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Artificial Intelligence (AI) and Machine-Learning (ML) models have been increasingly used in medical products, such as medical device software. General considerations on the statistical aspects for the evaluation of AI/ML-enabled medical…

Methodology · Statistics 2023-03-10 Feiming Chen , Hong Laura Lu , Arianna Simonetti

A trained ML model is deployed on another `test' dataset where target feature values (labels) are unknown. Drift is distribution change between the training and deployment data, which is concerning if model performance changes. For a…

Applications · Statistics 2022-09-07 Samuel Ackerman , Eitan Farchi , Orna Raz , Marcel Zalmanovici , Parijat Dube

Driver distraction has become a significant cause of severe traffic accidents over the past decade. Despite the growing development of vision-driven driver monitoring systems, the lack of comprehensive perception datasets restricts road…

Computer Vision and Pattern Recognition · Computer Science 2023-08-02 Dingkang Yang , Shuai Huang , Zhi Xu , Zhenpeng Li , Shunli Wang , Mingcheng Li , Yuzheng Wang , Yang Liu , Kun Yang , Zhaoyu Chen , Yan Wang , Jing Liu , Peixuan Zhang , Peng Zhai , Lihua Zhang

Purpose High dimensional, multimodal data can nowadays be analyzed by huge deep neural networks with little effort. Several fusion methods for bringing together different modalities have been developed. Given the prevalence of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Christian Gapp , Elias Tappeiner , Martin Welk , Karl Fritscher , Elke Ruth Gizewski , Rainer Schubert

Artificial intelligence (AI) in healthcare has led to many promising developments; however, increasingly, AI research is funded by the private sector leading to potential trade-offs between benefits to patients and benefits to industry.…

Computers and Society · Computer Science 2026-01-13 Rina Khan , Annabelle Sauve , Imaan Bayoumi , Amber L. Simpson , Catherine Stinson

Recent artificial intelligence (AI) technologies show remarkable evolution in various academic fields and industries. However, in the real world, dynamic data lead to principal challenges for deploying AI models. An unexpected data change…

Machine Learning · Computer Science 2024-02-21 Jeng-Lin Li , Chih-Fan Hsu , Ming-Ching Chang , Wei-Chao Chen

Deep learning has the potential to automate many clinically useful tasks in medical imaging. However translation of deep learning into clinical practice has been hindered by issues such as lack of the transparency and interpretability in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-04 Charles Lu , Andreanne Lemay , Ken Chang , Katharina Hoebel , Jayashree Kalpathy-Cramer

While deep learning models become more widespread, their ability to handle unseen data and generalize for any scenario is yet to be challenged. In medical imaging, there is a high heterogeneity of distributions among images based on the…

Image and Video Processing · Electrical Eng. & Systems 2025-05-01 Eduardo H. P. Pooch , Pedro L. Ballester , Rodrigo C. Barros

BACKGROUND AND OBJECTIVES: The multiple chest x-ray datasets released in the last years have ground-truth labels intended for different computer vision tasks, suggesting that performance in automated chest-xray interpretation might improve…

Clinical diagnosis is a complex cognitive process, grounded in dynamic cue acquisition and continuous expertise accumulation. Yet most current artificial intelligence (AI) systems are misaligned with this reality, treating diagnosis as…

Artificial Intelligence · Computer Science 2026-03-12 Ruiyang Ren , Yuhao Wang , Yunsen Liang , Lan Luo , Jing Liu , Haifeng Wang , Cong Feng , Yinan Zhang , Chunyan Miao , Ji-Rong Wen , Wayne Xin Zhao

AI models are increasingly deployed in live clinical environments where they must perform reliably across complex, high-stakes workflows that standard training and validation datasets were never designed to capture. Evaluating these systems…

Artificial Intelligence · Computer Science 2026-05-12 Prasanna Desikan , Harshit Rajgarhia , Shivali Dalmia , Ananya Mantravadi

This paper reviews the challenges hindering the widespread adoption of artificial intelligence (AI) solutions in the healthcare industry, focusing on computer vision applications for medical imaging, and how interoperability and…

The current generation of deep neural networks has achieved close-to-human results on "closed-set" image recognition; that is, the classes being evaluated overlap with the training classes. Many recent methods attempt to address the…

Image and Video Processing · Electrical Eng. & Systems 2021-10-22 Zongyuan Ge , Xin Wang

Performance uncertainty quantification is essential for reliable validation and eventual clinical translation of medical imaging artificial intelligence (AI). Confidence intervals (CIs) play a central role in this process by indicating how…

The translation of artificial intelligence (AI) systems into clinical practice requires bridging fundamental gaps between explainable AI theory, clinician expectations, and governance requirements. While conceptual frameworks define what…

Computers and Society · Computer Science 2025-11-05 Alexander Bakumenko , Aaron J. Masino , Janine Hoelscher

Chest X-ray interpretation is one of the most frequently performed diagnostic tasks in medicine and a primary target for AI development, yet current vision-language models are primarily trained on datasets of paired images and reports, not…

In the contemporary digital landscape, the continuous generation of extensive streaming data across diverse domains has become pervasive. Yet, a significant portion of this data remains unlabeled, posing a challenge in identifying…

Computational Engineering, Finance, and Science · Computer Science 2025-08-25 Jin Li , Kleanthis Malialis , Christos G. Panayiotou , Marios M. Polycarpou

Although there have been several recent advances in the application of deep learning algorithms to chest x-ray interpretation, we identify three major challenges for the translation of chest x-ray algorithms to the clinical setting. We…

Image and Video Processing · Electrical Eng. & Systems 2020-03-12 Pranav Rajpurkar , Anirudh Joshi , Anuj Pareek , Phil Chen , Amirhossein Kiani , Jeremy Irvin , Andrew Y. Ng , Matthew P. Lungren

Artificial Intelligence (AI) holds great promise for transforming healthcare, particularly in disease diagnosis, prognosis, and patient care. The increasing availability of digital medical data, such as images, omics, biosignals, and…

Artificial Intelligence · Computer Science 2025-10-17 Pedro A. Moreno-Sánchez , Javier Del Ser , Mark van Gils , Jussi Hernesniemi

In the trajectory planning of automated driving, data-driven statistical artificial intelligence (AI) methods are increasingly established for predicting the emergent behavior of other road users. While these methods achieve exceptional…

Robotics · Computer Science 2025-04-28 Lars Ullrich , Zurab Mujirishvili , Knut Graichen