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A major challenge for cancer pathologists is to determine whether a new tumor in a patient with cancer is a metastasis or an independent occurrence of the disease. In recent years numerous studies have evaluated pairs of tumor specimens to…

Applications · Statistics 2015-11-18 Irina Ostrovnaya , Venkatraman E. Seshan , Colin B. Begg

Clustering is a technique for the analysis of datasets obtained by empirical studies in several disciplines with a major application for biomedical research. Essentially, clustering algorithms are executed by machines aiming at finding…

Quantitative Methods · Quantitative Biology 2024-09-30 Diego Ulisse Pizzagalli , Santiago Fernandez Gonzalez , Rolf Krause

Cluster matching by permuting cluster labels is important in many clustering contexts such as cluster validation and cluster ensemble techniques. The classic approach is to minimize the euclidean distance between two cluster solutions which…

Artificial Intelligence · Computer Science 2007-05-31 Jens Oehlschlägel

Clustering is a popular unsupervised learning tool often used to discover groups within a larger population such as customer segments, or patient subtypes. However, despite its use as a tool for subgroup discovery and description - few…

Machine Learning · Computer Science 2021-12-13 Connor Lawless , Jayant Kalagnanam , Lam M. Nguyen , Dzung Phan , Chandra Reddy

Consider a population consisting of clusters of sampling units, evolving temporally, spatially, or according to other dynamics. We wish to monitor the evolution of its means, medians, or other parameters. For administrative convenience and…

Methodology · Statistics 2020-04-30 Jiahua Chen , Yukun Liu , James Zidek

In an age of increasingly large data sets, investigators in many different disciplines have turned to clustering as a tool for data analysis and exploration. Existing clustering methods, however, typically depend on several nontrivial…

Quantitative Methods · Quantitative Biology 2009-11-11 Noam Slonim , Gurinder Singh Atwal , Gasper Tkacik , William Bialek

In this work, the possibility of clustering correlated random variables was examined, both because of their mutual similarity and because of their similarity to the principal components. The k-means algorithm and spectral algorithms were…

Machine Learning · Computer Science 2019-09-10 Zenon Gniazdowski , Dawid Kaliszewski

We introduce a tensor-based clustering method to extract sparse, low-dimensional structure from high-dimensional, multi-indexed datasets. This framework is designed to enable detection of clusters of data in the presence of structural…

Quantitative Methods · Quantitative Biology 2019-02-11 Anna Seigal , Mariano Beguerisse-Díaz , Birgit Schoeberl , Mario Niepel , Heather A. Harrington

In this paper we propose a unified framework to simultaneously discover the number of clusters and group the data points into them using subspace clustering. Real data distributed in a high-dimensional space can be disentangled into a union…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Jie Liang , Jufeng Yang , Ming-Ming Cheng , Paul L. Rosin , Liang Wang

We introduce a new method for performing clustering with the aim of fitting clusters with different scatters and weights. It is designed by allowing to handle a proportion $\alpha$ of contaminating data to guarantee the robustness of the…

Statistics Theory · Mathematics 2008-12-18 Luis A. García-Escudero , Alfonso Gordaliza , Carlos Matrán , Agustin Mayo-Iscar

While clustering is ubiquitously used across science and industry, uncertainty in cluster assignments is rarely quantified with rigorous guarantees. We propose a novel conformal inference framework for clustering that returns confidence…

Methodology · Statistics 2026-04-13 YoonHaeng Hur , Anirban Nath , Genevera Allen

Many real-life data are described by categorical attributes without a pre-classification. A common data mining method used to extract information from this type of data is clustering. This method group together the samples from the data…

Machine Learning · Computer Science 2014-07-30 Fabricio Olivetti de França

To cluster data is to separate samples into distinctive groups that should ideally have some cohesive properties. Today, numerous clustering algorithms exist, and their differences lie essentially in what can be perceived as ``cohesive…

Machine Learning · Statistics 2025-05-08 Louis Ohl , Pierre-Alexandre Mattei , Frédéric Precioso

Cluster analysis methods seek to partition a data set into homogeneous subgroups. It is useful in a wide variety of applications, including document processing and modern genetics. Conventional clustering methods are unsupervised, meaning…

Methodology · Statistics 2014-07-11 Eric Bair

Functional data clustering is to identify heterogeneous morphological patterns in the continuous functions underlying the discrete measurements/observations. Application of functional data clustering has appeared in many publications across…

Methodology · Statistics 2022-10-04 Mimi Zhang , Andrew Parnell

Data analysis plays an indispensable role for value creation in industry. Cluster analysis in this context is able to explore given datasets with little or no prior knowledge and to identify unknown patterns. As (big) data complexity…

Machine Learning · Computer Science 2021-06-25 Marc Wegmann , Domenique Zipperling , Jonas Hillenbrand , Jürgen Fleischer

We investigate task clustering for deep-learning based multi-task and few-shot learning in a many-task setting. We propose a new method to measure task similarities with cross-task transfer performance matrix for the deep learning scenario.…

Machine Learning · Computer Science 2018-05-21 Mo Yu , Xiaoxiao Guo , Jinfeng Yi , Shiyu Chang , Saloni Potdar , Gerald Tesauro , Haoyu Wang , Bowen Zhou

The problem of hierarchical clustering items from pairwise similarities is found across various scientific disciplines, from biology to networking. Often, applications of clustering techniques are limited by the cost of obtaining…

Machine Learning · Statistics 2012-07-20 Brian Eriksson

Clustering is a widely used unsupervised learning method for finding structure in the data. However, the resulting clusters are typically presented without any guarantees on their robustness; slightly changing the used data sample or…

Machine Learning · Statistics 2017-01-02 Andreas Henelius , Kai Puolamäki , Henrik Boström , Panagiotis Papapetrou

Challenges of assessing complexity and clonality in populations of mixed species arise in diverse areas of modern biology, including estimating diversity and clonality in microbiome populations, measuring patterns of T and B cell clonality,…

Methodology · Statistics 2014-08-07 Yi Liu , Andrew Z. Fire , Scott Boyd , Richard A. Olshen