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Quantum machine learning researchers often rely on incorporating Tensor Networks (TN) into Deep Neural Networks (DNN) and variational optimization. However, the standard optimization techniques used for training the contracted trainable…

Quantum Physics · Physics 2023-10-04 Debanjan Konar , Dheeraj Peddireddy , Vaneet Aggarwal , Bijaya K. Panigrahi

Machine learning advances chemistry and materials science by enabling large-scale exploration of chemical space based on quantum chemical calculations. While these models supply fast and accurate predictions of atomistic chemical…

Chemical Physics · Physics 2019-06-25 K. T. Schütt , M. Gastegger , A. Tkatchenko , K. -R. Müller , R. J. Maurer

Data encoding remains a fundamental bottleneck in quantum machine learning, where amplitude encoding of high-dimensional classical vectors into quantum states incurs exponential cost. In this work, we propose a pre-trained tensor-train (TT)…

Quantum Physics · Physics 2026-02-11 Jun Qi , Chao-Han Huck Yang , Pin-Yu Chen , Min-Hsiu Hsieh

Machine learning potential (MLP) has been a popular topic in recent years for its potential to replace expensive first-principles calculations in some large systems. Meanwhile, message passing networks have gained significant attention due…

Computational Physics · Physics 2024-09-04 Junjie Wang , Yong Wang , Haoting Zhang , Ziyang Yang , Zhixin Liang , Jiuyang Shi , Hui-Tian Wang , Dingyu Xing , Jian Sun

Toxicity is a roadblock that prevents an inordinate number of drugs from being used in potentially life-saving applications. Deep learning provides a promising solution to finding ideal drug candidates; however, the vastness of chemical…

Quantum Physics · Physics 2024-05-13 Anthony M. Smaldone , Victor S. Batista

Accurately predicting enzyme functionality remains one of the major challenges in computational biology, particularly for enzymes with limited structural annotations or sequence homology. We present a novel multimodal Quantum Machine…

Machine Learning · Computer Science 2025-08-21 Murat Isik , Mandeep Kaur Saggi , Humaira Gowher , Sabre Kais

Deep learning has improved automated electrocardiogram (ECG) classification, but limited insight into prediction reliability hinders its use in safety-critical settings. This paper proposes UCTECG-Net, an uncertainty-aware hybrid…

Machine Learning · Computer Science 2026-02-19 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

Hybrid Quantum-Classical Machine Learning (ML) is an emerging field, amalgamating the strengths of both classical neural networks and quantum variational circuits on the current noisy intermediate-scale quantum devices. This paper performs…

The accurate prediction of biological features from genomic data is paramount for precision medicine and sustainable agriculture. For decades, neural network models have been widely popular in fields like computer vision, astrophysics and…

Genomics · Quantitative Biology 2022-03-15 Zhaoyi Zhang , Songyang Cheng , Claudia Solis-Lemus

Neural metrics for machine translation evaluation, such as COMET, exhibit significant improvements in their correlation with human judgments, as compared to traditional metrics based on lexical overlap, such as BLEU. Yet, neural metrics…

Computation and Language · Computer Science 2023-05-22 Ricardo Rei , Nuno M. Guerreiro , Marcos Treviso , Luisa Coheur , Alon Lavie , André F. T. Martins

Quantum Machine Learning (QML) offers tremendous potential but is currently limited by the availability of qubits. We introduce an innovative approach that utilizes pre-trained neural networks to enhance Variational Quantum Circuits (VQC).…

Machine Learning · Computer Science 2024-11-14 Jun Qi , Chao-Han Yang , Samuel Yen-Chi Chen , Pin-Yu Chen , Hector Zenil , Jesper Tegner

Learning from data has led to paradigm shifts in a multitude of disciplines, including web, text, and image search, speech recognition, as well as bioinformatics. Can machine learning enable similar breakthroughs in understanding quantum…

With the maturation of quantum computing technology, research has gradually shifted towards exploring its applications. Alongside the rise of artificial intelligence, various machine learning methods have been developed into quantum…

Quantum Physics · Physics 2025-03-14 Abel C. H. Chen

We present a technique for translating a black-box machine-learned classifier operating on a high-dimensional input space into a small set of human-interpretable observables that can be combined to make the same classification decisions. We…

High Energy Physics - Phenomenology · Physics 2021-04-21 Taylor Faucett , Jesse Thaler , Daniel Whiteson

Quantum computational chemistry holds great promise for simulating molecular systems more efficiently than classical methods by leveraging quantum bits to represent molecular wavefunctions. However, current implementations face significant…

Quantum Physics · Physics 2025-09-10 Weitang Li , Shi-Xin Zhang , Zirui Sheng , Cunxi Gong , Jianpeng Chen , Zhigang Shuai

Machine-learning force fields can deliver accurate molecular dynamics (MD) at high computational cost. For SO(3)-equivariant models such as MACE, there is little systematic evidence on whether reduced-precision arithmetic and GPU-optimized…

Machine Learning · Computer Science 2025-10-29 Alexandre Benoit

Representations are a foundational component of any modelling protocol, including on molecules and molecular solids. For tasks that depend on knowledge of both molecular conformation and 3D orientation, such as the modelling of molecular…

Machine Learning · Computer Science 2026-03-17 Michael Kilgour , Mark Tuckerman , Jutta Rogal

Rotation equivariance is a desirable property in many practical applications such as motion forecasting and 3D perception, where it can offer benefits like sample efficiency, better generalization, and robustness to input perturbations.…

Computer Vision and Pattern Recognition · Computer Science 2023-01-26 Serge Assaad , Carlton Downey , Rami Al-Rfou , Nigamaa Nayakanti , Ben Sapp

Despite their widespread success in various domains, Transformer networks have yet to perform well across datasets in the domain of 3D atomistic graphs such as molecules even when 3D-related inductive biases like translational invariance…

Machine Learning · Computer Science 2023-03-01 Yi-Lun Liao , Tess Smidt

Quantum neural networks (QNNs) and quantum kernels stand as prominent figures in the realm of quantum machine learning, poised to leverage the nascent capabilities of near-term quantum computers to surmount classical machine learning…

Quantum Physics · Physics 2023-12-14 Yiming Huang , Huiyuan Wang , Yuxuan Du , Xiao Yuan