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In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

Machine Learning · Computer Science 2016-11-17 Chris Roadknight , Uwe Aickelin , Guoping Qiu , John Scholefield , Lindy Durrant

Multi-instance learning (MIL) is a form of weakly supervised learning where a single class label is assigned to a bag of instances while the instance-level labels are not available. Training classifiers to accurately determine the bag label…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Bin Li , Kevin W. Eliceiri

Patient-level diagnosis of severity in ulcerative colitis (UC) is common in real clinical settings, where the most severe score in a patient is recorded. However, previous UC classification methods (i.e., image-level estimation) mainly…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Kaito Shiku , Kazuya Nishimura , Daiki Suehiro , Kiyohito Tanaka , Ryoma Bise

Early detection of head and neck tumors is crucial for patient survival. Often, diagnoses are made based on endoscopic examination of the larynx followed by biopsy and histological analysis, leading to a high inter-observer variability due…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Marcel Bengs , Stephan Westermann , Nils Gessert , Dennis Eggert , Andreas O. H. Gerstner , Nina A. Mueller , Christian Betz , Wiebke Laffers , Alexander Schlaefer

In the current technological era, the medical profession has emerged as one of the researchers' favorite subject areas, and cancer is one of them. Because there is now no effective treatment for this illness, it is a matter of concern. Only…

Machine Learning · Computer Science 2024-10-23 Praneeth Kumar T , Nidhi Srivastava , Rakshith Mahishi , Chayadevi M L

Multiple Instance Learning (MIL) is a sub-domain of classification problems with positive and negative labels and a "bag" of inputs, where the label is positive if and only if a positive element is contained within the bag, and otherwise is…

Machine Learning · Statistics 2023-10-30 Edward Raff , James Holt

Empirical evaluation of breast tissue biopsies for mitotic nuclei detection is considered an important prognostic biomarker in tumor grading and cancer progression. However, automated mitotic nuclei detection poses several challenges…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Anabia Sohail , Muhammad Ahsan Mukhtar , Asifullah Khan , Muhammad Mohsin Zafar , Aneela Zameer , Saranjam Khan

Early detection of gastric cancer, a leading cause of cancer-related mortality worldwide, remains hampered by the limitations of current diagnostic technologies, leading to high rates of misdiagnosis and missed diagnoses. To address these…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Xian-Xian Liu , Yuanyuan Wei , Mingkun Xu , Yongze Guo , Hongwei Zhang , Huicong Dong , Qun Song , Qi Zhao , Wei Luo , Feng Tien , Juntao Gao , Simon Fong

Aim: Early detection and correct diagnosis of lung cancer are the most important steps in improving patient outcome. This study aims to assess which deep learning models perform best in lung cancer diagnosis. Methods: Non-small cell lung…

Computer Vision and Pattern Recognition · Computer Science 2018-03-16 Zhang Li , Zheyu Hu , Jiaolong Xu , Tao Tan , Hui Chen , Zhi Duan , Ping Liu , Jun Tang , Guoping Cai , Quchang Ouyang , Yuling Tang , Geert Litjens , Qiang Li

Background: Lung cancer ranks as the leading cause of cancer-related mortality worldwide. The complexity of tumor delineation, crucial for radiation therapy, requires expertise often unavailable in resource-limited settings. Artificial…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Yi Luo , Hamed Hooshangnejad , Xue Feng , Gaofeng Huang , Xiaojian Chen , Rui Zhang , Quan Chen , Wil Ngwa , Kai Ding

In the world of medical diagnostics, the adoption of various deep learning techniques is quite common as well as effective, and its statement is equally true when it comes to implementing it into the retina Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2022-03-03 Tasnim Sakib Apon , Mohammad Mahmudul Hasan , Abrar Islam , MD. Golam Rabiul Alam

This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Xirong Li , Yang Zhou , Jie Wang , Hailan Lin , Jianchun Zhao , Dayong Ding , Weihong Yu , Youxin Chen

Multiple instance learning exhibits a powerful approach for whole slide image-based diagnosis in the absence of pixel- or patch-level annotations. In spite of the huge size of hole slide images, the number of individual slides is often…

Breast cancer is one of the most serious types of cancer that can occur in women. The automatic diagnosis of breast cancer by analyzing histological images (HIs) is important for patients and their prognosis. The classification of HIs…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hayder A. Khikani , Naira Elazab , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Diverse applications - particularly in tumour subtyping - have demonstrated the importance of integrative clustering techniques for combining information from multiple data sources. Cluster-Of-Clusters Analysis (COCA) is one such approach…

Machine Learning · Statistics 2020-08-05 Alessandra Cabassi , Paul D. W. Kirk

Multi-Instance Learning (MIL) has shown impressive performance for histopathology whole slide image (WSI) analysis using bags or pseudo-bags. It involves instance sampling, feature representation, and decision-making. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Tingting Zheng , Kui Jiang , Hongxun Yao

Accurate cancer diagnosis remains a critical challenge in digital pathology, largely due to the gigapixel size and complex spatial relationships present in whole slide images. Traditional multiple instance learning (MIL) methods often…

Computer Vision and Pattern Recognition · Computer Science 2024-04-18 Kechun Liu , Wenjun Wu , Joann G. Elmore , Linda G. Shapiro

Clinical diagnostic and treatment decisions rely upon the integration of patient-specific data with clinical reasoning. Cancer presents a unique context that influence treatment decisions, given its diverse forms of disease evolution.…

Image and Video Processing · Electrical Eng. & Systems 2022-12-23 K. Ruwani M. Fernando , Chris P. Tsokos

Accurate identification of breast cancer types plays a critical role in guiding treatment decisions and improving patient outcomes. This paper presents an artificial intelligence enabled tool designed to aid in the identification of breast…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Neil Chaudhary , Zaynah Dhunny

The distinction between malignant and benign tumors is essential to the treatment of cancer. The tissue's elasticity can be used as an indicator for the required tissue characterization. Optical coherence elastography (OCE) probes have been…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Robin Mieling , Johanna Sprenger , Sarah Latus , Lennart Bargsten , Alexander Schlaefer