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Methods are lacking to handle the problem of survival analysis in the presence of an interval-censored covariate, specifically the case in which the conditional hazard of the primary event of interest depends on the occurrence of a…

We present a new joint longitudinal and survival model aimed at estimating the association between the risk of an event and the change in and history of a biomarker that is repeatedly measured over time. We use cubic B-splines models for…

Applications · Statistics 2009-10-12 Elizabeth R. Brown

Domain shift in histopathology, often caused by differences in acquisition processes or data sources, poses a major challenge to the generalization ability of deep learning models. Existing methods primarily rely on modeling statistical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Kieu-Anh Truong Thi , Huy-Hieu Pham , Duc-Trong Le

Big longitudinal observational medical data potentially hold a wealth of information and have been recognised as potential sources for gaining new drug safety knowledge. Unfortunately there are many complexities and underlying issues when…

Artificial Intelligence · Computer Science 2016-07-22 Jenna Marie Reps , Jonathan M. Garibaldi , Uwe Aickelin , Jack E. Gibson , Richard B. Hubbard

Microbial identification is a central issue in microbiology, in particular in the fields of infectious diseases diagnosis and industrial quality control. The concept of species is tightly linked to the concept of biological and clinical…

Machine Learning · Statistics 2015-06-25 Kévin Vervier , Pierre Mahé , Jean-Baptiste Veyrieras , Jean-Philippe Vert

Recent years have seen many advances in methods for causal structure learning from data. The empirical assessment of such methods, however, is much less developed. Motivated by this gap, we pose the following question: how can one assess,…

Methodology · Statistics 2020-06-30 Marco F. Eigenmann , Sach Mukherjee , Marloes H. Maathuis

Objective: To characterize stigma dimensions, social, and related behavioral circumstances in people living with HIV(PLWHs) seeking care, using NLP methods applied to a large collection of EHR clinical notes from a large integrated health…

Machine Learning · Computer Science 2025-09-15 Ziyi Chen , Yiyang Liu , Mattia Prosperi , Krishna Vaddiparti , Robert L Cook , Jiang Bian , Yi Guo , Yonghui Wu

We often seek to estimate the impact of an exposure naturally occurring or randomly assigned at the cluster-level. For example, the literature on neighborhood determinants of health continues to grow. Likewise, community randomized trials…

Methodology · Statistics 2021-07-08 Laura B. Balzer , Wenjing Zheng , Mark J. van der Laan , Maya L. Petersen

Background: Sequential positivity is often a necessary assumption for drawing causal inferences, such as through marginal structural modeling. Unfortunately, verification of this assumption can be challenging because it usually relies on…

The discovery of discriminatory bias in human or automated decision making is a task of increasing importance and difficulty, exacerbated by the pervasive use of machine learning and data mining. Currently, discrimination discovery largely…

Computers and Society · Computer Science 2019-11-05 Bilal Qureshi , Faisal Kamiran , Asim Karim , Salvatore Ruggieri , Dino Pedreschi

For time-to-event data with finitely many competing risks, the proportional hazards model has been a popular tool for relating the cause-specific outcomes to covariates [Prentice et al. Biometrics 34 (1978) 541--554]. This article studies…

Statistics Theory · Mathematics 2009-03-04 Yanqing Sun , Peter B. Gilbert , Ian W. McKeague

A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for…

In clinical trials, principal stratification analysis is commonly employed to address the issue of truncation by death, where a subject dies before the outcome can be measured. However, in practice, many survivor outcomes may remain…

Methodology · Statistics 2025-07-08 Wei Li , Yuan Liu , Shanshan Luo , Zhi Geng

Micro-randomized trials are commonly conducted for optimizing mobile health interventions such as push notifications for behavior change. In analyzing such trials, causal excursion effects are often of primary interest, and their estimation…

Methodology · Statistics 2024-08-19 Yihan Bao , Lauren Bell , Elizabeth Williamson , Claire Garnett , Tianchen Qian

Membership inference attacks (MIA) can reveal whether a particular data point was part of the training dataset, potentially exposing sensitive information about individuals. This article provides theoretical guarantees by exploring the…

Machine Learning · Statistics 2025-10-08 Eric Aubinais , Elisabeth Gassiat , Pablo Piantanida

The coronavirus disease (COVID-19) has spread worldwide with an unprecedented impact on society. In the Philippines, several interventions such as mobility restrictions for different age groups and vaccination prioritization programs have…

Quantitative Methods · Quantitative Biology 2023-02-10 Roel F. Ceballos

Latent variables may lead to spurious relationships that can be misinterpreted as causal relationships. In Bayesian Networks (BNs), this challenge is known as learning under causal insufficiency. Structure learning algorithms that assume…

Machine Learning · Computer Science 2020-08-19 Kiattikun Chobtham , Anthony C. Constantinou

Feature selection is a crucial preprocessing step in data analytics and machine learning. Classical feature selection algorithms select features based on the correlations between predictive features and the class variable and do not attempt…

Machine Learning · Computer Science 2019-11-19 Kui Yu , Xianjie Guo , Lin Liu , Jiuyong Li , Hao Wang , Zhaolong Ling , Xindong Wu

Scientists often want to learn about cause and effect from hierarchical data, collected from subunits nested inside units. Consider students in schools, cells in patients, or cities in states. In such settings, unit-level variables (e.g.…

Methodology · Statistics 2024-06-27 Eli N. Weinstein , David M. Blei

Machine Learning (ML) has become an integral aspect of many real-world applications. As a result, the need for responsible machine learning has emerged, focusing on aligning ML models to ethical and social values, while enhancing their…

Machine Learning · Computer Science 2024-02-06 Raha Moraffah , Paras Sheth , Saketh Vishnubhatla , Huan Liu
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