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As sequencing technologies become more affordable and genomic databases expand continuously, the reuse of publicly available sequencing data emerges as a powerful strategy for studying microbial pathogens. Indeed, raw sequencing reads…

Quantitative Methods · Quantitative Biology 2025-05-16 Damien Richard , Nils Poulicard

Networks are important storage data structures now used to store personal information of individuals around the globe. With the advent of personal genome sequencing, networks are going to be used to store personal genomic sequencing of…

Social and Information Networks · Computer Science 2017-08-22 Komal Batool , Muaz A. Niazi

DNA sequencing is becoming increasingly commonplace, both in medical and direct-to-consumer settings. To promote discovery, collected genomic data is often de-identified and shared, either in public repositories, such as OpenSNP, or with…

Machine Learning · Computer Science 2022-12-21 Rajagopal Venkatesaramani , Bradley A. Malin , Yevgeniy Vorobeychik

Genome data are crucial in modern medicine, offering significant potential for diagnosis and treatment. Thanks to technological advancements, many millions of healthy and diseased genomes have already been sequenced; however, obtaining the…

Genomics · Quantitative Biology 2024-06-18 Teddy Lazebnik , Liron Simon-Keren

The re-identification or de-anonymization of users from anonymized data through matching with publicly-available correlated user data has raised privacy concerns, leading to the complementary measure of obfuscation in addition to…

Information Theory · Computer Science 2022-09-16 Serhat Bakirtas , Elza Erkip

A mechanism for releasing information about a statistical database with sensitive data must resolve a trade-off between utility and privacy. Privacy can be rigorously quantified using the framework of {\em differential privacy}, which…

Databases · Computer Science 2009-03-20 Arpita Ghosh , Tim Roughgarden , Mukund Sundararajan

Since the global spread of Covid-19 began to overwhelm the attempts of governments to conduct manual contact-tracing, there has been much interest in using the power of mobile phones to automate the contact-tracing process through the…

Cryptography and Security · Computer Science 2020-11-10 Abbas Hammoud , Yun William Yu

We provide a security analysis for continuous variable quantum key distribution protocols based on the transmission of squeezed vacuum states measured via homodyne detection. We employ a version of the entropic uncertainty relation for…

Many differentially private algorithms for answering database queries involve a step that reconstructs a discrete data distribution from noisy measurements. This provides consistent query answers and reduces error, but often requires space…

Machine Learning · Computer Science 2021-10-27 Ryan McKenna , Siddhant Pradhan , Daniel Sheldon , Gerome Miklau

Probabilistic counters are well-known tools often used for space-efficient set cardinality estimation. In this paper, we investigate probabilistic counters from the perspective of preserving privacy. We use the standard, rigid differential…

Cryptography and Security · Computer Science 2026-03-11 Dominik Bojko , Krzysztof Grining , Marek Klonowski

In medical organizations large amount of personal data are collected and analyzed by the data miner or researcher, for further perusal. However, the data collected may contain sensitive information such as specific disease of a patient and…

Cryptography and Security · Computer Science 2012-03-19 Pawan R Bhaladhare , Devesh Jinwala

Differential Privacy (DP) considers a scenario in which an adversary has almost complete information about the entries of a database. This worst-case assumption is likely to overestimate the privacy threat faced by an individual in…

Cryptography and Security · Computer Science 2026-02-11 Dennis Breutigam , Rüdiger Reischuk

Over-parameterized models have raised concerns about their potential to memorize training data, even when achieving strong generalization. The privacy implications of such memorization are generally unclear, particularly in scenarios where…

Machine Learning · Computer Science 2025-05-27 Daniel Barzilai , Yuval Margalit , Eitan Gronich , Gilad Yehudai , Meirav Galun , Ronen Basri

We consider the problem of computing tight privacy guarantees for the composition of subsampled differentially private mechanisms. Recent algorithms can numerically compute the privacy parameters to arbitrary precision but must be carefully…

Cryptography and Security · Computer Science 2025-04-09 Christian Janos Lebeda , Matthew Regehr , Gautam Kamath , Thomas Steinke

Modern biological science produces vast amounts of genomic sequence data. This is fuelling the need for efficient algorithms for sequence compression and analysis. Data compression and the associated techniques coming from information…

Data Structures and Algorithms · Computer Science 2011-09-05 Heba Afify , Muhammad Islam , Manal Abdel Wahed

Traditional statistical methods for confidentiality protection of statistical databases do not scale well to deal with GWAS (genome-wide association studies) databases especially in terms of guarantees regarding protection from linkage to…

Methodology · Statistics 2012-05-04 Caroline Uhler , Aleksandra B. Slavkovic , Stephen E. Fienberg

The COVID-19 crisis has demonstrated the potential of cutting-edge genomics research. However, privacy of these sensitive pieces of information is an area of significant concern for genomics researchers. The current security models makes it…

Cryptography and Security · Computer Science 2022-04-15 David Reddick , Justin Presley , F. Alex Feltus , Susmit Shannigrahi

In practice, differentially private data releases are designed to support a variety of applications. A data release is fit for use if it meets target accuracy requirements for each application. In this paper, we consider the problem of…

Databases · Computer Science 2021-06-15 Yingtai Xiao , Zeyu Ding , Yuxin Wang , Danfeng Zhang , Daniel Kifer

Differentially private noise mechanisms commonly use symmetric noise distributions. This is attractive both for achieving the differential privacy definition, and for unbiased expectations in the noised answers. However, there are contexts…

Cryptography and Security · Computer Science 2021-10-18 Benjamin M. Case , James Honaker , Mahnush Movahedi

Contact tracing is an effective tool in controlling the spread of infectious diseases such as COVID-19. It involves digital monitoring and recording of physical proximity between people over time with a central and trusted authority, so…

Cryptography and Security · Computer Science 2023-03-13 Craig Gotsman , Kai Hormann
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