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In this paper, we present a biologically grounded approach to reservoir computing (RC), in which a network of cultured biological neurons serves as the reservoir substrate. This system, referred to as biological reservoir computing (BRC),…

Neural and Evolutionary Computing · Computer Science 2025-10-08 Ludovico Iannello , Luca Ciampi , Fabrizio Tonelli , Gabriele Lagani , Lucio Maria Calcagnile , Federico Cremisi , Angelo Di Garbo , Giuseppe Amato

In this paper we report a fiber optical sensor system based on surface plasmon resonance (SPR) with real-time response for biochemical interaction analysis. The fiber sensor is constructed from a multi-mode fiber with plastic cladding. To…

Applied Physics · Physics 2019-05-10 Zhixin Tan , Xuejin Li , Yuzhi Chen , Ping Fan

In chemical processing and bioprocessing, conventional online sensors are limited to measure only basic process variables like pressure and temperature, pH, dissolved O and CO$_2$ and viable cell density (VCD). The concentration of other…

Quantitative Methods · Quantitative Biology 2020-05-07 Semion Rozov

Unsupervised estimation of the dimensionality of hyperspectral microspectroscopy datasets containing pure and mixed spectral features, and extraction of their representative endmember spectra, remains a challenge in biochemical data mining.…

Nonlinear optics is essential for many recent photonic technologies. Here, we introduce a novel multi-scale approach to simulate the nonlinear optical response of molecular nanomaterials combining ab initio quantum-chemical and classical…

The characterization of mixtures of non-interacting, spectroscopically similar quantum components has important applications in chemistry, biology, and materials science. We introduce an approach based on quantum tracking control that…

Quantum Physics · Physics 2022-01-26 Alicia B. Magann , Gerard McCaul , Herschel A. Rabitz , Denys I. Bondar

Non-Hermitian systems associated with exceptional points (EPs) are expected to demonstrate a giant response enhancement for various sensors. The widely investigated enhancement mechanism based on diverging from an EP should destroy the EP…

Optics · Physics 2023-07-19 Xuan Mao , Guo-Qing Qin , Hao Zhang , Bo-Yang Wang , Dan Long , Gui-Qin Li , Gui-Lu Long

Reservoir computing (RC) is a state-of-the-art machine learning method that makes use of the power of dynamical systems (the reservoir) for real-time inference. When using biological complex systems as reservoir substrates, it serves as a…

Adaptation and Self-Organizing Systems · Physics 2026-03-03 Mario U. Gaimann , Miriam Klopotek

Living cells communicate information about physiological conditions by producing signaling molecules in a specific timed manner. Different conditions can result in the same total amount of a signaling molecule, differing only in the pattern…

Molecular Networks · Quantitative Biology 2018-10-09 Jackson O'Brien , Arvind Murugan

This article presents a new class of batch-fabricated, low-power and highly sensitive chemiresistive sensors. We first present the design, fabrication and characterization of batch-fabricated sidewall etched vertical nanogap…

Applied Physics · Physics 2020-06-24 Aishwaryadev Banerjee

Characterising optical quantum states is essential for the development of quantum technologies. While traditional approaches to perform full quantum state tomography are often experimentally demanding, neuromorphic architectures may provide…

Developing advanced technologies for sensing and imaging biological samples is crucial for medical applications, making quantum-enhanced methods particularly valuable, as they promise significant benefits over classical techniques. An…

Quantum Physics · Physics 2025-08-21 Cristofero Oglialoro , Enno Giese

Color constancy is a fundamental ability of many biological visual systems and a crucial step in computer imaging systems. Bio-inspired modeling offers a promising way to elucidate the computational principles underlying color constancy and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Kai-Fu Yang , Fu-Ya Luo , Yong-Jie Li

Neuromorphic engineering is a rapidly developing field that aims to take inspiration from the biological organization of neural systems to develop novel technology for computing, sensing, and actuating. The unique properties of such systems…

Systems and Control · Electrical Eng. & Systems 2022-01-26 Luka Ribar , Rodolphe Sepulchre

Physical reservoir computing is a computational framework that implements spatiotemporal information processing directly within physical systems. By exciting nonlinear dynamical systems and creating linear models from their state, we can…

Machine Learning · Computer Science 2025-07-08 Jake Love , Jeroen Mulkers , Robin Msiska , George Bourianoff , Jonathan Leliaert , Karin Everschor-Sitte

By their very nature microscopy images of cells and tissues consist of a limited number of object types or components. In contrast to most natural scenes, the composition is known a priori. Decomposing biological images into semantically…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Avelino Javer , Jens Rittscher

In this article, we report classical sensing with undetected light using octave spanning stimulated four-wave mixing from a plasmonic metasurface. The bidirectional nonlinear scattering due to inherent reflections from such thin nonlinear…

Optical metasurfaces provide novel solutions to label-free biochemical sensing by localizing light resonantly beyond the diffraction limit, thereby selectively enhancing light-matter interactions for improved analytical performance.…

We present a novel multi-modal bio-sensing platform capable of integrating multiple data streams for use in real-time applications. The system is composed of a central compute module and a companion headset. The compute node collects,…

Human-Computer Interaction · Computer Science 2018-02-23 Siddharth , Aashish Patel , Tzyy-Ping Jung , Terrence J. Sejnowski

Artificial Intelligence (AI) drives the creation of future technologies that disrupt the way humans live and work, creating new solutions that change the way we approach tasks and activities, but it requires a lot of data processing, large…

Optics · Physics 2023-06-13 Sendy Phang
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