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Automatic segmentation of neuronal topology is critical for handling large scale neuroimaging data, as it can greatly accelerate neuron annotation and analysis. However, the intricate morphology of neuronal branches and the occlusions among…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Huayu Fu , Jiamin Li , Haozhi Qu , Xiaolin Hu , Zengcai Guo

Accurate lung lesion segmentation from Computed Tomography (CT) images is crucial to the analysis and diagnosis of lung diseases such as COVID-19 and lung cancer. However, the smallness and variety of lung nodules and the lack of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Changwei Wang , Rongtao Xu , Shibiao Xu , Weiliang Meng , Jun Xiao , Xiaopeng Zhang

Deep learning, as a promising new area of machine learning, has attracted a rapidly increasing attention in the field of medical imaging. Compared to the conventional machine learning methods, deep learning requires no hand-tuned feature…

Quantitative Methods · Quantitative Biology 2016-11-29 He Yang , Hengyong Yu , Ge Wang

Early detection of lung cancer in chest radiographs (CXRs) is crucial for improving patient outcomes, yet nodule detection remains challenging due to their subtle appearance and variability in radiological characteristics like size,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Aryan Goyal , Shreshtha Singh , Ashish Mittal , Manoj Tadepalli , Piyush Kumar , Preetham Putha

A computer-aided detection (CAD) system for the identification of lung internal nodules in low-dose multi-detector helical Computed Tomography (CT) images was developed in the framework of the MAGIC-5 project. The three modules of our lung…

Purpose: The lung nodules localization in CT scan images is the most difficult task due to the complexity of the arbitrariness of shape, size, and texture of lung nodules. This is a challenge to be faced when coming to developing different…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Haytham Al Ewaidat , Youness El Brag

Deep learning has revolutionized medical and biological imaging, particularly in segmentation tasks. However, segmenting biological cells remains challenging due to the high variability and complexity of cell shapes. Addressing this…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Tianhao Zhang , Heather J. McCourty , Berardo M. Sanchez-Tafolla , Anton Nikolaev , Lyudmila S. Mihaylova

Recently, Computer-Aided Diagnosis (CAD) systems have emerged as indispensable tools in clinical diagnostic workflows, significantly alleviating the burden on radiologists. Nevertheless, despite their integration into clinical settings, CAD…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Muwei Jian , Hongyu Chen , Zaiyong Zhang , Nan Yang , Haorang Zhang , Lifu Ma , Wenjing Xu , Huixiang Zhi

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Automatic diagnosing lung cancer from Computed Tomography (CT) scans involves two steps: detect all suspicious lesions (pulmonary nodules) and evaluate the whole-lung/pulmonary malignancy. Currently, there are many studies about the first…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Fangzhou Liao , Ming Liang , Zhe Li , Xiaolin Hu , Sen Song

Objective: Lung cancer is a leading cause of cancer-related mortality worldwide, primarily due to delayed diagnosis and poor early detection. This study aims to develop a computer-aided diagnosis (CAD) system that leverages large…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Hafza Eman , Furqan Shaukat , Muhammad Hamza Zafar , Syed Muhammad Anwar

This paper proposes a novel and efficient method to build a Computer-Aided Diagnoses (CAD) system for lung nodule detection based on Computed Tomography (CT). This task was treated as an Object Detection on Video (VID) problem by imitating…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Ning Li , Haopeng Liu , Bin Qiu , Wei Guo , Shijun Zhao , Kungang Li , Jie He

Objective: In clinical practice, small lung nodules can be easily overlooked by radiologists. The paper aims to provide an efficient and accurate detection system for small lung nodules while keeping good performance for large nodules.…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Sunyi Zheng , Ludo J. Cornelissen , Xiaonan Cui , Xueping Jing , Raymond N. J. Veldhuis , Matthijs Oudkerk , Peter M. A. van Ooijen

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector helical Computed Tomography (CT) images with 1.25 mm slice thickness is presented. The basic modules of our lung-CAD system, a…

Medical images from different healthcare centers exhibit varied data distributions, posing significant challenges for adapting lung nodule detection due to the domain shift between training and application phases. Traditional unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2024-08-05 Haifeng Zhao , Lixiang Jiang , Leilei Ma , Dengdi Sun , Yanping Fu

Early detection of lung nodules is of great importance in lung cancer screening. Existing research recognizes the critical role played by CAD systems in early detection and diagnosis of lung nodules. However, many CAD systems, which are…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Naji Khosravan , Ulas Bagci

Image segmentation is a fundamental problem in medical image analysis. In recent years, deep neural networks achieve impressive performances on many medical image segmentation tasks by supervised learning on large manually annotated data.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-26 Ling Zhang , Vissagan Gopalakrishnan , Le Lu , Ronald M. Summers , Joel Moss , Jianhua Yao

PURPOSE: This study aimed to develop a deep learning-based tool to detect and localize lung nodules with chest radiographs(CXRs). We expected it to enhance the efficiency of interpreting CXRs and reduce the possibilities of delayed…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Yang Tai , Yu-Wen Fang , Fang-Yi Su , Jung-Hsien Chiang

Lung cancer follow-up is a complex, error prone, and time consuming task for clinical radiologists. Several lung CT scan images taken at different time points of a given patient need to be individually inspected, looking for possible…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel Ángel González Ballester

Lung cancer has been one of the major threats to human life for decades. Computer-aided diagnosis can help with early lung nodul detection and facilitate subsequent nodule characterization. Large Visual Language models (VLMs) have been…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Furqan Shaukat , Syed Muhammad Anwar , Abhijeet Parida , Van Khanh Lam , Marius George Linguraru , Mubarak Shah