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Registration of images with pathologies is challenging due to tissue appearance changes and missing correspondences caused by the pathologies. Moreover, mass effects as observed for brain tumors may displace tissue, creating larger…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Xu Han , Zhengyang Shen , Zhenlin Xu , Spyridon Bakas , Hamed Akbari , Michel Bilello , Christos Davatzikos , Marc Niethammer

The recent application of deep learning technologies in medical image registration has exponentially decreased the registration time and gradually increased registration accuracy when compared to their traditional counterparts. Most of the…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Abdullah Nazib , Clinton Fookes , Olivier Salvado , Dimitri Perrin

Complicated image registration is a key issue in medical image analysis, and deep learning-based methods have achieved better results than traditional methods. The methods include ConvNet-based and Transformer-based methods. Although…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Runshi Zhang , Hao Mo , Junchen Wang , Bimeng Jie , Yang He , Nenghao Jin , Liang Zhu

Deformable image registration is crucial for aligning medical images in a nonlinear fashion across different modalities, allowing for precise spatial correspondence between varying anatomical structures. This paper presents NestedMorph, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Gurucharan Marthi Krishna Kumar , Janine Mendola , Amir Shmuel

Multimodal image registration is a very challenging problem for deep learning approaches. Most current work focuses on either supervised learning that requires labelled training scans and may yield models that bias towards annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Mattias P Heinrich , Lasse Hansen

Multi-modal image registration plays a critical role in precision medicine but faces challenges from non-linear intensity relationships and local optima. While deep learning models enable rapid inference, they often suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

As in other areas of medical image analysis, e.g. semantic segmentation, deep learning is currently driving the development of new approaches for image registration. Multi-scale encoder-decoder network architectures achieve state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Lasse Hansen , Mattias P. Heinrich

Surgical navigation based on multimodal image registration has played a significant role in providing intraoperative guidance to surgeons by showing the relative position of the target area to critical anatomical structures during surgery.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Jiazheng Wang , Zeyu Liu , Min Liu , Xiang Chen , Xinyao Yu , Yaonan Wang , Hang Zhang

Deep learning-based image processing is capable of creating highly appealing results. However, it is still widely considered as a "blackbox" transformation. In medical imaging, this lack of comprehensibility of the results is a sensitive…

Image and Video Processing · Electrical Eng. & Systems 2020-05-29 Bernhard Stimpel , Christopher Syben , Franziska Schirrmacher , Philipp Hoelter , Arnd Dörfler , Andreas Maier

This paper presents DeepFLASH, a novel network with efficient training and inference for learning-based medical image registration. In contrast to existing approaches that learn spatial transformations from training data in the high…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Jian Wang , Miaomiao Zhang

Unsupervised deep-learning (DL) models were recently proposed for deformable image registration tasks. In such models, a neural-network is trained to predict the best deformation field by minimizing some dissimilarity function between the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-11 Samah Khawaled , Moti Freiman

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…

Machine Learning · Computer Science 2018-05-04 Ayush Jaiswal , Dong Guo , Cauligi S. Raghavendra , Paul Thompson

Multi-modality medical images can provide relevant or complementary information for a target (organ, tumor or tissue). Registering multi-modality images to a common space can fuse these comprehensive information, and bring convenience for…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Wangbin Ding , Lei Li , Xiahai Zhuang , Liqin Huang

Multi-modality is widely used in medical imaging, because it can provide multiinformation about a target (tumor, organ or tissue). Segmentation using multimodality consists of fusing multi-information to improve the segmentation. Recently,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Tongxue Zhou , Su Ruan , Stéphane Canu

Deformable templates, or atlases, are images that represent a prototypical anatomy for a population, and are often enhanced with probabilistic anatomical label maps. They are commonly used in medical image analysis for population studies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Marianne Rakic , Andrew Hoopes , S. Mazdak Abulnaga , Mert R. Sabuncu , John V. Guttag , Adrian V. Dalca

Deformable image registration is inherently a multi-objective optimization (MOO) problem, requiring a delicate balance between image similarity and deformation regularity. These conflicting objectives often lead to poor optimization…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Yi Zhang , Yidong Zhao , Qian Tao

Image registration aims to establish spatial correspondence across pairs, or groups of images, and is a cornerstone of medical image computing and computer-assisted-interventions. Currently, most deep learning-based registration methods…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Xiang Chen , Nishant Ravikumar , Yan Xia , Alejandro F Frangi

We present a parallel distributed-memory algorithm for large deformation diffeomorphic registration of volumetric images that produces large isochoric deformations (locally volume preserving). Image registration is a key technology in…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-25 Andreas Mang , Amir Gholami , George Biros

Accurate compensation of brain shift is critical for maintaining the reliability of neuronavigation during neurosurgery. While keypoint-based registration methods offer robustness to large deformations and topological changes, they…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Tiago Assis , Ines P. Machado , Benjamin Zwick , Nuno C. Garcia , Reuben Dorent

Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui