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Purpose: Aortic dissections are life-threatening cardiovascular conditions requiring accurate segmentation of true lumen (TL), false lumen (FL), and false lumen thrombosis (FLT) from CTA images for effective management. Manual segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Hao Xu , Ruth Lim , Brian E. Chapman

Segmentation of the coronary artery is an important task for the quantitative analysis of coronary computed tomography angiography (CCTA) images and is being stimulated by the field of deep learning. However, the complex structures with…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Xiaoyu Yang , Lijian Xu , Simon Yu , Qing Xia , Hongsheng Li , Shaoting Zhang

Despite coronary artery calcium scoring being considered a largely solved problem within the realm of medical artificial intelligence, this paper argues that significant improvements can still be made. By shifting the focus from pathology…

Segmentation of the heart in cardiac cine MR is clinically used to quantify cardiac function. We propose a fully automatic method for segmentation and disease classification using cardiac cine MR images. A convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2017-08-04 Jelmer M. Wolterink , Tim Leiner , Max A. Viergever , Ivana Isgum

Cardiac function is of paramount importance for both prognosis and treatment of different pathologies such as mitral regurgitation, ischemia, dyssynchrony and myocarditis. Cardiac behavior is determined by structural and functional…

Computer Vision and Pattern Recognition · Computer Science 2017-08-25 Ariel H. Curiale , Flavio D. Colavecchia , Pablo Kaluza , Roberto A. Isoardi , German Mato

Background and Objective: Incomplete Kawasaki disease (KD) has often been misdiagnosed due to a lack of the clinical manifestations of classic KD. However, it is associated with a markedly higher prevalence of coronary artery lesions.…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Haeyun Lee , Yongsoon Eun , Jae Youn Hwang , Lucy Youngmin Eun

Cardiovascular disease (CD) is the number one leading cause of death worldwide, accounting for more than 17 million deaths in 2015. Critical indicators of CD include heart murmurs, intense sounds emitted by the heart during periods of…

Signal Processing · Electrical Eng. & Systems 2021-01-01 Ankit Gupta , George Tang , Sylesh Suresh

During the diagnosis of ischemic strokes, the Circle of Willis and its surrounding vessels are the arteries of interest. Their visualization in case of an acute stroke is often enabled by Computed Tomography Angiography (CTA). Still, the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Florian Thamm , Markus Jürgens , Oliver Taubmann , Aleksandra Thamm , Leonhard Rist , Hendrik Ditt , Andreas Maier

Myocardial characterization is essential for patients with myocardial infarction and other myocardial diseases, and the assessment is often performed using cardiac magnetic resonance (CMR) sequences. In this study, we propose a fully…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Xiaoran Zhang , Michelle Noga , Kumaradevan Punithakumar

Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Carlo Biffi , Ozan Oktay , Giacomo Tarroni , Wenjia Bai , Antonio De Marvao , Georgia Doumou , Martin Rajchl , Reem Bedair , Sanjay Prasad , Stuart Cook , Declan O'Regan , Daniel Rueckert

Automatic lesion segmentation on thoracic CT enables rapid quantitative analysis of lung involvement in COVID-19 infections. However, obtaining a large amount of voxel-level annotations for training segmentation networks is prohibitively…

Image and Video Processing · Electrical Eng. & Systems 2021-11-22 Weiyi Xie , Colin Jacobs , Jean-Paul Charbonnier , Bram van Ginneken

Most deep learning models in medical imaging are trained on adult data with unclear performance on pediatric images. In this work, we aim to address this challenge in the context of automated anatomy segmentation in whole-body Computed…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Chih-Ying Liu , Jeya Maria Jose Valanarasu , Camila Gonzalez , Curtis Langlotz , Andrew Ng , Sergios Gatidis

Coronary artery disease, the leading cause of cardiovascular mortality worldwide, can be assessed non-invasively by coronary computed tomography angiography (CCTA). Despite progress in automated CCTA analysis using deep learning, clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Jinkui Hao , Gorkem Durak , Halil Ertugrul Aktas , Ulas Bagci , Bradley D. Allen , Nilay S. Shah , Bo Zhou

Quantifying uncertainty of predictions has been identified as one way to develop more trustworthy artificial intelligence (AI) models beyond conventional reporting of performance metrics. When considering their role in a clinical decision…

Non-contrast computed tomography calcium scoring (CTCS) is a cost-effective imaging modality widely used to detect coronary artery calcifications. This study aimed to develop an advanced machine learning framework that utilizes quantitative…

Deep neural network architectures have traditionally been designed and explored with human expertise in a long-lasting trial-and-error process. This process requires huge amount of time, expertise, and resources. To address this tedious…

Machine Learning · Statistics 2018-07-23 Aliasghar Mortazi , Ulas Bagci

Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Xueshen Li , Hongshan Liu , Xiaoyu Song , Brigitta C. Brott , Silvio H. Litovsky , Yu Gan

Coronary Computed Tomography Angiography (CCTA) evaluation of chest-pain patients in an Emergency Department (ED) is considered appropriate. While a negative CCTA interpretation supports direct patient discharge from an ED, labor-intensive…

In patients with coronary artery stenoses of intermediate severity, the functional significance needs to be determined. Fractional flow reserve (FFR) measurement, performed during invasive coronary angiography (ICA), is most often used in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Majd Zreik , Nikolas Lessmann , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…