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Early detection of lung cancer is critical to improving survival outcomes. We present a deep learning framework for automated lung cancer screening from chest computed tomography (CT) images with integrated explainability. Using the…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Nishan Rai , Sujan Khatri , Devendra Risal

Digital mammography is essential to breast cancer detection, and deep learning offers promising tools for faster and more accurate mammogram analysis. In radiology and other high-stakes environments, uninterpretable ("black box") deep…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Julia Yang , Alina Jade Barnett , Jon Donnelly , Satvik Kishore , Jerry Fang , Fides Regina Schwartz , Chaofan Chen , Joseph Y. Lo , Cynthia Rudin

Cancer treatments require personalized approaches based on a patient's clinical condition, medical history, and evidence-based guidelines. The National Comprehensive Cancer Network (NCCN) provides frequently updated, complex guidelines…

Information Retrieval · Computer Science 2025-02-25 Abdul M. Mohammed , Iqtidar Mansoor , Sarah Blythe , Dennis Trujillo

Interpretable insights from predictive models remain critical in bio-statistics, particularly when assessing causality, where classical statistical and machine learning methods often provide inherent clarity. While Neural Networks (NNs)…

Applications · Statistics 2025-05-02 Jean-Baptiste A. Conan

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

The proliferation of high-dimensional datasets in fields such as genomics, healthcare, and finance has created an urgent need for machine learning models that are both highly accurate and inherently interpretable. While traditional deep…

Machine Learning · Computer Science 2025-10-28 Rekha R Nair , Tina Babu , Alavikunhu Panthakkan , Hussain Al-Ahmad , Balamurugan Balusamy

Prostate cancer, the second most prevalent male malignancy, requires advanced diagnostic tools. We propose an explainable AI system combining BERT (for textual clinical notes) and Random Forest (for numerical lab data) through a novel…

Skin cancer is a serious worldwide health issue, precise and early detection is essential for better patient outcomes and effective treatment. In this research, we use modern deep learning methods and explainable artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Faysal Mahmud , Md. Mahin Mahfiz , Md. Zobayer Ibna Kabir , Yusha Abdullah

There are various algorithms and methodologies used for automated screening of cervical cancer by segmenting and classifying cervical cancer cells into different categories. This study presents a critical review of different research papers…

Machine Learning · Computer Science 2018-11-05 Yasha Singh , Dhruv Srivastava , P. S. Chandranand , Dr. Surinder Singh

Breast cancer is one of the most threatening diseases in women's life; thus, the early and accurate diagnosis plays a key role in reducing the risk of death in a patient's life. Mammography stands as the reference technique for breast…

Machine Learning · Computer Science 2023-05-05 Juan Zuluaga-Gomez

Artificial Intelligence (AI) technology is based on theory and development of computer systems able to perform tasks that normally require human intelligence. In this context, deep learning is a family of computational methods that allow an…

Computers and Society · Computer Science 2019-05-17 Mario Coccia

Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 MingXuan Xiao , Yufeng Li , Xu Yan , Min Gao , Weimin Wang

Computer aided detection and diagnosis systems based on deep learning have shown promising performance in breast cancer detection. However, there are cases where the obtained results lack justification. In this study, our objective is to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Imane Nedjar , Mohammed Brahimi , Said Mahmoudi , Khadidja Abi Ayad , Mohammed Amine Chikh

Prostate cancer is a leading cause of mortality in men, yet interpretation of T2-weighted prostate MRI remains challenging due to subtle and heterogeneous lesions. We developed an interpretable framework for automatic cancer detection using…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Vahid Monfared , Mohammad Hadi Gharib , Ali Sabri , Maryam Shahali , Farid Rashidi , Amit Mehta , Reza Rawassizadeh

Mammography is the most effective and available tool for breast cancer screening. However, the low positive predictive value of breast biopsy resulting from mammogram interpretation leads to approximately 70% unnecessary biopsies with…

Machine Learning · Computer Science 2013-06-04 Sahar A. Mokhtar , Alaa. M. Elsayad

We investigated the data-driven relationship between features in the tumor microenvironment (TME) and the overall and 5-year survival in triple-negative breast cancer (TNBC) and non-TNBC (NTNBC) patients by using Explainable Artificial…

Breast cancer is the most common cancer among women worldwide. Early-stage diagnosis of breast cancer can significantly improve the efficiency of treatment. Computer-aided diagnosis (CAD) systems are widely adopted in this issue due to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Mohammad Reza Abbasniya , Sayed Ali Sheikholeslamzadeh , Hamid Nasiri , Samaneh Emami

Timely brain tumor diagnosis remains challenging in low-resource clinical environments where expert neuroradiology interpretation, high-end MRI hardware, and invasive biopsy procedures may be limited. Although deep learning has achieved…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Areeb Ehsan

The development of AI-based methods to analyze radiology reports could lead to significant advances in medical diagnosis, from improving diagnostic accuracy to enhancing efficiency and reducing workload. However, the lack of…

Computation and Language · Computer Science 2025-08-14 Yuyan Ge , Kwan Ho Ryan Chan , Pablo Messina , René Vidal

An important part of breast cancer staging is the assessment of the sentinel axillary node for early signs of tumor spreading. However, this assessment by pathologists is not always easy and retrospective surveys often requalify the status…

Quantitative Methods · Quantitative Biology 2024-04-30 Eric Bonnet