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We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. In previous papers, we have established well-posedness of this problem and…

Analysis of PDEs · Mathematics 2024-02-06 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model…

Analysis of PDEs · Mathematics 2020-06-30 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

A mutualist model with nonlocal diffusions and a free boundary is first considered. We prove that this problem has a unique solution defined $t\ge0$, and its dynamics are governed by a spreading-vanishing dichotomy. Some criteria for…

Analysis of PDEs · Mathematics 2021-10-28 Lei Li , Mingxin Wang

In this paper we study a mass-constrained free boundary problem modeling cell polarization, in the regime where the mass is small. In the generic case of a signal with nondegenerate maxima, we prove that the solution converges locally to a…

Analysis of PDEs · Mathematics 2026-05-06 Sebastián Flores Sepúlveda , Barbara Niethammer , Juan J. L. Velázquez

We consider a coupled bulk-surface system of partial differential equations with nonlinear coupling modelling receptor-ligand dynamics. The model arises as a simplification of a mathematical model for the reaction between cell surface…

Analysis of PDEs · Mathematics 2016-11-08 Charles M. Elliott , Thomas Ranner , Chandrasekhar Venkataraman

We derive various novel free boundary problems as limits of a coupled bulk-surface reaction-diffusion system modelling ligand-receptor dynamics on evolving domains. These limiting free boundary problems may be formulated as Stefan-type…

Analysis of PDEs · Mathematics 2024-07-24 Amal Alphonse , Diogo Caetano , Charles M. Elliott , Chandrasekhar Venkataraman

We consider an elliptic-parabolic free boundary problem that models the fluid flow through a partially saturated porous medium. The free boundary arises as the interface separating the saturated and unsaturated regions. Our main goal is to…

Analysis of PDEs · Mathematics 2025-08-20 Dennis Kriventsov , María Soria-Carro

In this work, we investigate the dynamics of a non-local model describing spontaneous cell polarisation. It consists in a drift-diffusion equation set in the half-space, with the coupling involving the trace value on the boundary. We…

Analysis of PDEs · Mathematics 2011-05-24 Vincent Calvez , Rhoda Hawkins , Nicolas Meunier , Raphael Voituriez

In this paper, we establish the existence of a positive, bounded solution for a class of parabolic partial differential equations with nonlinear boundary conditions, where the boundary conditions depend on the solution on the boundary at a…

Dynamical Systems · Mathematics 2025-07-15 Gangadhara Boregowda , Michael R. Lindstrom

We consider one-dimensional parabolic free boundary value problem with a nonlocal (integro-differential) condition on the free boundary. Results on $C^m$-regularity of the free boundary are obtained. In particular, a necessary and…

Analysis of PDEs · Mathematics 2013-08-21 Rossitza Semerdjieva

This paper deals with the long-time behavior of solutions of nonlinear reaction-diffusion equations describing formation of morphogen gradients, the concentration fields of molecules acting as spatial regulators of cell differentiation in…

Analysis of PDEs · Mathematics 2013-03-27 Peter V. Gordon , Cyrill B. Muratov

We investigate the finite time stability property of one-dimensional nonautonomous initial boundary value problems for linear decoupled hyperbolic systems with nonlinear boundary conditions. We establish sufficient and necessary conditions…

Analysis of PDEs · Mathematics 2025-12-10 Irina Kmit

The dynamical and stationary behaviors of a fourth-order evolution equation with clamped boundary conditions and a singular nonlocal reaction term, which is coupled to an elliptic free boundary problem on a non-smooth domain, are…

Analysis of PDEs · Mathematics 2013-08-29 Philippe Laurencot , Christoph Walker

This paper studies asymptotic behavior of solutions of a free boundary problem modeling the growth of tumors with two species of cells: proliferating cells and quiecent cells. In previous literatures it has been proved that this problem has…

Analysis of PDEs · Mathematics 2013-03-18 Shangbin Cui

A class of diffusion driven Free Boundary Problems is considered which is characterized by the initial onset of a phase and by an explicit kinematic condition for the evolution of the free boundary. By a domain fixing change of variables it…

Analysis of PDEs · Mathematics 2018-08-14 Patrick Guidotti

We investigate positive steady states of an indefinite superlinear reaction-diffusion equation arising from population dynamics, coupled with a nonlinear boundary condition. Both the equation and the boundary condition depend upon a…

Analysis of PDEs · Mathematics 2015-09-29 Humberto Ramos Quoirin , Kenichiro Umezu

We are concerned with the global bifurcation analysis of positive solutions to free boundary problems arising in plasma physics. We show that in general, in the sense of domain variations, the following alternative holds: either the shape…

Analysis of PDEs · Mathematics 2021-12-13 Daniele Bartolucci , Yeyao Hu , Aleks Jevnikar , Wen Yang

We study a class of free boundary problems of ecological models with nonlocal and local diffusions, which are natural extensions of free boundary problems of reaction diffusion systems in there local diffusions are used to describe the…

Analysis of PDEs · Mathematics 2019-09-17 Jianping Wang , Mingxin Wang

In this paper, we study a free boundary problem for a class of nonlinear nonautonomous size structured population model. Using the comparison principle and upper lower solution methods, we establish the existence of the solution for such…

Analysis of PDEs · Mathematics 2017-11-10 Wenbin Lv , Shaohua Wu

The Cahn--Hilliard equation is one of the most common models to describe phase segregation processes in binary mixtures. In recent times, various dynamic boundary conditions have been introduced to model interactions of the materials with…

Analysis of PDEs · Mathematics 2021-10-12 Patrik Knopf , Andrea Signori
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