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Survival analysis is a statistical technique used to estimate the time until an event occurs. Although it is applied across a wide range of fields, adjusting for reporting delays under practical constraints remains a significant challenge…

Machine Learning · Statistics 2025-10-27 Yuta Shikuri , Hironori Fujisawa

Latent Class Models (LCMs) are used to cluster multivariate categorical data (e.g. group participants based on survey responses). Traditional LCMs assume a property called conditional independence. This assumption can be restrictive,…

Machine Learning · Statistics 2024-06-19 Jesse Bowers , Steve Culpepper

In epidemiology, identifying the effect of exposure variables in relation to a time-to-event outcome is a classical research area of practical importance. Incorporating propensity score in the Cox regression model, as a measure to control…

Methodology · Statistics 2019-06-11 Yingrui Yang , Molin Wang

The classical approach to analyze time-to-event data, e.g. in clinical trials, is to fit Kaplan-Meier curves yielding the treatment effect as the hazard ratio between treatment groups. Afterwards commonly a log-rank test is performed in…

Methodology · Statistics 2020-09-16 Kathrin Möllenhoff , Achim Tresch

Structured Latent Attribute Models (SLAMs) are a family of discrete latent variable models widely used in education, psychology, and epidemiology to model multivariate categorical data. A SLAM assumes that multiple discrete latent…

Methodology · Statistics 2021-07-12 Yuqi Gu , Gongjun Xu

We study the multiplicative hazards model with intermittently observed longitudinal covariates and time-varying coefficients. For such models, the existing ad hoc approach, such as the last value carried forward, is biased. We propose a…

Methodology · Statistics 2025-03-13 Zhuowei Sun , Hongyuan Cao

Survival analysis provides a well-established framework for modeling time-to-event data, with hazard and survival functions formally defined as population-level quantities. In applied work, however, these quantities are often interpreted as…

Methodology · Statistics 2026-03-26 Xijia Liu

Usually in Latent Class Analysis (LCA), external predictors are taken to be cluster conditional probability predictors (LC models with covariates), and/or score conditional probability predictors (LC regression models). In such cases, their…

Methodology · Statistics 2018-01-08 Roberto Di Mari , Antonio Punzo , Zsuzsa Bakk

Most prediction models that are used in medical research fail to accurately predict health outcomes due to methodological limitations. Using routinely collected patient data, we explore the use of a Cox proportional hazard (PH) model within…

Methodology · Statistics 2019-07-19 John Mbotwa , Marc de Kamps , Paul D. Baxter , Mark S. Gilthorpe

Temporal Point Processes (TPP) with partial likelihoods involving a latent structure often entail an intractable marginalization, thus making inference hard. We propose a novel approach to Maximum Likelihood Estimation (MLE) involving…

Machine Learning · Computer Science 2019-12-20 Amrith Setlur , Barnabás Póczós

Unlike the commonly used parametric regression models such as mixed models, that can easily violate the required statistical assumptions and result in invalid statistical inference, target maximum likelihood estimation allows more realistic…

Applications · Statistics 2020-06-17 Chi Zhang , Jennifer Ahern , Mark J. van der Laan

A class of estimating functions is introduced for the regression parameter of the Cox proportional hazards model to allow unknown failure statuses on some study subjects. The consistency and asymptotic normality of the resulting estimators…

Statistics Theory · Mathematics 2007-08-22 Irene Gijbels , Danyu Lin , Zhiliang Ying

Estimating causal effects from nonexperimental data is a fundamental problem in many fields of science. A key component of this task is selecting an appropriate set of covariates for confounding adjustment to avoid bias. Most existing…

Machine Learning · Computer Science 2025-10-28 Zheng Li , Xichen Guo , Feng Xie , Yan Zeng , Hao Zhang , Zhi Geng

Latent class growth analysis is a popular approach to identify underlying subpopulations. Several implementations, such as LCGA (Mplus), Proc Traj (SAS) and lcmm (R) are specially designed for this purpose. Motivated by data collection of…

Applications · Statistics 2021-08-17 Jianhui Gao , Aliza Panjwani , Madeline Li , Osvaldo Espin-Garcia

The cumulative incidence is the probability of failure from the cause of interest over a certain time period in the presence of other risks. A semiparametric regression model proposed by Fine and Gray (1999) has become the method of choice…

Methodology · Statistics 2016-03-02 Lu Mao , D. Y. Lin

In a real-life setting, little is known regarding the effectiveness of statins for primary prevention among older adults, and analysis of observational data can add crucial information on the benefits of actual patterns of use. Latent class…

Methodology · Statistics 2023-10-18 Awa Diop , Caroline Sirois , Jason Robert Guertin , Denis Talbot

Hierarchical latent tree analysis (HLTA) is recently proposed as a new method for topic detection. It differs fundamentally from the LDA-based methods in terms of topic definition, topic-document relationship, and learning method. It has…

Machine Learning · Computer Science 2015-08-06 Peixian Chen , Nevin L. Zhang , Leonard K. M. Poon , Zhourong Chen

Most current word prediction systems make use of n-gram language models (LM) to estimate the probability of the following word in a phrase. In the past years there have been many attempts to enrich such language models with further…

Computation and Language · Computer Science 2008-01-31 Tonio Wandmacher , Jean-Yves Antoine

The latent class model is a widely used mixture model for multivariate discrete data. Besides the existence of qualitatively heterogeneous latent classes, real data often exhibit additional quantitative heterogeneity nested within each…

Methodology · Statistics 2025-01-23 Zhongyuan Lyu , Ling Chen , Yuqi Gu

Network meta-analysis (NMA) of rare events has attracted little attention in the literature. Until recently, networks of interventions with rare events were analyzed using the inverse-variance NMA approach. However, when events are rare the…

Methodology · Statistics 2021-09-22 Theodoros Evrenoglou , Ian White , Sivem Afach , Dimitris Mavridis , Anna Chaimani