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We study the network reconstruction problem for an epidemic reaction-diffusion. These models are an extension of deterministic, compartmental models to a graph setting, where the reactions within the nodes are coupled by a diffusion. We…
In the real world, many complex systems interact with other systems. In addition, the intra- or inter-systems for the spread of information about infectious diseases and the transmission of infectious diseases are often not random, but with…
A key problem in modelling the evolution dynamics of infectious diseases is the mathematical representation of the mechanism of transmission of the contagion. Models with a finite number of subpopulations can be described via systems of…
The effect of diffusion rates on the basic reproduction number of a general compartmental reaction-diffusion epidemic model in a heterogeneous environment is considered. It is shown when the diffusion rates tend to zero, the limit of the…
We consider epidemic extinction in finite networks with broad variation in local connectivity. Generalizing the theory of large fluctuations to random networks with a given degree distribution, we are able to predict the most probable, or…
Epidemic spreading often occurs in spatially heterogeneous environments, yet how quenched heterogeneity reshapes its onset and critical dynamics remains poorly understood. The diffusive epidemic process, a minimal reaction-diffusion model…
Real epidemic spreading networks often composed of several kinds of networks interconnected with each other, and the interrelated networks have the different topologies and epidemic dynamics. Moreover, most human diseases are derived from…
We study a simple reaction-diffusion population model [proposed by A. Windus and H. J. Jensen, J. Phys. A: Math. Theor. 40, 2287 (2007)] on scale-free networks. In the case of fully random diffusion, the network topology cannot affect the…
We review and introduce a generalized reaction-diffusion approach to epidemic spreading in a metapopulation modeled as a complex network. The metapopulation consists of susceptible and infected individuals that are grouped in subpopulations…
Resource diffusion is an ubiquitous phenomenon, but how it impacts epidemic spreading has received little study. We propose a model that couples epidemic spreading and resource diffusion in multiplex networks. The spread of disease in a…
Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…
In this paper, we explore the solvability and the optimal control problem for a compartmental model based on reaction-diffusion partial differential equations describing a transmissible disease. The nonlinear model takes into account the…
The basic and effective reproduction numbers are widely used metrics for characterizing the dynamics of infectious disease epidemics. However, the interpretation of these numbers is based on the assumption of homogeneous mixing and may not…
In this paper, we consider an optimal distributed control problem for a reaction-diffusion-based SIR epidemic model with human behavioral effects. We develop a model wherein non-pharmaceutical intervention methods are implemented, but a…
This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…
Reaction-diffusion systems offer a powerful framework for understanding self-organized patterns in biological systems, yet controlling these patterns remains a significant challenge. As a consequence, we present a rigorous framework of…
It is often useful to represent the infectious dynamics of mobile agents by metapopulation models. In such a model, metapopulations form a static network, and individuals migrate from one metapopulation to another. It is known that…
We propose an efficient strategy to suppress epidemic explosion in heterogeneous metapopulation networks, wherein each node represents a subpopulation with any number of individuals and is assigned a curing rate that is proportional to…
We develop a feedback control method for networked epidemic spreading processes. In contrast to most prior works which consider mean field, open-loop control schemes, the present work develops a novel framework for feedback control of…
During the COVID-19 pandemic, different countries, regions, and communities constructed various epidemic models to evaluate spreading behaviors and assist in making mitigation policies. Model uncertainties, introduced by complex…