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Latent variable models such as the Variational Auto-Encoder (VAE) have become a go-to tool for analyzing biological data, especially in the field of single-cell genomics. One remaining challenge is the interpretability of latent variables…

Genomics · Quantitative Biology 2023-02-20 Romain Lopez , Nataša Tagasovska , Stephen Ra , Kyunghyn Cho , Jonathan K. Pritchard , Aviv Regev

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

Variational auto-encoders (VAEs) are an influential and generally-used class of likelihood-based generative models in unsupervised learning. The likelihood-based generative models have been reported to be highly robust to the…

Machine Learning · Computer Science 2020-10-06 Xuming Ran , Mingkun Xu , Qi Xu , Huihui Zhou , Quanying Liu

Learning disentanglement aims at finding a low dimensional representation which consists of multiple explanatory and generative factors of the observational data. The framework of variational autoencoder (VAE) is commonly used to…

Machine Learning · Computer Science 2023-12-20 Mengyue Yang , Furui Liu , Zhitang Chen , Xinwei Shen , Jianye Hao , Jun Wang

Variational AutoEncoders (VAEs) provide a means to generate representational latent embeddings. Previous research has highlighted the benefits of achieving representations that are disentangled, particularly for downstream tasks. However,…

Computer Vision and Pattern Recognition · Computer Science 2019-11-18 Matthew J. Vowels , Necati Cihan Camgoz , Richard Bowden

The framework of variational autoencoders (VAEs) provides a principled method for jointly learning latent-variable models and corresponding inference models. However, the main drawback of this approach is the blurriness of the generated…

Machine Learning · Computer Science 2020-07-01 Ioannis Gatopoulos , Maarten Stol , Jakub M. Tomczak

Normalizing flows, autoregressive models, variational autoencoders (VAEs), and deep energy-based models are among competing likelihood-based frameworks for deep generative learning. Among them, VAEs have the advantage of fast and tractable…

Machine Learning · Statistics 2021-01-11 Arash Vahdat , Jan Kautz

Learning disentangled and interpretable representations is an important step towards accomplishing comprehensive data representations on the manifold. In this paper, we propose a novel representation learning algorithm which combines the…

Machine Learning · Computer Science 2021-07-13 Fei Ye , Adrian G. Bors

Graph structured data are abundant in the real world. Among different graph types, directed acyclic graphs (DAGs) are of particular interest to machine learning researchers, as many machine learning models are realized as computations on…

Machine Learning · Computer Science 2019-10-30 Muhan Zhang , Shali Jiang , Zhicheng Cui , Roman Garnett , Yixin Chen

Variational autoencoders (VAEs) have received much attention recently as an end-to-end architecture for text generation with latent variables. In this paper, we investigate several multi-level structures to learn a VAE model to generate…

Computation and Language · Computer Science 2019-06-21 Dinghan Shen , Asli Celikyilmaz , Yizhe Zhang , Liqun Chen , Xin Wang , Jianfeng Gao , Lawrence Carin

Despite recent successes in synthesizing faces and bedrooms, existing generative models struggle to capture more complex image types, potentially due to the oversimplification of their latent space constructions. To tackle this issue,…

Machine Learning · Computer Science 2018-03-13 Wenling Shang , Kihyuk Sohn , Yuandong Tian

Variational Autoencoders (VAEs) typically rely on a probabilistic decoder with a predefined likelihood, most commonly an isotropic Gaussian, to model the data conditional on latent variables. While convenient for optimization, this choice…

Machine Learning · Statistics 2025-04-29 Chen Xu , Qiang Wang , Lijun Sun

Deep generative models are reported to be useful in broad applications including image generation. Repeated inference between data space and latent space in these models can denoise cluttered images and improve the quality of inferred…

Machine Learning · Statistics 2017-12-13 Yoshihiro Nagano , Ryo Karakida , Masato Okada

Integrating symbolic knowledge and data-driven learning algorithms is a longstanding challenge in Artificial Intelligence. Despite the recognized importance of this task, a notable gap exists due to the discreteness of symbolic…

Artificial Intelligence · Computer Science 2024-05-24 Gaia Saveri , Laura Nenzi , Luca Bortolussi , Jan Křetínský

Variational autoencoders (VAEs) are a powerful class of deep generative latent variable model for unsupervised representation learning on high-dimensional data. To ensure computational tractability, VAEs are often implemented with a…

Machine Learning · Computer Science 2020-06-09 Alex Campbell , Pietro Liò

Autonomous driving presents a complex challenge, which is usually addressed with artificial intelligence models that are end-to-end or modular in nature. Within the landscape of modular approaches, a bio-inspired neural circuit policy model…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Anass Bairouk , Mirjana Maras , Simon Herlin , Alexander Amini , Marc Blanchon , Ramin Hasani , Patrick Chareyre , Daniela Rus

Variational Autoencoder (VAE)-based generative models offer flexible representation learning by incorporating meta-priors, general premises considered beneficial for downstream tasks. However, the incorporated meta-priors often involve…

Machine Learning · Computer Science 2023-02-27 Nao Nakagawa , Ren Togo , Takahiro Ogawa , Miki Haseyama

Variational Autoencoder (VAE), a simple and effective deep generative model, has led to a number of impressive empirical successes and spawned many advanced variants and theoretical investigations. However, recent studies demonstrate that,…

Machine Learning · Computer Science 2019-01-08 Xuezhe Ma , Chunting Zhou , Eduard Hovy

We propose an approach to symbolic regression based on a novel variational autoencoder for generating hierarchical structures, HVAE. It combines simple atomic units with shared weights to recursively encode and decode the individual nodes…

Machine Learning · Computer Science 2023-09-12 Sebastian Mežnar , Sašo Džeroski , Ljupčo Todorovski

Although variational autoencoders (VAEs) represent a widely influential deep generative model, many aspects of the underlying energy function remain poorly understood. In particular, it is commonly believed that Gaussian encoder/decoder…

Machine Learning · Computer Science 2019-10-31 Bin Dai , David Wipf
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