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Motivated by chemical reaction rules, we introduce a rule-based epidemiological framework for the systematic mathematical modelling of future pandemics. Here we stress that we do not have a specific model in mind, but a whole collection of…

Populations and Evolution · Quantitative Biology 2024-05-24 David Alonso , Steffen Bauer , Markus Kirkilionis , Lisa Maria Kreusser , Luca Sbano

Understanding the spread of SARS-CoV-2 has been one of the most pressing problems of the recent past. Network models present a potent approach to studying such spreading phenomena because of their ability to represent complex social…

Social and Information Networks · Computer Science 2023-11-01 Christine Hedde-von Westernhagen , Javier Garcia-Bernardo , Ayoub Bagheri

We propose a forecasting method for predicting epidemiological health series on a two-week horizon at the regional and interregional resolution. The approach is based on model order reduction of parametric compartmental models, and is…

Methodology · Statistics 2020-12-11 Athmane Bakhta , Thomas Boiveau , Yvon Maday , Olga Mula

Modern Bayesian approaches and workflows emphasize in how simulation is important in the context of model developing. Simulation can help researchers understand how the model behaves in a controlled setting and can be used to stress the…

A pandemic poses particular challenges to decision-making because of the need to continuously adapt decisions to rapidly changing evidence and available data. For example, which countermeasures are appropriate at a particular stage of the…

The COVID-19 pandemic represents the most significant public health disaster since the 1918 influenza pandemic. During pandemics such as COVID-19, timely and reliable spatio-temporal forecasting of epidemic dynamics is crucial. Deep…

Machine Learning · Computer Science 2020-11-25 Lijing Wang , Aniruddha Adiga , Srinivasan Venkatramanan , Jiangzhuo Chen , Bryan Lewis , Madhav Marathe

Epidemic models are always simplifications of real world epidemics. Which real world features to include, and which simplifications to make, depend both on the disease of interest and on the purpose of the modelling. In the present paper we…

Probability · Mathematics 2008-12-19 Tom Britton , David Lindenstrand

The COVID-19 pandemic response relied heavily on statistical and machine learning models to predict key outcomes such as case prevalence and fatality rates. These predictions were instrumental in enabling timely public health interventions…

The current pandemic has highlighted the need for methodologies that can quickly and reliably prioritize clinically approved compounds for their potential effectiveness for SARS-CoV-2 infections. In the past decade, network medicine has…

This paper addresses statistical modelling and forecasting of key indicators describing the severity of a developing pandemic, using routinely reported daily counts of infections, hospitalizations, deaths (both in and out of hospital), and…

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

SARS-CoV-2 lineages are defined according to placement in a phylogenetic tree, but approximated by a list of mutations based on sequences collected from clinical sampling. Wastewater lineage abundance is generally found under the assumption…

Methodology · Statistics 2025-08-06 Devan Becker

The COVID-19 pandemic has been a great catastrophe that upended human lives and caused millions of deaths all over the world. The rapid spread of the virus, with its early-stage exponential growth and subsequent 'waves', caught many medical…

Populations and Evolution · Quantitative Biology 2022-05-31 Anne V. Ginzburg , Valeriy V. Ginzburg , Julia O. Ginzburg , Ana Garcia Arias , Leela Rakesh

The lack of epidemiological data in wireless sensor networks (WSNs) is a fundamental difficulty in constructing robust models to forecast and mitigate threats such as viruses and worms. Many studies have examined different epidemic models…

Machine Learning · Computer Science 2025-11-21 Chukwunonso Henry Nwokoye , Blessing Oluchi , Sharna Waldron , Peace Ezzeh

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

Methodology · Statistics 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian

In wireless sensor networks (WSNs), main task of each sensor node is to sense the physical activity (i.e., targets or disaster conditions) and then to report it to the control center for further process. For this, sensor nodes are attached…

Networking and Internet Architecture · Computer Science 2018-01-16 Rajeev K. Shakya

COVID-19 pandemic has reshaped our world in a timescale much shorter than what we can understand. Particularities of SARS-CoV-2, such as its persistence in surfaces and the lack of a curative treatment or vaccine against COVID-19, have…

The outbreak of the SARS-CoV-2 pandemic of the new COVID-19 disease (COVID-19 for short) demands empowering existing medical, economic, and social emergency backend systems with data analytics capabilities. An impediment in taking…

Software Engineering · Computer Science 2021-10-14 Aakash Ahmad , Madhushi Bandara , Mahdi Fahmideh , Henderik A. Proper , Giancarlo Guizzardi , Jeffrey Soar

The outburst of COVID-19 in late 2019 was the start of a health crisis that shook the world and took millions of lives in the ensuing years. Many governments and health officials failed to arrest the rapid circulation of infection in their…

Machine Learning · Computer Science 2022-12-20 Mehrdad Fazli , Heman Shakeri

Concentrations of pathogen genomes measured in wastewater have recently become available as a new data source to use when modeling the spread of infectious diseases. One promising use for this data source is inference of the effective…

Methodology · Statistics 2024-06-24 Isaac H. Goldstein , Daniel M. Parker , Sunny Jiang , Volodymyr M. Minin