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Related papers: Collaborative analysis of genomic data: vision and…

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Pharmaceutical industry can better leverage its data assets to virtualize drug discovery through a collaborative machine learning platform. On the other hand, there are non-negligible risks stemming from the unintended leakage of…

Cryptography and Security · Computer Science 2022-06-10 Balazs Pejo , Mina Remeli , Adam Arany , Mathieu Galtier , Gergely Acs

Homomorphic encryption, secure multi-party computation, and differential privacy are part of an emerging class of Privacy Enhancing Technologies which share a common promise: to preserve privacy whilst also obtaining the benefits of…

Human-Computer Interaction · Computer Science 2021-01-21 Nitin Agrawal , Reuben Binns , Max Van Kleek , Kim Laine , Nigel Shadbolt

Recent advances in deep generative models have greatly expanded the potential to create realistic synthetic health datasets. These synthetic datasets aim to preserve the characteristics, patterns, and overall scientific conclusions derived…

Machine Learning · Computer Science 2024-07-04 Jennifer A Bartell , Sander Boisen Valentin , Anders Krogh , Henning Langberg , Martin Bøgsted

Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. Modern approaches for data generation based on machine…

Machine Learning · Computer Science 2023-01-11 Chao Yan , Yao Yan , Zhiyu Wan , Ziqi Zhang , Larsson Omberg , Justin Guinney , Sean D. Mooney , Bradley A. Malin

Background: The rapid development and use of generative AI (GenAI) tools in academia presents complex and multifaceted ethical challenges for its users. Earlier research primarily focused on academic integrity concerns related to students'…

Computers and Society · Computer Science 2024-12-16 Sonja Bjelobaba , Lorna Waddington , Mike Perkins , Tomáš Foltýnek , Sabuj Bhattacharyya , Debora Weber-Wulff

Understanding functional organization of genetic information is a major challenge in modern biology. Following the initial publication of the human genome sequence in 2001, advances in high-throughput measurement technologies and efficient…

Machine Learning · Statistics 2011-03-01 Leo Lahti

The digitization of health records has greatly improved the efficiency of the healthcare system and promoted the formulation of related research and policies. However, the widespread application of advanced technologies such as electronic…

Cryptography and Security · Computer Science 2025-02-07 Zhang Si Yuan , Manmeet Mahinderjit Singh

With the rapidly changing technological realm, there is an urgent need to provide and protect the confidentiality of confidential images when stored in a cloud environment. To overcome the security risks associated with single cloud,…

Cryptography and Security · Computer Science 2016-11-24 Dr. Grasha Jacob , Dr. A. Murugan

Today's sequencing technology allows sequencing an individual genome within a few weeks for a fraction of the costs of the original Human Genome project. Genomics labs are faced with dozens of TB of data per week that have to be…

Databases · Computer Science 2009-09-15 Uwe Roehm , Jose Blakeley

Blockchain has the potential to revolutionize the way we store, use, and process data. Information on most blockchains can be viewed by every node hosting the blockchain, which means that most blockchains cannot handle private data.…

Cryptography and Security · Computer Science 2018-10-30 Sabine Bertram , Co-Pierre Georg

Motivated by the growing availability of personal genomics services, we study an information-theoretic privacy problem that arises when sharing genomic data: a user wants to share his or her genome sequence while keeping the genotypes at…

Information Theory · Computer Science 2021-10-18 Fangwei Ye , Hyunghoon Cho , Salim El Rouayheb

The availability of rich and vast data sources has greatly advanced machine learning applications in various domains. However, data with privacy concerns comes with stringent regulations that frequently prohibited data access and data…

Machine Learning · Computer Science 2023-09-28 Dingfan Chen , Raouf Kerkouche , Mario Fritz

In this paper we describe a new technique for the comparison of populations of DNA strands. Comparison is vital to the study of ecological systems, at both the micro and macro scales. Existing methods make use of DNA sequencing and cloning,…

Biomolecules · Quantitative Biology 2008-07-02 Dennis Shasha , Martyn Amos

Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…

We developed a high-performance one-stop system for large-scale genome data analysis with secure secondary use of the data by the data owner and multiple users with different levels of data access control.

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

We propose and apply a novel paradigm for characterization of genome data quality, which quantifies the effects of intentional degradation of quality. The rationale is that the higher the initial quality, the more fragile the genome and the…

Machine Learning · Statistics 2022-10-12 Alan F. Karr , Jason Hauzel , Adam A. Porter , Marcel Schaefer

The projected increase of genotyping in the clinic and the rise of large genomic databases has led to the possibility of using patient medical data to perform genomewide association studies (GWAS) on a larger scale and at a lower cost than…

Quantitative Methods · Quantitative Biology 2016-04-18 Sean Simmons , Cenk Sahinalp , Bonnie Berger

Educators and learners worldwide are embracing the rise of Generative Artificial Intelligence (GenAI) as it reshapes higher education. However, GenAI also raises significant privacy and security concerns, as models and privacy-sensitive…

Human-Computer Interaction · Computer Science 2025-06-26 Bei Yi Ng , Jiarui Li , Xinyuan Tong , Kevin Ye , Gauthami Yenne , Varun Chandrasekaran , Jingjie Li

Synthetic data offers a promising solution to privacy concerns in healthcare by generating useful datasets in a privacy-aware manner. However, although synthetic data is typically developed with the intention of sharing said data, ambiguous…