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Purpose: Respiratory motion and the interplay effect cause the dose delivered to a patient with spot-scanned proton therapy to differ from the dose planned for during optimization. A new 4D robust optimization methodology was developed…

In-situ measurements of space plasma throughout the solar system require high time resolution to understand the plasma's kinetic fine structure and evolution. In this context, research~is conducted to design instruments with the capability…

Instrumentation and Detectors · Physics 2020-12-01 Benjamin Criton , Georgios Nicolaou , Daniel Verscharen

We have determined the depth-dose curve, the penetration range, and the water equivalent ratio (WER), for proton beams of clinical energies in cortical bone, by means of a detailed and accurate simulation that combines molecular dynamics…

Medical Physics · Physics 2024-09-18 Ana María Zamora-Vinaroz , Pablo de Vera , Isabel Abril , Rafael Garcia-Molina

Computer vision performances have been significantly improved in recent years by Convolutional Neural Networks(CNN). Currently, applications using CNN algorithms are deployed mainly on general purpose hardwares, such as CPUs, GPUs or FPGAs.…

Computer Vision and Pattern Recognition · Computer Science 2018-05-04 Baohua Sun , Lin Yang , Patrick Dong , Wenhan Zhang , Jason Dong , Charles Young

Travel time tomography for the velocity structure of a medium is a highly non-linear and non-unique inverse problem. Monte Carlo methods are becoming increasingly common choices to provide probabilistic solutions to tomographic problems but…

Computational Physics · Physics 2020-05-08 Stephanie Earp , Andrew Curtis

Deep learning (DL) has successfully automated dose distribution prediction in radiotherapy planning, enhancing both efficiency and quality. However, existing methods suffer from the over-smoothing problem for their commonly used L1 or L2…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Zhenghao Feng , Lu Wen , Jianghong Xiao , Yuanyuan Xu , Xi Wu , Jiliu Zhou , Xingchen Peng , Yan Wang

Accurate prediction of Drug-Target Affinity (DTA) is of vital importance in early-stage drug discovery, facilitating the identification of drugs that can effectively interact with specific targets and regulate their activities. While wet…

Biomolecules · Quantitative Biology 2023-10-18 Qizhi Pei , Lijun Wu , Jinhua Zhu , Yingce Xia , Shufang Xie , Tao Qin , Haiguang Liu , Tie-Yan Liu , Rui Yan

A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed. The GDS algorithm is intrinsically faster than…

Medical Physics · Physics 2011-11-10 Nobuyuki Kanematsu , Shunsuke Yonai , Azusa Ishizaki

Variations in Magnetic resonance imaging (MRI) scanners and acquisition protocols cause distribution shifts that degrade reconstruction performance on unseen data. Test-time adaptation (TTA) offers a promising solution to address this…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Lipei Zhang , Rui Sun , Zhongying Deng , Yanqi Cheng , Carola-Bibiane Schönlieb , Angelica I Aviles-Rivero

Early diagnosis of dementia, particularly in the prodromal stage (i.e., mild cognitive impairment, or MCI), has become a research and clinical priority but remains challenging. Automated analysis of the drawing process has been studied as a…

Signal Processing · Electrical Eng. & Systems 2022-11-17 Yasunori Yamada , Masatomo Kobayashi , Kaoru Shinkawa , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

Diffusion Transformers have become a dominant paradigm in visual generation, yet their low inference efficiency remains a key bottleneck hindering further advancement. Among common training-free techniques, caching offers high acceleration…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Tong Shao , Yusen Fu , Guoying Sun , Jingde Kong , Zhuotao Tian , Jingyong Su

Distribution shift widely exists in medical images acquired from different medical centres and poses a significant obstacle to deploying the pre-trained semantic segmentation model in real-world applications. Test-time adaptation has proven…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Ziyang Chen , Yongsheng Pan , Yiwen Ye , Mengkang Lu , Yong Xia

In this study, cone-beam single projection and axial CT scans are modeled with a software package - DOCTORS, which solves the linear Boltzmann equation using the discrete ordinates method. Phantoms include a uniform 35 cm diameter water…

Medical Physics · Physics 2018-11-30 Edward T. Norris , Xin Liu

Dual-energy computed tomography (DECT) is a promising technology that has shown a number of clinical advantages over conventional X-ray CT, such as improved material identification, artifact suppression, etc. For proton therapy treatment…

With the introduction of shared spectrum sensing and beam-forming based multi-antenna transceivers, 5G networks demand spectrum sensing to identify opportunities in time, frequency, and spatial domains. Narrow beam-forming makes it…

Signal Processing · Electrical Eng. & Systems 2021-07-26 Piyush Sahoo , Romesh Rajoria , Shivam Chandhok , S. J. Darak , Danilo Pau , Hem-Dutt Dabral

We propose an experimental scheme for performing sensitive, high-precision laser spectroscopy studies on fast exotic isotopes. By inducing a step-wise resonant ionization of the atoms travelling inside an electric field and subsequently…

Nuclear Experiment · Physics 2024-03-04 Silviu-Marian Udrescu , Diego Alejandro Torres , Ronald Fernando Garcia Ruiz

The mechanism driving core-collapse supernovae is sensitive to the interplay between matter and neutrino radiation. However, neutrino radiation transport is very difficult to simulate, and several radiation transport methods of varying…

High Energy Astrophysical Phenomena · Physics 2017-10-11 Sherwood Richers , Hiroki Nagakura , Christian D. Ott , Joshua Dolence , Kohsuke Sumiyoshi , Shoichi Yamada

Surgical scene understanding and multi-tasking learning are crucial for image-guided robotic surgery. Training a real-time robotic system for the detection and segmentation of high-resolution images provides a challenging problem with the…

Computer Vision and Pattern Recognition · Computer Science 2020-10-19 Mobarakol Islam , Vibashan VS , Hongliang Ren

To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…

Model-assisted designs have garnered significant attention in recent years due to their high accuracy in identifying the maximum tolerated dose (MTD) and their operational simplicity. To identify the MTD, they employ estimated dose limiting…

Applications · Statistics 2025-08-19 Rentaro Wakayama , Tomotaka Momozaki , Shuji Ando
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