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Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…
Retinal disease diagnosis is critical in preventing vision loss and reducing socioeconomic burdens. Globally, over 2.2 billion people are affected by some form of vision impairment, resulting in annual productivity losses estimated at $411…
In this project, we developed a deep learning system applied to human retina images for medical diagnostic decision support. The retina images were provided by EyePACS. These images were used in the framework of a Kaggle contest, whose…
Diabetic retinopathy (DR) is a leading cause of blindness worldwide, necessitating early detection to prevent vision loss. Current automated DR detection systems often struggle with poor-quality images, lack interpretability, and…
Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…
Automatic blood vessel segmentation from retinal images plays an important role in the diagnosis of many systemic and eye diseases, including retinopathy of prematurity. Current state-of-the-art research in blood vessel segmentation from…
Diabetic Retinopathy (DR) is a leading cause of preventable blindness among working-age adults worldwide, yet most automated screening systems are limited to image-level classification and lack clinically structured reporting. We propose…
Machine learning has demonstrated remarkable performance over finite datasets, yet whether the scores over the fixed benchmarks can sufficiently indicate the model's performance in the real world is still in discussion. In reality, an ideal…
Timely and affordable computer-aided diagnosis of retinal diseases is pivotal in precluding blindness. Accurate retinal vessel segmentation plays an important role in disease progression and diagnosis of such vision-threatening diseases. To…
In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…
Understanding why neural networks make certain decisions is pivotal for their use in safety-critical applications. Feature-Guided Analysis (FGA) extracts slices of neural networks relevant to their tasks. Existing feature-guided approaches…
Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…
Retinal foundation models aim to learn generalizable representations from diverse retinal images, facilitating label-efficient model adaptation across various ophthalmic tasks. Despite their success, current retinal foundation models are…
Retinal vessel segmentation is critical for the early diagnosis of vision-threatening and systemic diseases, especially in real-world clinical settings with limited computational resources. Although significant improvements have been made…
Diseases such as diabetic retinopathy and age-related macular degeneration pose a significant risk to vision, highlighting the importance of precise segmentation of retinal vessels for the tracking and diagnosis of progression. However,…
Worldwide, sight loss is commonly occurred by retinal diseases, with age-related macular degeneration (AMD) being a notable facet that affects elderly patients. Approaching 170 million persons wide-ranging have been spotted with AMD, a…
Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…
Predicting disease progression from longitudinal imaging is useful for clinical decision making and trial design. Recent methods have moved toward increasing generative complexity, but the conditions under which this complexity is necessary…
The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…
This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…