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Biomedical text mining is becoming increasingly important as the number of biomedical documents rapidly grows. With the progress in natural language processing (NLP), extracting valuable information from biomedical literature has gained…

Computation and Language · Computer Science 2019-10-21 Jinhyuk Lee , Wonjin Yoon , Sungdong Kim , Donghyeon Kim , Sunkyu Kim , Chan Ho So , Jaewoo Kang

Over the past few decades, Artificial Intelligence(AI) has progressed from the initial machine learning stage to the deep learning stage, and now to the stage of foundational models. Foundational models have the characteristics of…

Computation and Language · Computer Science 2024-11-28 Lewen Yang , Xuanyu Zhou , Juao Fan , Xinyi Xie , Shengxin Zhu

The emergence of deep learning has significantly enhanced the analysis of electrocardiograms (ECGs), a non-invasive method that is essential for assessing heart health. Despite the complexity of ECG interpretation, advanced deep learning…

Machine Learning · Computer Science 2023-06-05 Zibin Zhao

We study the problem of incorporating prior knowledge into a deep Transformer-based model,i.e.,Bidirectional Encoder Representations from Transformers (BERT), to enhance its performance on semantic textual matching tasks. By probing and…

Computation and Language · Computer Science 2021-02-23 Tingyu Xia , Yue Wang , Yuan Tian , Yi Chang

Transformer-based models have delivered impressive results on many tasks, particularly vision and language tasks. In many model training situations, conventional configurations are typically adopted. For example, we often set the base model…

Machine Learning · Computer Science 2023-05-19 Fuzhao Xue , Jianghai Chen , Aixin Sun , Xiaozhe Ren , Zangwei Zheng , Xiaoxin He , Yongming Chen , Xin Jiang , Yang You

Life and physical sciences have always been quick to adopt the latest advances in machine learning to accelerate scientific discovery. Examples of this are cell segmentation or cancer detection. Nevertheless, these exceptional results are…

Machine Learning · Computer Science 2022-04-26 Juan Manuel Parrilla-Gutierrez

Gene expression datasets offer insights into gene regulation mechanisms, biochemical pathways, and cellular functions. Additionally, comparing gene expression profiles between disease and control patients can deepen the understanding of…

Machine Learning · Computer Science 2025-03-27 Rita T. Sousa , Heiko Paulheim

Food image segmentation is an important task that has ubiquitous applications, such as estimating the nutritional value of a plate of food. Although machine learning models have been used for segmentation in this domain, food images pose…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Grant Sinha , Krish Parmar , Hilda Azimi , Amy Tai , Yuhao Chen , Alexander Wong , Pengcheng Xi

Imaging sites around the world generate growing amounts of medical scan data with ever more versatile and affordable technology. Large-scale studies acquire MRI for tens of thousands of participants, together with metadata ranging from…

Machine Learning · Computer Science 2024-04-23 Taro Langner

While model architectures and training strategies have become more generic and flexible with respect to different data modalities over the past years, a persistent limitation lies in the assumption of fixed quantities and arrangements of…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Lisa Weijler , Florian Kowarsch , Michael Reiter , Pedro Hermosilla , Margarita Maurer-Granofszky , Michael Dworzak

Transformer, which can benefit from global (long-range) information modeling using self-attention mechanisms, has been successful in natural language processing and 2D image classification recently. However, both local and global features…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Wenxuan Wang , Chen Chen , Meng Ding , Jiangyun Li , Hong Yu , Sen Zha

Proteins are responsible for the most diverse set of functions in biology. The ability to extract information from protein sequences and to predict the effects of mutations is extremely valuable in many domains of biology and medicine.…

Quantitative Methods · Quantitative Biology 2018-01-04 Sam Sinai , Eric Kelsic , George M. Church , Martin A. Nowak

Modern single-cell flow and mass cytometry technologies measure the expression of several proteins of the individual cells within a blood or tissue sample. Each profiled biological sample is thus represented by a set of hundreds of…

Machine Learning · Computer Science 2022-06-29 Siyuan Shan , Vishal Baskaran , Haidong Yi , Jolene Ranek , Natalie Stanley , Junier Oliva

Gene enhancers control when and where genes switch on, yet their sequence diversity and tissue specificity make them hard to pinpoint in colorectal cancer. We take a sequence-only route and fine-tune DNABERT-2, a transformer genomic…

Genomics · Quantitative Biology 2025-10-01 Darren King , Yaser Atlasi , Gholamreza Rafiee

Encoding and decoding models are widely used in systems, cognitive, and computational neuroscience to make sense of brain-activity data. However, the interpretation of their results requires care. Decoding models can help reveal whether…

Neurons and Cognition · Quantitative Biology 2019-04-29 Nikolaus Kriegeskorte , Pamela K. Douglas

Obtaining effective representations of DNA sequences is crucial for genome analysis. Metagenomic binning, for instance, relies on genome representations to cluster complex mixtures of DNA fragments from biological samples with the aim of…

Machine Learning · Computer Science 2024-11-05 Abdulkadir Celikkanat , Andres R. Masegosa , Thomas D. Nielsen

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray…

Artificial Intelligence · Computer Science 2016-12-14 Rajendra Rana Bhat , Vivek Viswanath , Xiaolin Li

Multi-task learning (MTL) has achieved remarkable success in natural language processing applications. In this work, we study a multi-task learning model with multiple decoders on varieties of biomedical and clinical natural language…

Computation and Language · Computer Science 2020-05-07 Yifan Peng , Qingyu Chen , Zhiyong Lu

Genomics are rapidly transforming medical practice and basic biomedical research, providing insights into disease mechanisms and improving therapeutic strategies, particularly in cancer. The ability to predict the future course of a…

Neural and Evolutionary Computing · Computer Science 2016-09-29 Safoora Yousefi , Congzheng Song , Nelson Nauata , Lee Cooper

In the global challenge of understanding and characterizing biodiversity, short species-specific genomic sequences known as DNA barcodes play a critical role, enabling fine-grained comparisons among organisms within the same kingdom of…