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With the effective application of deep learning in computer vision, breakthroughs have been made in the research of super-resolution images reconstruction. However, many researches have pointed out that the insufficiency of the neural…

Image and Video Processing · Electrical Eng. & Systems 2021-06-11 Yibo Guo , Haidi Wang , Yiming Fan , Shunyao Li , Mingliang Xu

Position emission tomography (PET) is widely used in clinics and research due to its quantitative merits and high sensitivity, but suffers from low signal-to-noise ratio (SNR). Recently convolutional neural networks (CNNs) have been widely…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Se-In Jang , Tinsu Pan , Ye Li , Pedram Heidari , Junyu Chen , Quanzheng Li , Kuang Gong

In the field of medical image analysis, there is a substantial need for high-resolution (HR) images to improve diagnostic accuracy. However, it is a challenging task to obtain HR medical images, as it requires advanced instruments and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-25 Alireza Aghelan , Modjtaba Rouhani

Tau positron emission tomography (PET) is a critical diagnostic modality for Alzheimer's disease (AD) because it visualizes and quantifies neurofibrillary tangles, a hallmark of AD pathology. However, its widespread clinical adoption is…

Image and Video Processing · Electrical Eng. & Systems 2025-12-19 Jin Young Kim , Jeremy Hudson , Jeongchul Kim , Qing Lyu , Christopher T. Whitlow

Training computer-vision related algorithms on medical images for disease diagnosis or image segmentation is difficult in large part due to privacy concerns. For this reason, generative image models are highly sought after to facilitate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-02 Robert V. Bergen , Jean-Francois Rajotte , Fereshteh Yousefirizi , Arman Rahmim , Raymond T. Ng

One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Anthony DiSpirito , Daiwei Li , Tri Vu , Maomao Chen , Dong Zhang , Jianwen Luo , Roarke Horstmeyer , Junjie Yao

Low-dose CT (LDCT) imaging is desirable in many clinical applications to reduce X-ray radiation dose to patients. Inspired by deep learning (DL), a recent promising direction of model-based iterative reconstruction (MBIR) methods for LDCT…

Image and Video Processing · Electrical Eng. & Systems 2021-02-18 Qiaoqiao Ding , Yuesong Nan , Hao Gao , Hui Ji

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Porous media are ubiquitous in both nature and engineering applications, thus their modelling and understanding is of vital importance. In contrast to direct acquisition of three-dimensional (3D) images of such medium, obtaining its…

Image and Video Processing · Electrical Eng. & Systems 2019-09-25 Junxi Feng , Xiaohai He , Qizhi Teng , Chao Ren , Honggang Chen , Yang Li

Low-dose computed tomography (LDCT) reduces radiation exposure but suffers from image artifacts and loss of detail due to quantum and electronic noise, potentially impacting diagnostic accuracy. Transformer combined with diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qiqing Liu , Guoquan Wei , Zekun Zhou , Yiyang Wen , Liu Shi , Qiegen Liu

Fluorodeoxyglucose positron emission tomography (FDG-PET) imaging based 3D topographic brain glucose metabolism patterns from normal controls (NC) and individuals with dementia of Alzheimer's type (DAT) are used to train a novel multi-scale…

Ultra low radiation dose in X-ray Computed Tomography (CT) is an important clinical objective in order to minimize the risk of carcinogenesis. Compressed Sensing (CS) enables significant reductions in radiation dose to be achieved by…

The integration of multimodal medical imaging can provide complementary and comprehensive information for the diagnosis of Alzheimer's disease (AD). However, in clinical practice, since positron emission tomography (PET) is often missing,…

Computational Engineering, Finance, and Science · Computer Science 2024-12-03 Fuyou Mao , Lixin Lin , Ming Jiang , Dong Dai , Chao Yang , Hao Zhang , Yan Tang

Positron Emission Tomography using 2-[18F]-2deoxy-D-glucose as radiotracer (FDG-PET) is currently one of the most frequently applied functional imaging methods in clinical applications. The interpretation of FDG-PET data requires…

Tissues and Organs · Quantitative Biology 2020-01-22 Michele Piana , Giacomo Caviglia , Sara Sommariva

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

Single-bed whole-body positron emission tomography based on resistive plate chamber detectors (RPC-PET) has been proposed for human studies, as a complementary resource to scintillator-based PET scanners. The purpose of this work is mainly…

By integrating the generative strengths of diffusion models with the representation capabilities of frequency-domain attention, DFAM effectively enhances reconstruction performance under low-SNR condi-tions. Experimental results demonstrate…

Medical Physics · Physics 2025-07-25 Xin Xie , Yu Guan , Zhuoxu Cui , Dong Liang , Qiegen Liu

Accurate quantification of cerebral blood flow (CBF) is essential for the diagnosis and assessment of cerebrovascular diseases such as Moyamoya, carotid stenosis, aneurysms, and stroke. Positron emission tomography (PET) is currently…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Ramy Hussein , Moss Zhao , David Shin , Jia Guo , Kevin T. Chen , Rui D. Armindo , Guido Davidzon , Michael Moseley , Greg Zaharchuk

Dynamic positron emission tomography (PET) reconstruction often presents high noise due to the use of short duration frames to describe the kinetics of the radiotracer. Here we introduce a new method to calculate a kernel matrix to be used…

Medical Physics · Physics 2026-01-01 Alan Miranda , Steven Staelens

The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…