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Identifying the spatio-temporal network structure of brain activity from multi-neuronal data streams is one of the biggest challenges in neuroscience. Repeating patterns of precisely timed activity across a group of neurons is potentially…

Neurons and Cognition · Quantitative Biology 2009-03-03 Casey Diekman , Kohinoor Dasgupta , Vijay Nair , P. S. Sastry , K. P. Unnikrishnan

Brain decoding involves the determination of a subject's cognitive state or an associated stimulus from functional neuroimaging data measuring brain activity. In this setting the cognitive state is typically characterized by an element of a…

Machine Learning · Statistics 2015-04-14 Nicole Croteau , Farouk S. Nathoo , Jiguo Cao , Ryan Budney

Neural recordings are nonstationary time series, i.e. their properties typically change over time. Identifying specific changes, e.g. those induced by a learning task, can shed light on the underlying neural processes. However, such changes…

Quantitative Methods · Quantitative Biology 2013-01-28 Duncan A. J. Blythe , Frank C. Meinecke , Paul von Buenau , Klaus-Robert Mueller

This paper models the dynamics of a large set of interacting neurons within the framework of statistical field theory. We use a method initially developed in the context of statistical field theory [44] and later adapted to complex systems…

Neurons and Cognition · Quantitative Biology 2022-05-25 Pierre Gosselin , Aïleen Lotz , Marc Wambst

The correlated variability in the responses of a neural population to the repeated presentation of a sensory stimulus is a universally observed phenomenon. Such correlations have been studied in much detail, both with respect to their…

Neurons and Cognition · Quantitative Biology 2018-07-04 Volker Pernice , Rava Azeredo da Silveira

Sensory neurons often have variable responses to repeated presentations of the same stimulus, which can significantly degrade the stimulus information contained in those responses. This information can in principle be preserved if…

Neurons and Cognition · Quantitative Biology 2019-04-24 Matthew R Whiteway , Karolina Socha , Vincent Bonin , Daniel A Butts

One major challenge in neuroscience is the identification of interrelations between signals reflecting neural activity and how information processing occurs in the neural circuits. At the cellular and molecular level, mechanisms of signal…

Applications · Statistics 2019-09-27 Giacomo Aletti , Davide Lonardoni , Giovanni Naldi , Thierry Nieus

For the past few years, we have developed flexible, active, multiplexed recording devices for high resolution recording over large, clinically relevant areas in the brain. While this technology has enabled a much higher-resolution view of…

Neurons and Cognition · Quantitative Biology 2017-06-06 Yilin Song , Jonathan Viventi , Yao Wang

Whether, when, and how causal interactions between neurons can be meaningfully studied from observations of neural activity alone are vital questions in neural data analysis. Here we aim to better outline the concept of functional…

Neurons and Cognition · Quantitative Biology 2023-12-05 Ian H. Stevenson

Brain activity is intrinsically a neural dynamic process constrained by anatomical space. This leads to significant variations in spatial distribution patterns and correlation patterns of neural activity across variable and heterogeneous…

Machine Learning · Computer Science 2026-03-10 Hongjie Jiang , Yifei Tang , Shuqiang Wang

We investigate the stimulus-dependent tuning properties of a noisy ionic conductance model for intrinsic subthreshold oscillations in membrane potential and associated spike generation. On depolarization by an applied current, the model…

Neurons and Cognition · Quantitative Biology 2009-11-11 Martin Tobias Huber And Hans Albert Braun

Much of the information the brain processes and stores is temporal in nature - a spoken word or a handwritten signature, for example, is defined by how it unfolds in time. However, it remains unclear how neural circuits encode complex…

Neurons and Cognition · Quantitative Biology 2017-08-15 Vishwa Goudar , Dean Buonomano

Neuroscientists have enjoyed much success in understanding brain functions by constructing brain connectivity networks using data collected under highly controlled experimental settings. However, these experimental settings bear little…

Machine Learning · Statistics 2019-06-24 Kean Ming Tan , Junwei Lu , Tong Zhang , Han Liu

There has been tremendous interest in designing stimuli (e.g. electrical currents) that produce desired neural responses, e.g., for inducing therapeutic effects for treatments. Traditionally, the design of such stimuli has been…

Applications · Statistics 2023-06-01 Chaitanya Goswami , Pulkit Grover

Neural processes have recently emerged as a class of powerful neural latent variable models that combine the strengths of neural networks and stochastic processes. As they can encode contextual data in the network's function space, they…

Machine Learning · Computer Science 2021-12-03 Jiayi Shen , Xiantong Zhen , Marcel Worring , Ling Shao

A central issue in neural recording is that of distinguishing the activities of many neurons. Here, we develop a framework, based on Fisher information, to quantify how separable a neuron's activity is from the activities of nearby neurons.…

Cortical neurons are subject to sustained and irregular synaptic activity which causes important fluctuations of the membrane potential (Vm). We review here different methods to characterize this activity and its impact on spike generation.…

Neurons and Cognition · Quantitative Biology 2009-04-29 Zuzanna Piwkowska , Martin Pospischil , Romain Brette , Julia Sliwa , Michelle Rudolph-Lilith , Thierry Bal , Alain Destexhe

The growing interest in brain-inspired computational models arises from the remarkable problem-solving efficiency of the human brain. Action recognition, a complex task in computational neuroscience, has received significant attention due…

Neural and Evolutionary Computing · Computer Science 2024-06-18 Alireza Nadafian , Milad Mozafari , Timothée Masquelier , Mohammad Ganjtabesh

Neural networks exhibit a remarkable degree of representational convergence across diverse architectures, training objectives, and even data modalities. This convergence is predictive of alignment with brain representation. A recent…

Neurons and Cognition · Quantitative Biology 2026-04-24 Eghbal A. Hosseini , Brian Cheung , Evelina Fedorenko , Alex H. Williams

The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes. Established approaches rely mostly on deviations of a given network from certain…

Neurons and Cognition · Quantitative Biology 2014-09-19 Marc-Thorsten Huett , Marcus Kaiser , Claus C. Hilgetag