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Sclera segmentation is crucial for developing automatic eye-related medical computer-aided diagnostic systems, as well as for personal identification and verification, because the sclera contains distinct personal features. Deep…

Computer Vision and Pattern Recognition · Computer Science 2025-01-15 Guanjun Wang , Lu Wang , Ning Niu , Qiaoyi Yao , Yixuan Wang , Sufen Ren , Shengchao Chen

Clinical decision-making in oncology involves multimodal data such as radiology scans, molecular profiling, histopathology slides, and clinical factors. Despite the importance of these modalities individually, no deep learning framework to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-02 Nathaniel Braman , Jacob W. H. Gordon , Emery T. Goossens , Caleb Willis , Martin C. Stumpe , Jagadish Venkataraman

Glaucoma is a progressive optic neuropathy characterized by structural damage to the optic nerve head and functional changes in the visual field. Detecting glaucoma early is crucial to preventing loss of eyesight. However, medical datasets…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Youssof Nawar , Nouran Soliman , Moustafa Wassel , Mohamed ElHabebe , Noha Adly , Marwan Torki , Ahmed Elmassry , Islam Ahmed

Optic nerve head (ONH) detection has been a crucial area of study in ophthalmology for years. However, the significant discrepancy between fundus image datasets, each generated using a single type of fundus camera, poses challenges to the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Jiayi Wang , Yi-An Mao , Xiaoyu Ma , Sicen Guo , Yuting Shao , Xiao Lv , Wenting Han , Mark Christopher , Linda M. Zangwill , Yanlong Bi , Rui Fan

Recent large vision-language models such as CLIP have shown remarkable out-of-distribution (OOD) detection and generalization performance. However, their zero-shot in-distribution (ID) accuracy is often limited for downstream datasets.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Yifei Ming , Yixuan Li

Deep learning-based segmentation techniques have shown remarkable performance in brain segmentation, yet their success hinges on the availability of extensive labeled training data. Acquiring such vast datasets, however, poses a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Jihoon Cho , Suhyun Ahn , Beomju Kim , Hyungjoon Bae , Xiaofeng Liu , Fangxu Xing , Kyungeun Lee , Georges Elfakhri , Van Wedeen , Jonghye Woo , Jinah Park

Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, these broad categories typically lack prognostic value, and…

Recent studies suggest that early stages of diabetic retinopathy (DR) can be diagnosed by monitoring vascular changes in the deep vascular complex. In this work, we investigate a novel method for automated DR grading based on optical…

Image and Video Processing · Electrical Eng. & Systems 2022-12-22 Linus Kreitner , Ivan Ezhov , Daniel Rueckert , Johannes C. Paetzold , Martin J. Menten

Recent advancements in pre-trained vision-language models, such as CLIP, have enabled the segmentation of arbitrary concepts solely from textual inputs, a process commonly referred to as open-vocabulary semantic segmentation (OVS). However,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Kunyang Han , Yong Liu , Jun Hao Liew , Henghui Ding , Yunchao Wei , Jiajun Liu , Yitong Wang , Yansong Tang , Yujiu Yang , Jiashi Feng , Yao Zhao

Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

Computer-assisted quantitative analysis on Giga-pixel pathology images has provided a new avenue in histology examination. The innovations have been largely focused on cancer pathology (i.e., tumor segmentation and characterization). In…

Image and Video Processing · Electrical Eng. & Systems 2022-03-24 Ruining Deng , Quan Liu , Can Cui , Zuhayr Asad , Haichun Yang , Yuankai Huo

Objective: To develop an explainable multimodal large language model (MM-LLM) that (1) screens optic nerve head (ONH) OCT circle scans for quality and (2) generates structured clinical reports that include glaucoma diagnosis and sector-wise…

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

We have developed and trained a convolutional neural network to automatically and simultaneously segment optic disc, fovea and blood vessels. Fundus images were normalised before segmentation was performed to enforce consistency in…

Computer Vision and Pattern Recognition · Computer Science 2017-02-03 Jen Hong Tan , U. Rajendra Acharya , Sulatha V. Bhandary , Kuang Chua Chua , Sobha Sivaprasad

The early diagnosis and screening of glaucoma are important for patients to receive treatment in time and maintain eyesight. Nowadays, deep learning (DL) based models have been successfully used for computer-aided diagnosis (CAD) of…

Image and Video Processing · Electrical Eng. & Systems 2021-08-10 Yiming Bao , Jun Wang , Tong Li , Linyan Wang , Jianwei Xu , Juan Ye , Dahong Qian

Accurate isolation and quantification of intraocular dimensions in the anterior segment (AS) of the eye using optical coherence tomography (OCT) images is important in the diagnosis and treatment of many eye diseases, especially angle…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Tan Hung Pham , Sripad Krishna Devalla , Aloysius Ang , Soh Zhi Da , Alexandre H. Thiery , Craig Boote , Ching-Yu Cheng , Victor Koh , Michael J. A. Girard

In recent years, deep learning based methods have shown success in essential medical image analysis tasks such as segmentation. Post-processing and refining the results of segmentation is a common practice to decrease the misclassifications…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Ufuk Demir , Atahan Ozer , Yusuf H. Sahin , Gozde Unal

This paper focuses on a significant yet challenging task: out-of-distribution detection (OOD detection), which aims to distinguish and reject test samples with semantic shifts, so as to prevent models trained on in-distribution (ID) data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Xiang Fang , Arvind Easwaran , Blaise Genest , Ponnuthurai Nagaratnam Suganthan

Analyzing the cone photoreceptor pattern in images obtained from the living human retina using quantitative methods can be crucial for the early detection and management of various eye conditions. Confocal adaptive optics scanning light…

Image and Video Processing · Electrical Eng. & Systems 2024-12-23 Mikhail Kulyabin , Aline Sindel , Hilde Pedersen , Stuart Gilson , Rigmor Baraas , Andreas Maier

In this paper, we propose a novel selection strategy for contrastive learning for medical images. On natural images, contrastive learning uses augmentations to select positive and negative pairs for the contrastive loss. However, in the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Kiran Kokilepersaud , Mohit Prabhushankar , Ghassan AlRegib , Stephanie Trejo Corona , Charles Wykoff