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Despite high global prevalence of hepatic steatosis, no automated diagnostics demonstrated generalizability in detecting steatosis on multiple international datasets. Traditionally, hepatic steatosis detection relies on clinicians selecting…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Zhongyi Zhang , Guixia Li , Ziqiang Wang , Feng Xia , Ning Zhao , Huibin Nie , Zezhong Ye , Joshua Lin , Yiyi Hui , Xiangchun Liu

Background & Aims: Hepatic steatosis is a major cause of chronic liver disease. 2D ultrasound is the most widely used non-invasive tool for screening and monitoring, but associated diagnoses are highly subjective. We developed a scalable…

Image and Video Processing · Electrical Eng. & Systems 2021-10-13 Bowen Li , Dar-In Tai , Ke Yan , Yi-Cheng Chen , Shiu-Feng Huang , Tse-Hwa Hsu , Wan-Ting Yu , Jing Xiao , Le Lu , Adam P. Harrison

Liver steatosis is known as the abnormal accumulation of lipids within cells. An accurate quantification of steatosis area within the liver histopathological microscopy images plays an important role in liver disease diagnosis and…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Xiaoyuan Guo , Fusheng Wang , George Teodorou , Alton B. Farris , Jun Kong

An accurate steatosis quantification with pathology tissue samples is of high clinical importance. However, such pathology measurement is manually made in most clinical practices, subject to severe reader variability due to large sampling…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Mousumi Roy , Fusheng Wang , George Teodoro , Miriam B Vos , Alton Brad Farris , Jun Kong

It is critically important to detect the content of liver fat as it is related to cardiac complications and cardiovascular disease mortality. However, existing methods are either associated with high cost and/or medical complications (e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-03 Qiyue Wang , Wu Xue , Xiaoke Zhang , Fang Jin , James Hahn

We present an end-to-end deep learning framework for automated liver cirrhosis stage estimation from multi-sequence MRI. Cirrhosis is the severe scarring (fibrosis) of the liver and a common endpoint of various chronic liver diseases. Early…

Background: Recruitment for cohorts involving complex liver diseases, such as hepatocellular carcinoma and liver cirrhosis, often requires interpreting semantically complex criteria. Traditional manual screening methods are time-consuming…

Artificial Intelligence · Computer Science 2025-02-27 Xiongbin Gui , Hanlin Lv , Xiao Wang , Longting Lv , Yi Xiao , Lei Wang

In the realm of liver transplantation, accurately determining hepatic steatosis levels is crucial. Recognizing the essential need for improved diagnostic precision, particularly for optimizing diagnosis time by swiftly handling…

Background: Automated analysis of CT scans for abdominal organ measurement is crucial for improving diagnostic efficiency and reducing inter-observer variability. Manual segmentation and measurement of organs such as the kidneys, liver,…

Objectives: to propose a fully-automatic computer-aided diagnosis (CAD) solution for liver lesion characterization, with uncertainty estimation. Methods: we enrolled 400 patients who had either liver resection or a biopsy and was diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Peng Wang , Yuhsuan Wu , Bolin Lai , Xiao-Yun Zhou , Le Lu , Wendi Liu , Huabang Zhou , Lingyun Huang , Jing Xiao , Adam P. Harrison , Ningyang Jia , Heping Hu

Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…

The manual outlining of hepatic metastasis in (US) ultrasound acquisitions from patients suffering from pancreatic cancer is common practice. However, such pure manual measurements are often very time consuming, and the results repeatedly…

Computer Vision and Pattern Recognition · Computer Science 2018-03-13 Jan Egger , Xiaojun Chen , Lucas Bettac , Mark Hänle , Tilmann Gräter , Wolfram Zoller , Dieter Schmalstieg , Alexander Hann

Colorectal diseases, including inflammatory conditions and neoplasms, require quick, accurate care to be effectively treated. Traditional diagnostic pipelines require extensive preparation and rely on separate, individual evaluations on…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Krithik Ramesh , Ritvik Koneru

Hepatocellular carcinoma is the most spread primary liver cancer across the world ($\sim$80\% of the liver tumors). The gold standard for HCC diagnosis is liver biopsy. However, in the clinical routine, expert radiologists provide a visual…

Computer Vision and Pattern Recognition · Computer Science 2025-01-15 E. Sarfati , A. Bône , M-M. Rohé , C. Aubé , M. Ronot , P. Gori , I. Bloch

Non-Alcoholic Fatty Liver Disease (NAFLD) is becoming increasingly prevalent in the world population. Without diagnosis at the right time, NAFLD can lead to non-alcoholic steatohepatitis (NASH) and subsequent liver damage. The diagnosis and…

Image and Video Processing · Electrical Eng. & Systems 2020-09-23 Ananya Jana , Hui Qu , Puru Rattan , Carlos D. Minacapelli , Vinod Rustgi , Dimitris Metaxas

Purpose: To present a high-performing, robust, and flexible deep learning pipeline for automatic segmentation of 30 organs-at-risk (OARs) in head and neck (H&N) cancer patients, using MRI, CT, or both. Method: We trained a segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-09-08 Sébastien Quetin , Andrew Heschl , Mauricio Murillo , Rohit Murali , Piotr Pater , George Shenouda , Shirin A. Enger , Farhad Maleki

Deep learning has been shown to be useful to detect breast cancer metastases by analyzing whole slide images of sentinel lymph nodes. However, it requires extensive scanning and analysis of all the lymph nodes slides for each case. Our deep…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Kareem Allam , Xiaohong Iris Wang , Songlin Zhang , Jianmin Ding , Kevin Chiu , Karan Saluja , Amer Wahed , Hongxia Sun , Andy N. D. Nguyen

Background: The aim of this study was to develop and evaluate a deep learning-based automated segmentation method for hepatic anatomy (i.e., parenchyma, tumors, portal vein, hepatic vein and biliary tree) from the hepatobiliary phase of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-21 Karin A. Olthof , Matteo Fusagli , Bianca Güttner , Tiziano Natali , Bram Westerink , Stefanie Speidel , Theo J. M. Ruers , Koert F. D. Kuhlmann , Andrey Zhylka

Objectives- Several ultrasound measures have shown promise for assessment of steatosis compared to traditional B-scan, however clinicians may be required to integrate information across the parameters. Here, we propose an integrated…

Medical Physics · Physics 2024-04-03 Jihye Baek , Ahmed El Kaffas , Aya Kamaya , Kenneth Hoyt , Kevin J. Parker

Stereotactic Body Radiation Therapy (SBRT) can be a precise, minimally invasive treatment method for liver cancer and liver metastases. However, the effectiveness of SBRT relies on the accurate delivery of the dose to the tumor while…

Medical Physics · Physics 2024-11-26 Sugandima Weragoda , Ping Xia , Kevin Stephans , Neil Woody , Michael Martens , Robert Brown , Bingqi Guo
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