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In many applications, geodesic hierarchical models are adequate for the study of temporal observations. We employ such a model derived for manifold-valued data to Kendall's shape space. In particular, instead of the Sasaki metric, we adapt…

Methodology · Statistics 2022-03-07 Esfandiar Nava-Yazdani , Hans-Christian Hege , Christoph von Tycowicz

Intrinsic and parametric regression models are of high interest for the statistical analysis of manifold-valued data such as images and shapes. The standard linear ansatz has been generalized to geodesic regression on manifolds making it…

Optimization and Control · Mathematics 2020-10-19 Martin Hanik , Hans-Christian Hege , Anaja Hennemuth , Christoph von Tycowicz

Intensive longitudinal biomarker data are increasingly common in scientific studies that seek temporally granular understanding of the role of behavioral and physiological factors in relation to outcomes of interest. Intensive longitudinal…

Methodology · Statistics 2024-01-17 Mingyan Yu , Zhenke Wu , Margaret Hicken , Michael R. Elliott

Many phenomena are naturally characterized by measuring continuous transformations such as shape changes in medicine or articulated systems in robotics. Modeling the variability in such datasets requires performing statistics on Lie groups,…

Methodology · Statistics 2025-08-19 Johannes Schade , Christoph von Tycowicz , Martin Hanik

When analyzing empirical data, we often find that global linear models overestimate the number of parameters required. In such cases, we may ask whether the data lies on or near a manifold or a set of manifolds (a so-called multi-manifold)…

Machine Learning · Statistics 2018-07-03 F. Patricia Medina , Linda Ness , Melanie Weber , Karamatou Yacoubou Djima

Joint modeling of longitudinal and survival data has become increasingly important in medical research, particularly for understanding disease progression in chronic conditions where both repeated biomarker measurements and time-to-event…

Methodology · Statistics 2025-12-30 Nithisha Suryadevara , Vivek Reddy Srigiri

In a world abundant with diverse data arising from complex acquisition techniques, there is a growing need for new data analysis methods. In this paper we focus on high-dimensional data that are organized into several hierarchical datasets.…

Machine Learning · Computer Science 2021-04-06 Lior Aloni , Omer Bobrowski , Ronen Talmon

The uncertainty of clinical examinations frequently leads to irregular observation intervals in longitudinal imaging data, posing challenges for modeling disease progression.Most existing imaging-based disease prediction models operate in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Xin Hong , Ying Shi , Yinhao Li , Yen-Wei Chen

Joint models for longitudinal and time-to-event data are increasingly used in health research to characterize the association between biomarker trajectories and the risk of clinical events. However, these models usually assume a linear…

Methodology · Statistics 2026-04-21 Denis Rustand , Håvard Rue , Lisa Le Gall , Karen Leffondre

This paper introduces a novel approach to statistics and data analysis, departing from the conventional assumption of data residing in Euclidean space to consider a Riemannian Manifold. The challenge lies in the absence of vector space…

Methodology · Statistics 2024-05-14 Oldemar Rodriguez Rojas

We propose a new method for modelling simple longitudinal data. We aim to do this in a flexible manner (without restrictive assumptions about the shapes of individual trajectories), while exploiting structural similarities between the…

Methodology · Statistics 2024-09-24 Helen Ogden

We introduce a regression model for data on non-linear manifolds. The model describes the relation between a set of manifold valued observations, such as shapes of anatomical objects, and Euclidean explanatory variables. The approach is…

Other Computer Science · Computer Science 2017-03-02 Line Kühnel , Stefan Sommer

The analysis of longitudinal categorical data can be complex and unfeasible due to the number of parameters involved, characterised by overparameterisation leading to model non-convergence, in addition to problems related to sample size and…

We propose a method to learn a distribution of shape trajectories from longitudinal data, i.e. the collection of individual objects repeatedly observed at multiple time-points. The method allows to compute an average spatiotemporal…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Alexandre Bône , Olivier Colliot , Stanley Durrleman

We propose an extrinsic regression framework for modeling data with manifold valued responses and Euclidean predictors. Regression with manifold responses has wide applications in shape analysis, neuroscience, medical imaging and many other…

Statistics Theory · Mathematics 2015-08-11 Lizhen Lin , Brian St. Thomas , Hongtu Zhu , David B. Dunson

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. While there are many advantages to joint modeling, the standard forms suffer from limitations that…

Machine Learning · Statistics 2019-09-09 Bryan Lim , Mihaela van der Schaar

Joint modelling of longitudinal and time-to-event data has received much attention recently. Increasingly, extensions to standard joint modelling approaches are being proposed to handle complex data structures commonly encountered in…

Spatial connectivity is an important consideration when modelling infectious disease data across a geographical region. Connectivity can arise for many reasons, including shared characteristics between regions, and human or vector movement.…

Methodology · Statistics 2022-06-06 Sophie A Lee , Theodoros Economou , Rachel Lowe

Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress…

Machine Learning · Computer Science 2018-03-05 Dev Goyal , Zeeshan Syed , Jenna Wiens

Mixed effect modeling for longitudinal data is challenging when the observed data are random objects, which are complex data taking values in a general metric space without linear structure. In such settings the classical additive error…

Methodology · Statistics 2023-07-13 Satarupa Bhattacharjee , Hans-Georg Müller
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