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As molecular scientists have made progress in their ability to engineer nano-scale molecular structure, we are facing new challenges in our ability to engineer molecular dynamics (MD) and flexibility. Dynamics at the molecular scale differs…

Simulating drug binding and unbinding is a challenge, as the rugged energy landscapes that separate bound and unbound states require extensive sampling that consumes significant computational resources. Here, we describe the use of…

Molecular dynamics (MD) simulations are a crucial computational tool for researchers to understand and engineer molecular structure and function in areas such as drug discovery, protein engineering, and material design. Despite their…

We describe a framework for interactive molecular dynamics in a multiuser virtual reality environment, combining rigorous cloud-mounted physical atomistic simulation with commodity virtual reality hardware, which we have made accessible to…

The ability to precisely visualize the atomic geometry of the interactions between a drug and its protein target in structural models is critical in predicting the correct modifications in previously identified inhibitors to create more…

Biomolecules · Quantitative Biology 2018-08-14 Erick Martins Ratamero , Dom Bellini , Christopher G. Dowson , Rudolf A. Roemer

Molecular dynamics (MD) simulations provide crucial insight into molecular interactions and biomolecular function. With interactive MD simulations in VR (iMD-VR), chemists can now interact with these molecular simulations in real-time. Our…

Human-Computer Interaction · Computer Science 2024-09-13 Rhoslyn Roebuck Williams , Jonathan Barnoud , Luis Toledo , Till Holzapfel , David R. Glowacki

Virtual Reality (VR) is increasingly being recognized for its educational potential and as an effective way to convey new knowledge to people, it supports interactive and collaborative activities. Affordable VR powered by mobile…

Human-Computer Interaction · Computer Science 2018-09-25 Tiffany Leung , Farhana Zulkernine , Haruna Isah

We contribute MolecuSense, a virtual version of a physical molecule construction kit, based on visualization in Virtual Reality (VR) and interaction with force-feedback gloves. Targeting at chemistry education, our goal is to make virtual…

Human-Computer Interaction · Computer Science 2022-11-14 Patrick Gebhardt , Xingyao Yu , Andreas Köhn , Michael Sedlmair

Virtual reality (VR) is increasingly used to enhance the ecological validity of motor control and learning studies by providing immersive, interactive environments with precise motion tracking. However, designing realistic VR-based motor…

Quantitative Methods · Quantitative Biology 2025-05-01 Cristina Rossi , Rini Varghese , Amy J Bastian

During VR demos we have performed over last few years, many participants (in the absence of any haptic feedback) have commented on their perceived ability to 'feel' differences between simulated molecular objects. The mechanisms for such…

Human-Computer Interaction · Computer Science 2020-05-08 Rhoslyn Roebuck Williams , Xan Varcoe , Becca R. Glowacki , Ella M. Gale , Alexander Jamieson-Binnie , David R. Glowacki

We introduce VR-Doh, an open-source, hands-on 3D modeling system that enables intuitive creation and manipulation of elastoplastic objects in Virtual Reality (VR). By customizing the Material Point Method (MPM) for real-time simulation of…

Graphics · Computer Science 2025-06-25 Zhaofeng Luo , Zhitong Cui , Shijian Luo , Mengyu Chu , Minchen Li

Drug development is a wide scientific field that faces many challenges these days. Among them are extremely high development costs, long development times, as well as a low number of new drugs that are approved each year. To solve these…

Biomolecules · Quantitative Biology 2022-11-08 Christoph Gorgulla

Virtual Reality (VR) and Augmented Reality (AR) tools have been applied in all engineering fields in order to avoid the use of physical prototypes, to train in high-risk situations, and to interpret real or simulated results. In order to…

Human-Computer Interaction · Computer Science 2025-01-17 Shahin Doroudian

Mixed Reality (MR) technologies such as Virtual and Augmented Reality (VR, AR) are well established in medical practice, enhancing diagnostics, treatment, and education. However, there are still some limitations and challenges that may be…

Human-Computer Interaction · Computer Science 2025-07-28 Aliaksandr Marozau , Barbara Karpowicz , Tomasz Kowalewski , Pavlo Zinevych , Wiktor Stawski , Adam Kuzdraliński , Wiesław Kopeć

Molecular dynamics (MD) simulations and computer-aided drug design (CADD) have advanced substantially over the past two decades, thanks to continuous computer hardware and software improvements. Given these advancements, MD simulations are…

Quantitative Methods · Quantitative Biology 2023-11-29 Mayar Ahmed , Alex M. Maldonado , Jacob D. Durrant

This paper presents a molecular mechanics study using a molecular dynamics software (NAMD) coupled to virtual reality (VR) techniques for intuitive Bio-NanoRobotic prototyping. Using simulated Bio-Nano environments in VR, the operator can…

Biological Physics · Physics 2007-08-15 Mustapha Hamdi , Gaurav Sharma , A. Ferreira , Constantinos Mavroidis

Molecular visualization software has long supported research and education in chemical and structural sciences, but consumer devices constrained to 2D inputs and outputs pose two major challenges: they poorly convey 3D nature, and 3D…

Chemical Physics · Physics 2025-09-05 Luciano A. Abriata

Modern medicine demands innovations in medical education, particularly in the learning of human anatomy, traditionally taught through textbooks, dissections, and lectures. Virtual Reality (VR) has emerged as a promising tool to address the…

Human-Computer Interaction · Computer Science 2024-11-11 Myint Zu Than , Kian Meng Yap

Virtual Reality (VR) has shown great potential to revolutionize the market by providing users immersive experiences with freedom of movement. Compared to traditional video streaming, VR is with ultra high-definition and dynamically changes…

Networking and Internet Architecture · Computer Science 2021-03-12 Miao Hu , Xianzhuo Luo , Jiawen Chen , Young Choon Lee , Yipeng Zhou , Di Wu

Virtual reality (VR) is not a new technology but has been in development for decades, driven by advances in computer technology. Currently, VR technology is increasingly being used in applications to enable immersive, yet controlled…

Human-Computer Interaction · Computer Science 2022-11-24 Hong Gao
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