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Microtubules are stiff filamentary proteins that constitute an important component of the cytoskeleton of cells. These are known to exhibit a dynamic instability. A steadily growing microtubule can suddenly start depolymerizing very…

Statistical Mechanics · Physics 2009-11-10 Pankaj Kumar Mishra , Ambarish Kunwar , Sutapa Mukherji , Debashish Chowdhury

Certain regulatory proteins influence the polymerization dynamics of microtubules by inducing catastrophe with a rate that depends on the microtubule length. Using a discrete formulation, here we show that, for a catastrophe rate…

Biological Physics · Physics 2012-08-27 Vandana Yadav , Sutapa Mukherji

The statistics of polymers advected by a turbulent flow are investigated. To limit the polymer lengths above to coil-stretch transition, a FENE-P type relaxation law is used. The turbulence is modeled by a random strain, delta-correlated in…

Chaotic Dynamics · Physics 2009-11-07 Jean-Luc Thiffeault

We investigate the microtubule polymerization dynamics with catastrophe and rescue events for three different confinement scenarios, which mimic typical cellular environments: (i) The microtubule is confined by rigid and fixed walls, (ii)…

Subcellular Processes · Quantitative Biology 2015-05-12 Björn Zelinski , Nina Müller , Jan Kierfeld

Dimerization and subsequent aggregation of polymers and biopolymers often occur under nonequilibrium conditions. When the initial state of the polymer is not collapsed or the final folded native state, the dynamics of dimerization can…

Soft Condensed Matter · Physics 2024-11-19 Sangita Mondal , Ved Mahajan , Biman Bagchi

A simple stochastic model which describes microtubule dynamics and explicitly takes into account the relevant biochemical processes is presented. The model incorporates binding and unbinding of monomers and random phosphate release inside…

Statistical Mechanics · Physics 2015-05-27 Ranjith Padinhateeri , Anatoly B. Kolomeisky , David Lacoste

In a recent publication [PRL {\bf 81}, 1142 (1998)] it was argued that a randomly forced particle which collides inelastically with a boundary can undergo inelastic collapse and come to rest in a finite time. Here we discuss the survival…

Statistical Mechanics · Physics 2009-10-31 Michael R. Swift , Alan J. Bray

Catastrophic transitions, where a system shifts abruptly between alternate steady states, are a generic feature of many nonlinear systems. Recently these regime shift were suggested as the mechanism underlies many ecological catastrophes,…

Populations and Evolution · Quantitative Biology 2015-06-11 Haim Weissmann , Nadav M. Shnerb

The intermittent transition between slow growth and rapid shrinkage in polymeric assemblies is termed dynamic instability, a feature observed in a variety of biochemically distinct assemblies including microtubules, actin and their…

Soft Condensed Matter · Physics 2015-05-28 Stefano Zapperi , L. Mahadevan

Statistical aspects of the dynamics of chaotic scattering in the classical model of $\alpha$-cluster nuclei are studied. It is found that the dynamics governed by hyperbolic instabilities which results in an exponential decay of the…

Nuclear Theory · Physics 2009-09-25 S. Drożdż , J. Okołowicz , T. Srokowski , A. Budzanowski

We provide a clear energetic insight into the catastrophic nature of the so-called creasing and pull-in instabilities in soft electro-active elastomers. These phenomena are ubiquitous for thin electro-elastic plates and are a major obstacle…

Soft Condensed Matter · Physics 2017-02-22 Giuseppe Zurlo , Michel Destrade , Domenico DeTommasi , Giuseppe Puglisi

The number of allowed configurations of a polymer is reduced by the presence of a repulsive surface resulting in an entropic force between them. We develop a method to calculate the entropic force, and detailed pressure distribution, for…

Statistical Mechanics · Physics 2014-02-11 Yosi Hammer , Yacov Kantor

The uniaxial elastic-plastic deformation process is considered. Mathematical model of this process was built. According to this model all stable static states form the lattice, which is called the delta-lattice.

Materials Science · Physics 2007-05-23 L. N. Maurin , I. S. Tikhomirova

We consider the internal dynamics of the polymer molecule which is injected in the chaotic flow with strong mean shear component. The flow geometry corresponds to the recent experiments on the elastic turbulence (Groisman, Steinberg 2000).…

Chaotic Dynamics · Physics 2007-05-23 K. S. Turitsyn

Dynamic instability of microtubules is considered using frameworks of non-linear thermodynamics and non-equilibrium reaction-diffusion systems. Stochastic assembly/disassembly phases in the polymerization dynamics of microtubules are…

Subcellular Processes · Quantitative Biology 2016-11-15 Eugene Katrukha

A polymer placed in chaotic flow with large mean shear tumbles, making a-periodic flips. We describe the statistics of angular orientation, as well as of tumbling time (separating two subsequent flips) of polymers in this flow. The…

Statistical Mechanics · Physics 2007-05-23 M. Chertkov , I. Kolokolov , V. Lebedev , K. Turitsyn

We classify all possible singularities in the electronic dispersion of two-dimensional systems that occur when the Fermi surface changes topology, using catastrophe theory. For systems with up to seven control parameters (i.e., pressure,…

Strongly Correlated Electrons · Physics 2020-04-01 Anirudh Chandrasekaran , Alex Shtyk , Joseph J. Betouras , Claudio Chamon

The statistics and origin of the first discrete plastic event in a one dislocation dynamics simulation are studied. This is done via a linear stability analysis of the evolving dislocation configuration up to the onset of irreversible…

Materials Science · Physics 2016-09-07 P. M. Derlet , R. Maaß

Several independent observations have suggested that catastrophe transition in microtubules is not a first-order process, as is usually assumed. Recent {\it in vitro} observations by Gardner et al.[ M. K. Gardner et al., Cell {\bf147}, 1092…

Subcellular Processes · Quantitative Biology 2015-07-02 V. Jemseena , Manoj Gopalakrishnan

The tumbling dynamics of individual polymers in semidilute solution is studied by large-scale non-equilibrium mesoscale hydrodynamic simulations. We find that the tumbling time is equal to the non-equilibrium relaxation time of the polymer…

Soft Condensed Matter · Physics 2011-03-21 C. -C. Huang , G. Sutmann , G. Gompper , R. G. Winkler
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