log-likelihood of the data. However, system…
Clustering of single-cell RNA sequencing (scRNA-seq) datasets can give key insights into the biological functions of cells. Therefore, it is not surprising that network-based community detection methods (one of the better clustering…
When assessing the causal effect of a binary exposure using observational data, confounder imbalance across exposure arms must be addressed. Matching methods, including propensity score-based matching, can be used to deconfound the causal…
Certifiable, adaptive uncertainty estimates for unknown quantities are an essential ingredient of sequential decision-making algorithms. Standard approaches rely on problem-dependent concentration results and are limited to a specific…
CLIP-seq methods are valuable techniques to experimentally determine transcriptome-wide binding sites of RNA-binding proteins. Despite the constant improvement of such techniques (e.g. eCLIP), the results are affected by various types of…
This paper proposes a semi-sequential probabilistic model (SSP) that applies an additional short term memory to enhance the performance of the probabilistic indoor localization. The conventional probabilistic methods normally treat the…
Recent advancements in speech synthesis have enabled large language model (LLM)-based systems to perform zero-shot generation with controllable content, timbre, speaker identity, and emotion through input prompts. As a result, these models…
In comparative studies of progressive diseases, such as randomized controlled trials (RCTs), the mean Change From Baseline (CFB) of a continuous outcome at a pre-specified follow-up time across subjects in the target population is a…
We consider one of the most basic multiple testing problems that compares expectations of multivariate data among several groups. As a test statistic, a conventional (approximate) $t$-statistic is considered, and we determine its rejection…
In this paper, several works are proposed to address practical challenges for deploying RNN Transducer (RNN-T) based speech recognition system. These challenges are adapting a well-trained RNN-T model to a new domain without collecting the…
All pairs similarity search is a problem where a set of data objects is given and the task is to find all pairs of objects that have similarity above a certain threshold for a given similarity measure-of-interest. When the number of points…
Propensity Score Matching (PSM) is an useful method to reduce the impact ofTreatment - Selection Bias in the estimation of causal effects in observational studies. After matching, the PSM significantly reduces the sample under…
The distribution of single Stop Signal Reaction Times (SSRT) in the stop signal task (SST) as a measurement of the latency of the unobservable stopping process has been modeled with a nonparametric method by Hans Colonius (1990) and with a…
Clinical trials are essential to drug development but time-consuming, costly, and prone to failure. Accurate trial outcome prediction based on historical trial data promises better trial investment decisions and more trial success. Existing…
Logs generated by large-scale software systems provide crucial information for engineers to understand the system status and diagnose problems of the systems. Log parsing, which converts raw log messages into structured data, is the first…
Response-adaptive randomization (RAR) has been studied extensively in conventional, single-stage clinical trials, where it has been shown to yield ethical and statistical benefits, especially in trials with many treatment arms. However, RAR…
We present and evaluate Spectrum-Based Log Diagnosis (SBLD), a method to help developers quickly diagnose problems found in complex integration and deployment runs. Inspired by Spectrum-Based Fault Localization, SBLD leverages the…
Researchers faced with a sequence of candidate model specifications must often choose the best specification that does not violate a testable identification assumption. One option in this scenario is sequential specification tests:…
In this paper we consider the problem of detecting statistically significant sequential patterns in multi-neuronal spike trains. These patterns are characterized by ordered sequences of spikes from different neurons with specific delays…
This work is devoted to investigating the evolution of concentration in a genetic regulation system, when the synthesis reaction rate is under additive and multiplicative asymmetric stable L\'evy fluctuations. By focusing on the impact of…