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We consider the asymptotic properties of the Synthetic Control (SC) estimator when both the number of pre-treatment periods and control units are large. If potential outcomes follow a linear factor model, we provide conditions under which…

Econometrics · Economics 2020-05-27 Bruno Ferman

The synthpop package for R https://www.synthpop.org.uk provides tools to allow data custodians to create synthetic versions of confidential microdata that can be distributed with fewer restrictions than the original. The synthesis can be…

Computation · Statistics 2021-11-16 Gillian M Raab , Beata Nowok , Chris Dibben

The synthetic control method (SCM) is widely used for constructing the counterfactual of a treated unit based on data from control units in a donor pool. Allowing the donor pool contains more control units than time periods, we propose a…

Econometrics · Economics 2026-05-19 Chengwang Liao , Zhentao Shi , Yapeng Zheng

Mixed-frequency data, where variables are observed at different temporal resolutions, commonly occur in economic and financial studies. Classical synthetic control methods (SCM) are ill-suited for such data, often necessitating aggregation…

Methodology · Statistics 2026-05-13 Lu Zhang , Shijin Gong , Xinyu Zhang

The importance of uncertainty quantification is increasingly recognized in the diverse field of machine learning. Accurately assessing model prediction uncertainty can help provide deeper understanding and confidence for researchers and…

Machine Learning · Computer Science 2024-12-03 Tianyi Chen , Yingzhou Lu , Nan Hao , Yuanyuan Zhang , Capucine Van Rechem , Jintai Chen , Tianfan Fu

The Synthetic Control method has pioneered a class of powerful data-driven techniques to estimate the counterfactual reality of a unit from donor units. At its core, the technique involves a linear model fitted on the pre-intervention…

Artificial Intelligence · Computer Science 2022-11-28 Bhishma Dedhia , Roshini Balasubramanian , Niraj K. Jha

We present a robust generalization of the synthetic control method for comparative case studies. Like the classical method, we present an algorithm to estimate the unobservable counterfactual of a treatment unit. A distinguishing feature of…

Econometrics · Economics 2017-11-21 Muhammad Jehangir Amjad , Devavrat Shah , Dennis Shen

The synthetic control method has become a widely popular tool to estimate causal effects with observational data. Despite this, inference for synthetic control methods remains challenging. Often, inferential results rely on linear factor…

Methodology · Statistics 2024-07-09 Ignacio Martinez , Jaume Vives-i-Bastida

Models used for control design are, to some degree, uncertain. Model uncertainty must be accounted for to ensure the robustness of the closed-loop system. $\mu$-analysis and $\mu$-synthesis methods allow for the analysis and design of…

Systems and Control · Electrical Eng. & Systems 2025-11-19 Timothy Everett Adams , Steven Dahdah , James Richard Forbes

This paper presents a method to identify an uncertain linear time-invariant (LTI) prediction model for tube-based Robust Model Predictive Control (RMPC). The uncertain model is determined from a given state-input dataset by formulating and…

Systems and Control · Electrical Eng. & Systems 2023-10-10 Sampath Kumar Mulagaleti , Alberto Bemporad , Mario Zanon

We present a new estimator for causal effects with panel data that builds on insights behind the widely used difference in differences and synthetic control methods. Relative to these methods we find, both theoretically and empirically,…

Methodology · Statistics 2025-09-22 Dmitry Arkhangelsky , Susan Athey , David A. Hirshberg , Guido W. Imbens , Stefan Wager

Data following an interval structure are increasingly prevalent in many scientific applications. In medicine, clinical events are often monitored between two clinical visits, making the exact time of the event unknown and generating…

Methodology · Statistics 2025-04-01 Carlos García Meixide , Michael R. Kosorok , Marcos Matabuena

Accurate quantification of model uncertainty has long been recognized as a fundamental requirement for trusted AI. In regression tasks, uncertainty is typically quantified using prediction intervals calibrated to an ad-hoc operating point,…

Machine Learning · Computer Science 2023-10-06 Jiri Navratil , Benjamin Elder , Matthew Arnold , Soumya Ghosh , Prasanna Sattigeri

We develop a new approach for quantifying uncertainty in finite populations, by using design distributions to calibrate sensitivity parameters in finite population identified sets. This yields uncertainty intervals that can be interpreted…

Econometrics · Economics 2026-05-12 Brendan Kline , Matthew A. Masten

Randomized clinical trials are the gold standard when estimating the average treatment effect. However, they are usually not a random sample from the real-world population because of the inclusion/exclusion rules. Meanwhile, observational…

Methodology · Statistics 2024-12-11 Kuan Jiang , Wenjie Hu , Shu Yang , Xinxing Lai , Xiaohua Zhou

Improper pain management can lead to severe physical or mental consequences, including suffering, and an increased risk of opioid dependency. Assessing the presence and severity of pain is imperative to prevent such outcomes and determine…

Machine Learning · Computer Science 2023-11-30 Burcu Ozek , Zhenyuan Lu , Srinivasan Radhakrishnan , Sagar Kamarthi

The development and generation of synthetic data are becoming increasingly vital in the field of statistical disclosure control. The PSInference package provides tools to perform exact inferential analysis on singly imputed synthetic data…

Methodology · Statistics 2025-03-20 Ricardo Moura , Mina Norouzirad , Vitor Augusto , Miguel Fonseca

In personalized medicine, the ability to predict and optimize treatment outcomes across various time frames is essential. Additionally, the ability to select cost-effective treatments within specific budget constraints is critical. Despite…

Machine Learning · Computer Science 2024-10-14 Thomas Schwarz , Cecilia Casolo , Niki Kilbertus

Explainable AI (xAI) interventions aim to improve interpretability for complex black-box models, not only to improve user trust but also as a means to extract scientific insights from high-performing predictive systems. In molecular…

Machine Learning · Computer Science 2025-04-04 Jonas Teufel , Annika Leinweber , Pascal Friederich

A/B tests, also known as randomized controlled experiments (RCTs), are the gold standard for evaluating the impact of new policies, products, or decisions. However, these tests can be costly in terms of time and resources, potentially…

Machine Learning · Statistics 2025-01-03 Shima Nassiri , Mohsen Bayati , Joe Cooprider